| Entry |
|
|---|
| Name |
leachianone-G 2''-dimethylallyltransferase;
LG 2''-dimethylallyltransferase;
leachianone G 2''-dimethylallyltransferase;
LGDT |
|---|
| Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only
sub-subclass identified to date)
 |
|---|
| Sysname |
dimethylallyl-diphosphate:leachianone-G 2''-dimethylallyltransferase |
|---|
| Reaction(IUBMB) |
dimethylallyl diphosphate + leachianone G = diphosphate +
sophoraflavanone G [RN:R08952] |
|---|
| Reaction(KEGG) |
R08952
 |
|---|
| Substrate |
dimethylallyl diphosphate [CPD:C00235];
leachianone G [CPD:C18024] |
|---|
| Product |
diphosphate [CPD:C00013];
sophoraflavanone G [CPD:C18053] |
|---|
| Comment |
This membrane-bound enzyme is located in the plastids and requires
Mg2+ for activity. The reaction forms the lavandulyl sidechain of
sophoraflavanone G by transferring a dimethylallyl group to the 2''
position of another dimethylallyl group attached at postiion 8 of
leachianone G. The enzyme is specific for dimethylallyl diphosphate
as the prenyl donor, as it cannot be replaced by isopentenyl
diphosphate or geranyl diphosphate. Euchrenone a7 (a 5-deoxy
derivative of leachianone G) and kenusanone I (a 7-methoxy
derivative of leachianone G) can also act as substrates, but more
slowly. Along with EC 1.14.13.103 (8-dimethylallylnaringenin
2'-hydroxylase) and EC 2.5.1.70 (naringenin
8-dimethylallyltransferase), this enzyme forms part of the
sophoraflavanone-G-biosynthesis pathway. |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:14551337]
Zhao P, Inoue K, Kouno I, Yamamoto H.
Characterization of leachianone G 2"-dimethylallyltransferase, a
novel prenyl side-chain elongation enzyme for the formation of the
lavandulyl group of sophoraflavanone G in Sophora flavescens Ait.
cell suspension cultures.
Plant. Physiol. 133 (2003) 1306-13.
Sophora flavescens Ait. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.5.1.71
IUBMB Enzyme Nomenclature: 2.5.1.71
ExPASy - ENZYME nomenclature database: 2.5.1.71
BRENDA, the Enzyme Database: 2.5.1.71 |
|---|
