Escherichia coli clone D i14: i14_2279
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Entry
i14_2279 CDS
T02003
Name
(GenBank) putative peptide/polyketide synthase
KO
K26573
colibactin biosynthesis hybrid nonribosomal peptide/polyketide synthase
Organism
elc
Escherichia coli clone D i14
Pathway
elc01054
Nonribosomal peptide structures
Brite
KEGG Orthology (KO) [BR:
elc00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01054 Nonribosomal peptide structures
i14_2279
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
elc01008
]
i14_2279
Polyketide biosynthesis proteins [BR:
elc01008
]
Polyketide synthase (PKS)
PKS-NRPS hybrid
Bacterial type (modular)
Colibactin synthetase
i14_2279
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AMP-binding
Condensation
ketoacyl-synt
Acyl_transf_1
Ketoacyl-synt_C
PP-binding
KR
ADH_zinc_N_2
ADH_zinc_N
PKS_DH_N
adh_short
adh_short_C2
KAsynt_C_assoc
PS-DH
AMP-binding_C
ADH_N
NAD_binding_10
Epimerase
Thiolase_N
Motif
Other DBs
NCBI-ProteinID:
AER89761
LinkDB
All DBs
Position
complement(2245319..2254948)
Genome browser
AA seq
3209 aa
AA seq
DB search
MMVMDNTSGDFPCNKMDTRKQLPLTPSQQGFLFHSLKDKKRSNYHEHFTCIFSQHVDSAH
FKWALETLFRKHECFRTDYNWEIDERPCQVVKTDVLPDIYVLDCEQEEIRFLLANDDIII
PVPQDDGIDAIIPQLLQADLKYPFSLKTIPVRAYLIQSTKESAFILSYHHIVMDGWSLSL
FIKQLLQLYGAAVVSGVRDDSAIIPSSLKPLVDTLSARRHTFQHDYWAAYLREGTPTCIV
PLSQYHTDTEAENNSYVNQTNHVEINLSPDVCQKIQTLCSDYRITPAVIFYVAWGILLQR
WCYADDVLFGATISGRNIPIDGIEETLGLFINTLPLRLRDDGATLLQHLQRMHQTLIAHY
SNEHDALASIQRLVHKEGHAGDLFNTLVVLENYPVDMTLLSCASPVAIRHLSVHEQTHYP
LTLTITQQKGFRFSIAYALNYLTNNMAQALLMHLSYLLEQLVDNPQRPIAALVNLSPCQQ
AQVLQPYLERMACRDWDSQSNVIEQFHQVAATSPAQVAVVDELCALTYSELAAQAEQLAA
YLVQQGVMVGDTVGIISERRVNTVVAIIAIMLIGAAYVPISPDYPVGRMQEIIDDSGLAL
LLVHGKPLDALNVAQSDLCAFPVAPSVVFPVITPDSRAYVIYSSGSTGKPKGIAVAHRGL
LRLIQGDSPLKVESGETTLLTCPFEFDVSVFEMWSTLLNHGKLVLLSKQALLDINHIRRT
IADEQVARAWFTSSLFNSYVAEGADFFGMLQHITVGGEAVSAWHVNDVMQKYPHLVVTNG
YGPTENTIFTTAYRFNGLQPARVPIGYAVPGTSLYITDLHGHLLPIGATGELVAGGVGVA
IGYQNNPALSATVFVPDPFIPGGMMYKTGDYARLLDDGCVDCFGRKDGQIKINGQRIETG
EIEQRLLECSGIIEAVVVPYRVRETLHIAAVVCVNDSYDEVEVRGQLADRLPPFAIPESL
VVVTEIAKSHSGKADLAQLRYLLPATQCNAVSTTISEVHSDMEHALHAIWQRVLDRQDID
SNASFFALGGTSLDTIRVKGDIKRQLGLEIDITDLFKYPTLTALAHFLDTAVSPEDAIPT
RAVVYSDMPVAIVGMAGRFPGAANIAALWTLVVGGESGLTLFSDEELRAHGVTPDTLKQA
NYIKTKGIVDDHEWFDADFFGYTPNEAECMDPQIRLLHQCCWQTLEHAGCDPATFTGAIG
IYAGLLTSPHWLNAVMQDTTDSTALYKASILNIHSVTALIAHALNLTGPAVTLDTACSTS
