Felis catus (domestic cat): 101088949
Help
Entry
101088949 CDS
T02385
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101088949 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
fca03032
]
101088949 (TOP2B)
03036 Chromosome and associated proteins [BR:
fca03036
]
101088949 (TOP2B)
Enzymes [BR:
fca01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
101088949 (TOP2B)
DNA replication proteins [BR:
fca03032
]
Eukaryotic type
DNA Topoisomerases
101088949 (TOP2B)
Chromosome and associated proteins [BR:
fca03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
101088949 (TOP2B)
Centrosome formation proteins
Centriole proteins
101088949 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
Motif
Other DBs
NCBI-GeneID:
101088949
NCBI-ProteinID:
XP_023116392
EnsemblRapid:
ENSFCTG00005008783
LinkDB
All DBs
Position
C2:complement(141784815..141850039)
Genome browser
AA seq
1621 aa
AA seq
DB search
MAKAGGGGGAGAGGNGALTWVTLFDQNNAAKKEESETANKNDSSKKLSVERVYQKKTQLE
HILLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKN
MTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGG
RNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQP
DLSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDE
TGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVV
KKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKA
ASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTE
GDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKS
YDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKAS
KNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYA
GPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINK
ELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGE
QALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLSRLLFPAV
DDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLD
GLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLE
PMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMV
LFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQG
KITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPD
FNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQ
EREDILAGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASKKLLKRKK
GDLDTTAVKVEFDEEFSGTPVEGTGEEALIPSAPVNKGPKPKREKKEPGTRVRKTPTSSG
KSTAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDA
DDDEDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSSHDKKGQD
FGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDT
TAKPKRTPKQKKVETVNSDSDSEFGIPKKSTPPKGKGRGAKKRKASGSENEGDYNPGRKT
SKTPSKKMKKTSFDQDSDVDIFPSDFTSEAPSLPRSGRARKEVKYFAESDDEEDVDFAMF
N
NT seq
4866 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcggcggcgcgggagccggcggcaacggggcactgacctgg
gtgactctttttgatcagaacaatgctgcaaaaaaagaagagtcagaaactgcaaacaaa
aatgattcttcaaagaagttgtctgttgagagagtgtatcaaaaaaagacacaacttgaa
catattctccttcgtcctgatacgtatattgggtcagtggagccattgacacagctaatg
tgggtatatgatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggttta
tacaagatctttgatgaaattttggttaatgcagctgacaataaacagagggataagaat
atgacctgtattaaagtttctattgatcctgaatctaacattataagcatttggaataat
gggaaaggcattccagtagtagaacacaaagtagagaaagtttatgttcctgcattaatt
tttggacagcttttaacatccagtaactatgatgatgatgagaaaaaagtaacaggtggt
cgcaatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagagact
gcttgcaaagaatacaagcatagttttaagcagacatggatgaataacatgatgaaaact
tctgaagccaaaattaaacattttgatggtgaagattacacatgcataacattccaacca
gatctgtctaaatttaagatggaaaaacttgacaaggatattgtggccctcatgaccaga
agagcttatgatttggctggttcatgcaaaggggtcaaggtcatgtttaatggaaagaaa
ttgcctgtaaatgggtttcgcagttatgtagatctttatgtgaaagacaaattggacgaa
actggagtggccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctc
acactgagtgaaaagggattccagcaaatcagctttgtaaatagtattgcgacaacaaaa
ggtggacgtcatgtggattacgtagtagatcaagttgttggtaaactgattgaagtagtt
aagaaaaagaacaaagctggggtatcagtaaaaccatttcaagtaaaaaaccatatatgg
gtttttattaattgccttatcgaaaatccaacttttgattctcagacgaaagaaaacatg
