KEGG   ENZYME: 2.6.1.12Help
Entry
EC 2.6.1.12                 Enzyme                                 

Name
alanine---oxo-acid transaminase;
L-alanine-alpha-keto acid aminotransferase;
leucine-alanine transaminase;
alanine-keto acid aminotransferase;
alanine-oxo acid aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
L-alanine:2-oxo-acid aminotransferase
Reaction(IUBMB)
L-alanine + a 2-oxo carboxylate = pyruvate + an L-amino acid [RN:R01261]
Reaction(KEGG)
Substrate
L-alanine [CPD:C00041];
2-oxo carboxylate [CPD:C00161]
Product
pyruvate [CPD:C00022];
L-amino acid [CPD:C00151]
Comment
A pyridoxal-phosphate protein.
History
EC 2.6.1.12 created 1961
Pathway
Alanine, aspartate and glutamate metabolism
Metabolic pathways
Reference
1  [PMID:13084587]
  Authors
ALTENBERN RA, HOUSEWRIGHT RD.
  Title
Transaminases in smooth Brucella abortus, strain 19.
  Journal
J. Biol. Chem. 204 (1953) 159-67.
Reference
2  [PMID:13363834]
  Authors
ROWSELL EV.
  Title
Transaminations with pyruvate and other alpha-keto acids.
  Journal
Biochem. J. 64 (1956) 246-52.
Reference
3  [PMID:13385257]
  Authors
SALLACH HJ.
  Title
Formation of serine hydroxypryuvate and L-alanine.
  Journal
J. Biol. Chem. 223 (1956) 1101-8.
Reference
4  [PMID:13174595]
  Authors
WILSON DG, KING KW, BURRIS RH.
  Title
Transamination reactions in plants.
  Journal
J. Biol. Chem. 208 (1954) 863-74.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9030-41-5
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