AVAIHQACIALRNRDCDAALAGGVSIEMPAYRGYEYHEGMINARDGVCRPFDSQASGTVT
GDGLGMLLLKRLDDALADRDCIYGVIKGSAVNNDGNNKIGYTAPSVIGQSTVIRTSLRRA
GFDSDSIGLVEAHGTGTVLGDPIELRALNEVFGPTPVPFCVVSALKSNIGHLNSAAGVAG
VIKTTLALHHQVLPPTAHFRQLNPAIDLSRSALYVNQQVQPWPSTRPRRALVSSFGIGGT
NASIALEAHQHEDDPSATGVRDSYLLLFSAKTPAALELRVASTLEYVKHGVGVRLPDVAY
TLQTGRTAFDHRRAYLVSRGSKIDLSCATILQAEIFNGQRTTAEICFMFPGQGSQYHGMA
SALYAHQPMFRQHMDRCFAAFQRYSTVDLKALLFDDEDTRDIDQTQFTQPALFCVEYSLA
RTLIDLGITPDSMIGHSLGEYVAACIAGVFTLEDALHVIEARGRLMQSMRPGSMMAVYLS
REQLTPWLAAERGIELAANNSAHFCVVAGEQAAISRLSTRLVEGGIQHRRLKTSHAFHSA
MMTPMLHDFAQLLGQIPMHAPHKRFISNVSGTWITEEQATSPDYWVQQVRNAVLFSEGAA
QLLVQPTLFIECGPGNTLSTFIQGHNQYSDQPTLLTLRKANAAIDDEHMLHRTLAALWVR
GENIDWRRFNQTALGKHIPLPDYPFEQTYYYRYGAALSGYRQYPNPLRRPQDEWLQRVLW
RMHDTSLREAFYAPGELIIIISADGDKLQQTLMSSGVDSITMPLPISSEDDVWDNDRILT
HFHDICALLAHKTYRQLHCLYAPGAEAGSSLTQSLSGLYRVARWCMHSTTPLASLTVLTH
GAFRVQEEDNPEPTLAALSGAVNVFAQELHPTEVRLIDIDAQSSDENLNLLTQRLAPKQE
TVMALRQGMLYLRRFIPTRLLAHLPPQTGCIPGNVLWIIGGEKGIGRMIGEALAQREGVR
VVLSSRTGYHHEAVQQDALDVIHCDVTQAEAVRACLATLLERYGRLDGVIFAADATTTLT
LHQLSESALRDTLTVKERGTANVLHALAQRNLLDERLLLLFCNSLAAVNAEIGQTGYATA
SAYLDALAQQLRTRYKVNALSIGLDALREQGMLLDAINGSEYDVLRGLRPLMTGTLLQAY
KQQGADTSYYARLSPESDWLLDEHRISGIATLPGTGYLALAYEALRHYFVQDQICIDELV
FLAPLTVMDNCSVDVFVDISPNGQGVSVEVKSMTERFSGTLTTHARGRATRLMVDDNVVC
DLTGLMREMHTITPPTKELSSTHFHYGPRWHSVQQLYGNTAQTQVFATLALPTVAANDTI
ALHPALLDIASSVVEQLPGFHTDSVPFLYQDLRLYRPLPNTLHVALTVNRHDEEGDSYAF
TLYDMAGEMVARCAAMVKRKVQLHIQDVDDDTRLRVPSADNYQLRLAAEGEGAGKLALCP
TPRLALGDSQVEIEVLATGLNFKDVLFTTGLLRQQPGEAPLQLGLECAGRITRVGKNVTE
FAPGEDVMAVLNGGFVQYARVESDCVVRKPAHCRIEQAAALPIAYLTAYYALVVRANLQP
GERVLIHSAAGGVGLAALHIAKRCGAQIFATAGSEQKRDYLLSLGVHAVADSHDEQFAAT
LLTASDGQGMDVILNSLTGRLLDASLALLAPLGRFLELGSKDIVEDKALPMRFFAQGGTF
IPINFHAAHGAFSRYLQQIVAWIDDNTLPLLPCKSVPLPEVARAFATLTTPQHIGKVVVT
HRTAAGMDRLNAMIAERRLGGYALSMSNAEVMRQLWPILNTRSPWAQLLLSPRAIDRLAR
GNRVDRGVPSAANDTITQQTVKKRPRPEIGVPYSPATREVERVLCQILEEYLGLDRVGID
DNYAELGATSLDMVQLSGQMARHYPQVSVVSLYNHATVRQLATFCQPPEGESNAPSPQPA
VQTNTRANQIAKRALQIAKNTARSHTSLH
NT seq
9630 nt
NT seq
+upstream
nt +downstream
nt
gtgatggttatggataatacctctggagattttccatgtaataagatggacacgcgtaag
cagttaccgctaacaccaagtcaacaggggtttttattccattccttaaaggataagaaa
aggagtaactaccatgagcattttacatgcattttttctcagcatgtagatagcgcccac
ttcaagtgggcgctggaaacgttatttcgaaagcatgagtgttttcgcactgattataac
tgggagattgatgagcgcccttgtcaggtggtgaagaccgatgtgttgccggatatatat
