Escherichia coli O17 K52 H18 UMN026 (ExPEC): ECUMN_0034
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Entry
ECUMN_0034 CDS
T00831
Symbol
carB
Name
(GenBank) carbamoyl-phosphate synthase large subunit
KO
K01955
carbamoyl-phosphate synthase large subunit [EC:
6.3.5.5
]
Organism
eum
Escherichia coli O17:K52:H18 UMN026 (ExPEC)
Pathway
eum00240
Pyrimidine metabolism
eum00250
Alanine, aspartate and glutamate metabolism
eum01100
Metabolic pathways
eum01240
Biosynthesis of cofactors
Module
eum_M00051
De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:
eum00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
ECUMN_0034 (carB)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
ECUMN_0034 (carB)
Enzymes [BR:
eum01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
ECUMN_0034 (carB)
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Gene cluster
GFIT
Motif
Pfam:
CPSase_L_D2
CPSase_L_D3
MGS
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
ATPgrasp_Ter
ATP-grasp_4
CoA_binding_2
ATP-grasp_5
SmpA_OmlA
Motif
Other DBs
NCBI-ProteinID:
CAR11257
UniProt:
B7N7Q7
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All DBs
Position
35137..38355
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AA seq
1072 aa
AA seq
DB search
MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEM
ADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATA
DAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGSGGG
IAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAM
GIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEM
NPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIP
RFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEA
LTKIRRELKDAGAERIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVG
ITGLNADFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDT
AYMYSTYEEECESNPSDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVNC
NPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPV
IGTSPDAIDRAEDRERFQHAVERLKLKQPANATVTTIEMAVEKAKEIGYPLVVRPSYVLG
GRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEH
IEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIE
VNPRAARTVPFVSKATGVPLAKVAARVMAGKTLAEQGVTKEVIPPYYSVKEVVLPFNKFP
GVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLA
AKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRR
AIEDSRVIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK
NT seq
3219 nt
NT seq
+upstream
nt +downstream
nt
atgccaaaacgtacagatataaaaagtatcctgattctgggtgcgggcccgattgttatc
ggtcaggcgtgtgagtttgactactctggcgcgcaagcgtgtaaagccctgcgtgaagag
ggttaccgcgtcattctggtgaactccaacccggcgaccatcatgaccgacccggaaatg
gctgatgcgacctacatcgagccgattcactgggaagtggtacgcaagattattgaaaaa
gagcgcccggacgcggtgctgccaacgatgggcggtcagacggcgctgaactgtgcgctg
gagctggaacgtcagggcgtgttggaagagttcggcgtcaccatgattggtgccactgcc
gatgcgattgataaagcagaagaccgccgtcgtttcgacgtagcgatgaagaaaattggt
ctggaaaccgcgcgttccggtatcgcacacacgatggaagaagcgctggcggttgccgct
gacgtgggcttcccgtgcattattcgcccatcctttaccatgggtggtagcggtggcggt
atcgcttataaccgcgaagagtttgaagaaatttgcgcccgcggtctggatctctctccg
accaaagaactgctgattgatgagtcgctgatcggctggaaagagtacgagatggaagtg
gtgcgtgataaaaacgacaactgcatcatcgtctgctctatcgaaaacttcgatgcaatg
ggcatccacaccggtgactccatcactgtcgcaccagcccaaacgctgaccgacaaagaa
tatcaaatcatgcgtaacgcctcgatggcggtgctgcgtgaaatcggcgttgaaaccggt
ggttccaacgtccagtttgcggtgaacccgaaaaacggtcgcctgattgttatcgaaatg
aacccgcgcgtgtcgcgttcttcggcgctggcgtcgaaagccactggtttcccgattgcc
aaagtggcggcgaaactggcggtgggttacaccctcgacgagctgatgaacgacatcacc
ggcgggcgtactccggcctccttcgagccgtccatcgactacgtggtcaccaaaattcct
cgcttcaacttcgagaaattcgccggggcgaacgaccgtctgaccactcagatgaaatcg
gttggcgaagtgatggcgattggtcgcacgcagcaggaatccctgcaaaaagcgctgcgc
ggcctggaagtgggcgcgaccggcttcgatccgaaagtgagtctcgacgacccggaagcg
ctgactaaaatccgccgcgagctgaaagacgctggcgcagagcgtatctggtatatcgcc
gatgctttccgcgcgggcctgtccgtagacggcgtcttcaacctgaccaacattgaccgc
tggttcctggtacagattgaagagctggtgcgtctggaagagaaagtggcggaagtgggc
atcactggcctgaacgctgacttcctgcgccagttgaaacgcaaaggctttgccgacgcg
cgtctggcaaaactcgcgggcgtgcgtgaagcagaaatccgtaagctgcgtgaccagtat
gacctgcacccggtttacaagcgcgtggatacctgtgcggcagagttcgctaccgacacc
gcttatatgtactccacttatgaagaagagtgcgaatccaacccatctgaccgtgaaaaa
atcatggtcctcggcggcggcccgaaccgtatcggtcagggtatcgaattcgactactgt
tgcgtacacgcctcactggcgctgcgcgaagacggttacgaaaccattatggttaactgt
aacccggaaaccgtctccactgattacgacacttccgaccgcctctacttcgagccggta
actctggaagacgtgctggaaattgtgcgtattgagaagccgaaaggcgttatcgtccag
tacggcggtcagaccccgctgaaactggcgcgcgcgctggaagctgctggcgtaccggtt
atcggtaccagcccggatgccatcgaccgtgcggaagaccgtgaacgcttccagcatgcg
gttgagcgtctgaaactgaaacaaccggcgaacgccaccgttaccaccatcgaaatggcg
gttgagaaagcgaaagagattggctacccgctggtggtgcgtccgtcttacgttctcggc
ggtcgggcgatggaaatcgtctatgacgaagctgacctgcgtcgctacttccagacagcg
gtcagcgtatctaacgatgcgccagtgttgctggaccacttccttgatgacgcagtagaa
gttgacgtggatgctatctgcgacggcgaaatggtgctgattggcggcatcatggagcat
attgagcaggcgggcgtgcactccggtgactccgcatgttcgctgccagcctacacctta
agtcaggaaattcaggatgtgatgcgccagcaggtgcagaaactggccttcgaattgcag
gtacgcggcctgatgaacgtgcagtttgcggtgaaaaacaacgaagtctacctgattgaa
gttaacccgcgtgcagcgcgtaccgttccgttcgtctccaaagccaccggcgtaccgctg
gcgaaagtggcggcgcgcgtgatggcaggcaaaacgctggccgagcagggcgtaaccaaa
gaagttatccctccgtactactcggtgaaagaagtggtgctgccgttcaataaattcccg
ggcgttgacccgctgttagggccagaaatgcgctctaccggggaagtcatgggcgtgggc
cgcaccttcgctgaagcgttcgccaaagcgcagctgggcagcaactccaccatgaagaaa
cacggtcgtgcgctgctttccgtgcgcgaaggcgacaaagaacgcgtggtggacctggcg
gcaaaactgctgaaacagggcttcgagctggatgcgacccacggcacggcgattgtgctg
ggcgaagcaggcattaatccgcgtctggtgaacaaggtgcatgaaggtcgtccgcacatt
caggaccgtatcaagaatggcgaatatacctacatcatcaacaccacctcaggccgtcgt
gcgattgaagactcccgcgtgatccgtcgcagtgcgctgcaatataaagtgcattatgac
accaccctgaacggtggtttcgctaccgcgatggcgctgaatgccgatgcgactgaaaaa
gtaatttcggtgcaggaaatgcacgcgcagatcaaataa
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