KEGG   Escherichia coli O83 H1 NRG 857C (AIEC): NRG857_02510
Entry
NRG857_02510      CDS       T02068                                 
Name
(GenBank) bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase
  KO
K01491  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
Organism
eln  Escherichia coli O83:H1 NRG 857C (AIEC)
Pathway
eln00670  One carbon pool by folate
eln01100  Metabolic pathways
eln01120  Microbial metabolism in diverse environments
eln01200  Carbon metabolism
eln01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:eln00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    NRG857_02510
Enzymes [BR:eln01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     NRG857_02510
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     NRG857_02510
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-ProteinID: ADR25932
UniProt: A0A0H3EFZ1
LinkDB
Position
complement(551821..552687)
AA seq 288 aa
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEE
VGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDV
DGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELL
LAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKV
VGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQGE
NT seq 867 nt   +upstreamnt  +downstreamnt
atggcagcaaagattattgacggtaaaacgattgcgcagcaggtgcgctctgaagttgct
caaaaagttcaggcgcgtattgcagccggactgcgggcgccaggactggccgttgtgctg
gtgggtagcaaccctgcatcgcaaatttatgtcgcaagcaaacgcaaggcttgtgaagaa
gtcgggttcgtctcccgctcttatgacctcccggaaaccaccagcgaagcggagctgctg
gaacttatcgatgcgctgaatgccgacaacaccattgatggcattctggttcaactgccg
ttaccggcgggtattgataacgtcaaagtgctggaacgtattcatccggacaaagacgtg
gacggtttccatccttacaacgtcggtcgtctgtgccagcgcgcgccacgtctgcgtccc
tgtaccccgcgcggtatcgtcacgctgcttgagcgttacaacattgataccttcggcctt
aacgccgtggtgattggcgcatcgaatatcgtcggtcgcccaatgagcatggaactgctg
ctggcaggttgcaccactaccgtgacccaccgtttcactaaaaatctgcgtcaccacgta
gaaaatgccgatctactgatcgttgccgtcggcaagccgggctttattcctggtgactgg
atcaaagaaggcgcaattgtgattgatgtcggcatcaaccgtctggaaaatggcaaagtt
gtgggcgacgtcgtgtttgaagacgcggctaaacgcgcctcatacattacgcctgttccg
ggcggcgttggcccgatgacggttgccacgctgattgaaaacacgctacaggcgtgcgtt
gaatatcatgatccacagggtgagtaa

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