gtgttagactgtgagcaagaggaaatacgttttctactagctaatgatgacattatcatt
cctgtcccgcaggatgacggtattgatgctataattcctcaactgctacaggctgattta
aaatacccattttccttgaaaacgatcccagtccgggcctaccttattcagtcaacgaaa
gaaagtgcttttatactatcataccatcatattgtgatggatggctggagcttatccctt
ttcattaaacagttgctccaactctatggagcggctgtggtcagtggtgtgagggatgat
agcgccattatcccctcatctctgaaaccccttgtagacacactgtcggcccgacgtcac
acctttcagcacgactattgggctgcatatcttcgggagggaacaccaacttgtatcgtg
ccgctgtcacaatatcacacagatactgaagccgagaacaattcttacgttaatcaaaca
aatcatgtggagatcaatttgtctccggatgtgtgtcagaaaatacagacgctatgcagc
gattatcgtatcacccccgcagtaatcttctatgtggcctggggcatcctgctacaacgt
tggtgctatgctgacgatgtgttattcggcgcgacaatatcagggcgaaatataccaatt
gatggtatagaagaaacactagggctatttattaacacgttgccgctgcgtctgcgtgat
gatggggcgacactgttgcaacacttacaacgtatgcaccaaacactaatagctcactac
agcaatgaacatgatgccttagccagcatacaacggttggtacataaagaaggtcatgct
ggggatctttttaataccttagtggtgttggagaattatcccgttgatatgacattattg
tcatgcgcgtcgcccgtggcaattcgccatctcagtgtacatgaacaaacgcactatccg
ctgaccttgaccatcactcaacagaagggattccgtttcagtattgcatatgcccttaac
tacctgaccaacaacatggcgcaagcgttgctgatgcacctgagttatctgcttgaacaa
ctggtggacaatccgcagcgccccattgctgcgttggtaaacttgtccccatgccagcag
gcgcaggtacttcaaccctatctggaacgcatggcatgccgggattgggatagtcaatcc
aacgtcatcgaacaatttcatcaagttgctgcgacttcgccagcacaggtcgcagtggtt
gatgaattgtgcgcgttgacctattcggagttggcagcacaagctgagcagctcgcggct
tatttggtacagcagggtgttatggttggcgatactgtaggcataattagcgaacgccgg
gtaaacaccgtggttgccatcatcgccatcatgttgatcggggctgcttatgtgcccatc
agccccgactacccagtgggtaggatgcaggaaattattgatgacagcggcttggcgctg
ttgctggtacatggcaaaccgctagatgcattaaacgttgcgcagagtgacctctgtgca
tttcccgtcgcgccctcggtggtatttccggttatcacaccagattctcgcgcttatgtg
atttattcatcggggtcgacgggtaagccaaaaggtatcgcggtggcgcaccgcggttta
ttgcgcctgatacaaggcgacagcccgctgaaggtggagagcggtgagacaacgctgctg
acctgcccatttgagtttgatgtttcggtgtttgagatgtggtctaccttgctcaaccac
ggcaaactagtattactcagcaaacaggcattacttgatatcaatcacattcgccgcacg
atcgctgatgaacaggtggcgcgcgcctggtttacctcatccttgtttaactcctatgtg
gcagaaggtgccgatttcttcggtatgttacaacacattacggtgggcggcgaagcagta
tctgcgtggcatgtcaacgacgtgatgcaaaaatacccgcatctggtggtgacaaacggt
tatgggccgacggaaaacactatttttaccaccgcatatcgtttcaacgggttgcaaccc
gcccgagtcccgataggatacgcggtaccgggcacctcgctctacattaccgatctccat
gggcatttgttgcctatcggtgccaccggtgaactagtggcgggtggagtgggggtcgcc
atcggctatcagaacaacccggcgctaagtgcgacggtttttgtccctgatccttttatt
cccggcggtatgatgtacaaaactggcgattatgcccggttgctggatgatggctgtgtt
