Hyphomicrobium denitrificans 1NES1: HYPDE_31678
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Entry
HYPDE_31678 CDS
T02646
Name
(GenBank) alpha-isopropylmalate/homocitrate synthase family transferase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
hdt
Hyphomicrobium denitrificans 1NES1
Pathway
hdt00290
Valine, leucine and isoleucine biosynthesis
hdt00620
Pyruvate metabolism
hdt01100
Metabolic pathways
hdt01110
Biosynthesis of secondary metabolites
hdt01210
2-Oxocarboxylic acid metabolism
hdt01230
Biosynthesis of amino acids
Module
hdt_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hdt00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
HYPDE_31678
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HYPDE_31678
Enzymes [BR:
hdt01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
HYPDE_31678
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Motif
Pfam:
HMGL-like
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AGK58010
UniProt:
N0BD23
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Position
complement(1809409..1811028)
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AA seq
539 aa
AA seq
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MSKERLYLFDTTLRDGAQTTGVDFSLEDKRRLMHVLDELGVDYIEGGYPGANATDSEFFT
SRPELKSARFTAFGMTKRAGRSVSNDPGLQAILQSSADSICLVAKSSDYQVRVALGISKE
ENLECVEQSVRAVVETQREAMIDCEHFFDGYKSNRDYALEVAKTAFQAGARWVVLCDTNG
GTLPHEIERIVADVAKHVPGKNLGIHTHNDTENAVANTLMAVRAGCRQIQGTLNGLGERC
GNANLTSIIPTLLLKSEFADAFATSVTPEKLRTLTHASRVLDEVLNEAPDRHAPYVGESA
FATKAGIHASALIKAPETYEHVPPESVGNERRILVSKQGGRSSLTAALERFGLPSDKEDA
RVQALLDEIKSREDQGYSYEAAEASFELLARRSLASVPRFFSVDSFRVTVERNRALNGSG
THAQAVVTVSIAGEHDPLVSVGEGNGPVNALDKALRSDLGRYQKHIDHVELVDYKVRILT
HTPNGGTDAVTRVLVESHDTETGERWTTVGVSTNIIDASFEALLDSINYKLLKDNARVA
NT seq
1620 nt
NT seq
+upstream
nt +downstream
nt
atgagtaaagaacgcctctatctcttcgacacgacgttgcgcgacggcgcgcagacgacc
ggcgtcgatttctcgcttgaagacaagcgccgcctgatgcacgtgctggacgaacttggt
gtcgattatatcgagggcggataccccggcgccaatgcgaccgacagcgagttttttacc
tcgcggccggagttgaagtcggcgcgctttactgcgttcggcatgacgaagcgcgccggg
cgctcggtctcgaacgatccagggctgcaagccattctgcaatcgtctgcggacagcatc
tgccttgtcgccaagtcgtccgattatcaggtacgggtcgcgctcggcatctcgaaggaa
gaaaatctcgagtgcgtggagcagtcggtccgcgctgtcgtcgagacgcagcgcgaggcg
atgatcgactgcgagcacttcttcgacggctataagagcaatcgcgattacgcgttggag
gtcgcgaagacggccttccaggcgggcgcgcgttgggtggttctctgcgacacgaacggc
gggacgctgccgcacgaaatcgagcgcatcgtcgccgatgtcgcgaagcacgtgccgggc
aagaacctcggaattcatacgcacaacgacacggagaacgcggttgccaatacgctgatg
gcggtgcgcgccggatgccggcagatccagggaacgctcaatggcctcggcgagcgctgc
ggcaacgccaatctcacgtcgatcattccgacgctgctgctgaagagcgagtttgccgat
gcgtttgcgaccagtgtcacgcctgaaaaattgcggaccctcactcatgccagccgcgtg
ctcgatgaagttctgaacgaagcgccagaccggcatgccccttatgtgggcgagagcgcc
ttcgcgacaaaggctggtattcacgcgtcggcgttgatcaaggcgccggagacctatgag
cacgtgccgcccgaaagcgtcggcaacgaacggcgtattctggtgtcgaagcagggcggc
cgctcgtcgttgacggcagcgctcgagcgcttcggcctgccgtccgacaaggaagatgct
cgtgtgcaggcgcttctcgatgaaatcaagtcacgtgaggatcaaggttattcctacgaa
gcggcggaagcatccttcgagcttcttgcacgccgctcgctcgccagcgtgccgcgcttc
ttttccgtcgattcatttcgcgtcaccgtcgagcgcaatcgagcgctcaacggtagcggc
acacatgctcaagctgttgtgacagtttcaattgcgggcgagcacgatccgctggtttcg
gtcggagaaggcaacggcccggtcaacgcgctcgacaaggcgctgcgcagcgacctcggc
cgctatcaaaagcatatcgatcacgtggaactcgtggactataaggtccgcattctgacc
cacacgccgaacggcggcaccgatgcggtgacgcgcgtgctcgtcgaaagccacgacacc
gaaacgggtgagcgctggacgacggtcggtgtctcgacgaacatcatcgacgcgagcttc
gaagcgcttctcgacagcatcaactataagcttctgaaagacaacgcgcgcgtcgcgtga
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