| Entry |
|
|---|
| Name |
lavandulyl diphosphate synthase;
FDS-5 |
|---|
| Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only
sub-subclass identified to date)
 |
|---|
| Sysname |
dimethylallyl-diphosphate:dimethylallyl-diphosphate
dimethylallyltransferase (lavandulyl-diphosphate-forming) |
|---|
| Reaction(IUBMB) |
2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate
[RN:R08950] |
|---|
| Reaction(KEGG) |
R08950
 |
|---|
| Substrate |
dimethylallyl diphosphate [CPD:C00235] |
|---|
| Product |
diphosphate [CPD:C00013];
lavandulyl diphosphate [CPD:C18052] |
|---|
| Comment |
Lavandulyl diphosphate is a monoterpene with a non-head-to-tail
linkage. It is unlike most monoterpenoids, which are derived from
geranyl diphosphate and have isoprene units that are linked
head-to-tail. When this enzyme is incubated with dimethylallyl
diphosphate and isopentenyl diphosphate, it also forms the regular
monoterpene geranyl diphosphate [2]. The enzyme from Artemisia
tridentata (big sagebrush) forms both lavandulyl diphosphate and
chrysanthemyl diphosphate (see EC 2.5.1.67, chrysanthemyl
diphosphate synthase) when dimethylally diphosphate is the sole
substrate. |
|---|
Reference
Authors
Title
Journal
|
1 [PMID:12783539]
Erickson HK, Poulter CD.
Chrysanthemyl diphosphate synthase. The relationship among chain
elongation, branching, and cyclopropanation reactions in the
isoprenoid biosynthetic pathway.
J. Am. Chem. Soc. 125 (2003) 6886-8. |
|---|
Reference
Authors
Title
Journal
Organism
Sequence
|
2 [PMID:12782626]
Hemmerlin A, Rivera SB, Erickson HK, Poulter CD.
Enzymes encoded by the farnesyl diphosphate synthase gene family in
the Big Sagebrush Artemisia tridentata ssp. spiciformis.
J. Biol. Chem. 278 (2003) 32132-40.
Artemisia tridentata ssp. spiciformis
NCBI-GI: 32329200 |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.5.1.69
IUBMB Enzyme Nomenclature: 2.5.1.69
ExPASy - ENZYME nomenclature database: 2.5.1.69
BRENDA, the Enzyme Database: 2.5.1.69 |
|---|