gactgttttgggcgtaaagacggtcaaattaagatcaatggacaacgaattgaaaccgga
gagatcgagcagcgcctgctggagtgctccggcattatcgaggcggtagtggttccttac
cgcgtacgtgaaacgctgcatattgcggcagtggtctgcgtcaatgatagctatgatgag
gtggaagttcgagggcaattggctgacagattgccgccattcgctattccggaatccttg
gtggtggtgacggagattgcaaaaagccatagtggcaaggccgacttggcgcagttgcgg
tatctcctgcccgcaactcagtgcaacgccgtgtccaccacgatatcagaggtgcatagt
gacatggaacatgcgctgcatgctatctggcaacgcgtacttgatagacaagacattgat
agcaatgcctcctttttcgccctcggtggcacctcattggataccatcagggttaaaggg
gatattaagcggcaacttggcttggagattgatattaccgatctctttaagtacccaacg
ctcacggcgttagcacattttctcgatactgccgtatcgccggaggatgcaattccaacg
cgtgctgttgtctacagcgacatgccggtggcgattgtcggtatggcgggacgtttcccc
ggtgcggcgaatattgcagcgttgtggacgctggttgtaggaggggaatcgggattaaca
ctgttcagtgatgaagagttgcgcgcgcatggtgtgacacctgacacgcttaaacaagcg
aattatataaaaaccaaagggattgttgatgatcacgaatggtttgatgcggatttcttt
ggttatactcccaacgaggcggaatgtatggatccgcaaattcgcttattgcatcagtgc
tgctggcaaactctggaacacgctgggtgcgatcctgccacctttactggtgcgattggc
atttatgccggactgctgacatccccccactggcttaatgcggtaatgcaagacactacc
gactctaccgccctgtacaaggccagtatcctgaatatccattccgtcacagcattgatt
gcccatgcgcttaacctcaccggccctgccgtgacgcttgacaccgcctgctccacttcg
gcagtggctatccaccaggcctgcatcgcactacgtaaccgggattgcgatgcggcattg
gcgggcggcgtttctatcgagatgcctgcgtaccggggctatgaatatcatgaaggcatg
atcaatgcgcgagatggtgtctgtcgtcctttcgatagccaagcctctggcacagtcacc
ggtgatggcttaggaatgctgctgctaaaacgtctggacgacgcgctggcggatcgggac
tgcatctatggtgtgatcaaaggttcggcggtcaataatgatggcaataacaaaatcggc
tataccgcgccgagtgtgatcgggcaatcaacggtaatccgcaccagtttgcgccgtgcc
ggttttgatagcgacagtatcggattggtggaagcgcacggcaccggtacggtgctgggt
gatcctattgagttacgtgcgcttaatgaggtgtttggcccaacacctgttccgttttgt
gtggtttcagcgctgaaaagtaatattggccacctcaactccgctgcgggagtggcgggc
gtcatcaaaacaacgctcgccctgcatcatcaagtgttgccaccaacagcgcactttcgc
caactcaatcctgctatagatctatcgcgttctgcattgtacgttaaccagcaagtccaa
ccgtggccgtcgacgcgtcctcgtcgtgcactggtgagctccttcggcatcggcggcacc
aatgccagcatcgcactagaagcacatcaacatgaggacgacccttcagcgacgggggta
cgcgacagctatctgttgttgttctccgctaaaacacccgctgcgttagagttgcgcgtg
gcctccacactggaatatgtcaagcatggagtaggggtgcgcctgccggatgtggcttat
acattgcaaactggacgcacagcctttgaccatcggcgggcttatttggtgagtcgtggg
tcgaaaatcgatctctcctgtgccacgatattgcaagcggaaatcttcaatggtcagcgc
acgacagcggagatctgcttcatgtttcctggtcaaggtagccaatatcacggcatggcc
agcgcgctctatgctcatcaacccatgtttcgccagcacatggatcgctgctttgctgca
ttccaacgctattcgacggtcgatctcaaggcgttgttgtttgacgatgaggatacgcgg