actctgcagcccaaaagttttgggtccaaatgtcaactgtcagaaaaattttttaaagca
gcctctaactgtggcattgtagaaagtattctgaactgggtgaaatttaaggctcagact
cagctgaacaagaagtgttcatcagtaaagtatagtaaaatcaaaggtattcccaagctg
gatgatgctaatgatgctggtggcaaacattccctggagtgtacattgatactaacagag
ggagactctgccaagtcgctggctgtgtctggattaggtgtgatcgggcgagacagatac
ggagtctttccacttaggggaaaaattcttaacgtccgagaagcttcccataaacagatc
atggaaaatgcagaaataaacaatattatcaaaatagttggtctacagtacaagaaaagt
tacgatgatgcagaatctctgaaaactttacgctatgggaagattatgattatgactgat
caggatcaagatggttctcacataaaaggcctgcttattaatttcatccatcacaattgg
ccatcacttttgaagcatggttttcttgaagagttcattactcctattgtaaaggctagc
aaaaataagcaggaactttccttctatagtattcctgaatttgacgagtggaaaaaacat
atagaaaaccagaaagcctggaaaataaagtactacaaaggtttgggtaccagtacagct
aaagaagcaaaggaatattttgctgatatggaaaggcaccgcatcttgtttagatatgct
ggccctgaagatgatgctgccattactttggcattcagtaagaagaagattgatgacaga
aaagaatggttaacaaattttatggaagatcggagacagcgtaggttacatggcttacca
gagcaatttttgtatggtacagcaacaaagcatttgacttacaatgatttcatcaacaaa
gaattgattctcttctcaaactcagacaatgaaagatctataccatctcttgttgatggc
tttaaaccaggccaacgtaaagttttatttacttgtttcaagaggaatgataaacgtgaa
gtaaaagttgcccagttggctggatctgttgctgagatgtctgcttatcatcatggagag
caagcattgatgatgactattgtgaatttggctcagaactttgtgggaagtaacaacatt
aacttgcttcagccaattggtcagtttggaactcggcttcatggtggcaaagatgctgca
agccctcgttatattttcacaatgttaagctctttatcaagactgctttttcctgctgtg
gatgacaacctgcttaaattcctttatgatgataatcaacgtgtagagcctgagtggtat
attcctataattcccatggttttaataaatggtgctgagggcattggcactggatgggct
tgtaaactacccaactatgatgctagggaaattgtgaacaacgtcagacgaatgctagat
ggcttggatcctcatcctatgcttccaaactacaaaaactttaaaggaacgatccaagag
cttggtcaaaaccaatatgcagtcagtggtgaaatatttgtggtggatagaaacacagta
gagattacagagcttccagttagaacttggacacaggtatacaaagaacaggttttggaa
cctatgctaaatggaacagataaaacaccagcattaatttctgattacaaagaatatcat
actgatacaactgtgaaatttgtggtgaaaatgactgaagagaagctagcacaagcagaa
gctgctggattacataaagtttttaaacttcaaactactcttacttgtaattccatggta
ctctttgatcatatgggatgtctcaagaaatatgaaactgtgcaagacattttgaaagaa
ttctttgatttacgattaagttattacggtttacgtaaggagtggcttgtaggaatgttg
ggagcagaatctacaaagcttaacaatcaagcccgtttcattttagagaagatacaggga
aaaattaccatagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggt
tatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaa
gaaacacaaaaccagcatgatgatagttcctctgattcaggaactccttcaggccccgat
tttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactg
attaaacagagagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatctccttca
gatctttggaaagaagatttagcagcatttgttgaggaactggataaagtggaggcacaa
gaacgagaagatattctggctggaatggctgggaaagcaataaaaggtaaagttggcaaa
cctaaggtgaagaaacttcagttggaagagacaatgccttccccttatgggagaagaata
gttcctgaaattactgctatgaaggcagatgccagcaaaaagttgctgaagaggaaaaag
ggtgatctcgataccacagcagtaaaagtagaatttgatgaagaattcagtggaacacca
gtagagggtacaggagaagaggcattgatcccgtcagctcctgtaaataaaggtcccaaa
cccaaaagggagaaaaaggagcctggtaccagggtgagaaaaacacctacatcatctggt
aaatccactgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaagtca
gaaagtgacttggaagaaacagagcctgtggttattcccagagattctttgcttaggaga
gcagctgctgaaaggcctaagtacacgtttgacttctcagaagaggaggatgatgatgct
gatgatgatgaggacaataatgatttagaggaattgaaagtgaaagcatctcccataaca
aatgatggggaagatgaatttgttccttcagatggcctagataaagatgaatatacattt
tcacctggcaaatcaaaagctactccagaaaaatcttcacatgacaaaaaaggtcaagat
tttgggaatctcttctcatttccttcatactctcagaagtcagaagatgattcagctaaa
tttgacagtaatgaagaagattctgcctctgttttttcaccatcgtttggtctgaaacaa
acagataaagttccaagtaaaacagtagctgctaaaaagggaaaaccatcttcagataca
actgctaagcccaagagaacccctaaacagaagaaagtagagactgtaaactctgactca
gattcagaattcggcattccaaagaagagtacacccccaaaaggtaaaggccgaggagca
aagaaaaggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaaaca
tccaaaacaccaagcaagaaaatgaagaaaacctcttttgatcaggattcagatgtggac
atcttcccatcagatttcacttctgaagcaccttctctgccacggagcggtcgggctagg
aaagaagtaaaatattttgcagagtccgatgatgaagaagatgttgattttgcaatgttt
aattaa
DBGET
integrated database retrieval system