gatattgatcaaacgcagttcacacaaccggcgttgttctgtgtcgaatacagcctagcg
cgcaccttgattgatctggggattacgccggacagtatgatcgggcacagtctgggcgag
tatgttgcggcctgtattgctggcgtatttactcttgaggatgcgctgcacgtcattgag
gcgcgcggacgtttgatgcagtccatgcgtcccggtagcatgatggcggtctaccttagt
cgcgaacagttgaccccatggctagctgcagaacggggtattgaactggcagctaataat
agcgcgcatttttgcgtagtcgcgggcgagcaggcggccatttcccgtttgagcacacgc
ttagtcgagggcgggatacagcacaggcgcctgaaaacctctcacgcattccactcggcc
atgatgacgccgatgctgcacgattttgcacagttgctggggcaaatcccgatgcacgcg
ccgcacaagcgctttatatctaatgtaagcggtacatggattactgaggagcaagctacc
tcgccggattactgggtgcagcaagtgcgcaacgcggtgctgtttagcgaaggtgcggcg
caactgttggtacaacccacgctgtttatcgaatgtgggccgggtaatacgctctctacc
tttattcaaggacataaccaatacagcgatcagccgaccctgttgacgctacgcaaagcc
aacgcggcgatcgatgatgagcacatgttgcatcgtacgctggcggcgctgtgggtcagg
ggggagaatattgattggagacgctttaaccagacggcactcggcaagcacattccattg
ccggattaccccttcgaacagacttattactatcgctatggtgctgcactttccggttat
cgccagtatccaaatcctctgcgccgtccgcaagatgagtggctccagcgtgtgctgtgg
cggatgcacgacacatccttgcgggaggcgttctatgcgccgggcgaattgatcatcatt
attagtgctgacggcgacaagttacagcagacgctgatgagtagtggtgtcgacagcatc
acaatgccgctgccgatatcgtcagaggacgacgtgtgggataatgaccgtattctgacg
catttccacgacatctgcgcacttttagcacacaaaacctaccgacagttacattgcttg
tatgctcccggtgcggaggcaggatcatcgttgacacagtcgctctcgggactttatcgt
gttgctcgctggtgtatgcacagcaccacgccgctggcgtccttaacagtattgacccat
ggtgcgtttcgcgtacaggaagaggataatcccgaaccgacgctggcagcgttgtcgggc
gcagtaaacgtgtttgcccaagagctgcacccgaccgaagtacgattgatcgatatcgat
gcgcagagcagtgatgagaatctgaacttgctaacccagcgtctggccccgaaacaagaa
acggtaatggcgctcaggcaggggatgctttacctgcgacgctttatcccgacacggctg
ttggcgcacttaccccctcaaacagggtgtataccgggcaacgtactgtggattatcggc
ggtgaaaaggggattggccgcatgatcggcgaagcgcttgctcagcgtgagggagtccgt
gtggtactgagcagccgcacaggttatcaccatgaagcggtgcagcaggacgcattagac
gttatccactgcgacgtgacgcaggcggaggcggttagagcttgtctggcaactctgctc
gaacgctatggacggttggatggcgtgatttttgctgccgacgctaccaccacattgaca
ctgcatcaattgagcgaatctgcgctacgcgacacgctaacggtgaaagaacggggtact
gctaatgtgctgcatgcgttagcgcaacggaatctgctggatgagcgtctgctactgctg
ttctgtaactcgttggctgccgtgaatgcggagatcggccagacaggctatgctaccgcc
agcgcctatttggatgcactggcacagcaactgcgtacccgctacaaggtgaatgcgctc
agtatcgggttggatgcattgcgtgagcagggcatgttgttggatgctataaacggcagt
gaatacgatgtcttgcgtggactgcgcccattgatgacgggaacgttgctacaggcttat
aaacaacaaggggctgacaccagctactacgcgcgattatcccccgagtccgattggctg
ctggatgagcaccggatatccggtatcgccacgctgccgggaaccggctatctggcgctg
gcgtatgaagctctgcgccattactttgtgcaagaccaaatctgcattgatgaattggtc
tttttggcaccgttgactgtgatggacaactgcagtgttgacgtttttgttgacatttca
cctaacgggcaaggagttagtgtcgaggtgaaatcaatgacggagcgctttagtggcacg
ttaacaacccatgccagaggcagggcgacgcgtctgatggtagacgataatgttgtgtgc
gatctcacggggctgatgcgcgagatgcacactatcactcctccaacaaaggaattatcg
agcacgcacttccactatgggccgcgctggcacagcgtacaacaactgtatggcaatacc
gcccagactcaggttttcgcaacgctggccctgcccaccgttgccgctaatgatacgatc
gcactgcaccctgcgctgttggacatcgccagcagtgttgtcgaacaactgcctggtttt
catactgattcggtacctttcctttatcaggatttacgcctgtaccgcccgttgccgaac
accttacatgtggcgctgactgtcaatcggcacgatgaggagggtgacagctacgctttc
acgctctacgacatggcaggcgagatggttgcccgctgtgcggcaatggtgaagcgcaag
gtacagctccacatacaagatgtcgatgacgacacgcgactgcgcgtgcccagtgccgat
aactaccaactgcggctggccgctgagggggagggggcaggaaagctagcgttgtgccct
acgccgcgcttagcgctgggggattcacaagtagagattgaggtactggccaccggactg
aactttaaggatgtgctgttcaccacgggattgctccggcagcagccgggtgaggctccg
ctgcaattgggactggagtgcgccggacgcattactcgcgtgggtaaaaatgtcactgaa
tttgccccgggagaggatgttatggcggtgctaaacggtggttttgtccagtacgcacgg
gtagaaagcgattgcgtagtgagaaaaccagcccattgtcgcatcgaacaggcggctgcg
ctgcctatcgcatacctcaccgcctattacgcactggtggtgcgcgctaatttgcaaccc
ggagaacgagtattgatccacagtgcggcggggggcgttggcttggctgcgctacatatt
gccaaacgctgcggagcacagattttcgccacagcaggtagcgagcagaaacgcgattac
ttgctttcgctaggcgtacatgccgtagctgattcacacgacgaacagttcgctgccact
ctgctgaccgcatcggacggacaggggatggatgtgatccttaactccctcacaggccgt
ctgcttgacgctagcctcgcgctgctggcaccgctgggccgttttcttgagctgggcagc
aaggacattgtggaagacaaagcgctaccgatgcgtttcttcgcccaaggcggcaccttt
attccgattaattttcacgcggcgcatggtgcgtttagtcgctacctgcaacagattgtc
gcttggatagatgataacacgctaccgctccttccatgcaaatccgtaccattgcccgag
gttgcacgcgccttcgccaccctgaccacgccgcagcatattggcaaggtggtggtaacg
catcgcactgcggcaggcatggaccggctgaacgccatgatagcagaaaggcgcctcggc
ggctatgcgctcagcatgagcaatgccgaggtgatgcgccaattgtggccgatactgaac
actcgcagtccgtgggcgcaactgctgctctcacctcgggcgatcgatagattagcgcgg
ggcaaccgggtggatcgcggtgtaccgtctgccgctaacgatacgattactcagcagaca
gtgaaaaagcggccccgtccggaaattggcgtgccttacagccccgcgacacgtgaagtg
gaacgcgtgctctgccaaatcctggaagagtatctgggtctggatagagtaggcattgac
gacaactatgccgaattaggggcaacctcactcgatatggtgcaactgagtgggcaaatg
gcgcgtcactatccgcaagtgagcgtggtgtcgctgtacaaccacgccaccgtgcgccag
ctggcgacgttttgccagcccccggagggcgagtcaaatgcgccatcaccacagcctgca
gtacagacgaatacgcgcgcgaatcagatagcaaaacgtgctttgcaaattgcgaaaaat
actgcgcgcagtcacacgtctttgcattaa
DBGET
integrated database retrieval system
