Heterocephalus glaber (naked mole-rat): 101704055
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Entry
101704055 CDS
T02812
Symbol
Apc
Name
(RefSeq) APC, WNT signaling pathway regulator
KO
K02085
adenomatosis polyposis coli protein
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04310
Wnt signaling pathway
hgl04390
Hippo signaling pathway
hgl04550
Signaling pathways regulating pluripotency of stem cells
hgl04810
Regulation of actin cytoskeleton
hgl04934
Cushing syndrome
hgl05010
Alzheimer disease
hgl05022
Pathways of neurodegeneration - multiple diseases
hgl05165
Human papillomavirus infection
hgl05200
Pathways in cancer
hgl05206
MicroRNAs in cancer
hgl05210
Colorectal cancer
hgl05213
Endometrial cancer
hgl05217
Basal cell carcinoma
hgl05224
Breast cancer
hgl05225
Hepatocellular carcinoma
hgl05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
101704055 (Apc)
04390 Hippo signaling pathway
101704055 (Apc)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
101704055 (Apc)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101704055 (Apc)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101704055 (Apc)
05206 MicroRNAs in cancer
101704055 (Apc)
09162 Cancer: specific types
05210 Colorectal cancer
101704055 (Apc)
05225 Hepatocellular carcinoma
101704055 (Apc)
05226 Gastric cancer
101704055 (Apc)
05217 Basal cell carcinoma
101704055 (Apc)
05213 Endometrial cancer
101704055 (Apc)
05224 Breast cancer
101704055 (Apc)
09172 Infectious disease: viral
05165 Human papillomavirus infection
101704055 (Apc)
09164 Neurodegenerative disease
05010 Alzheimer disease
101704055 (Apc)
05022 Pathways of neurodegeneration - multiple diseases
101704055 (Apc)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101704055 (Apc)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hgl01009
]
101704055 (Apc)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hgl03036
]
101704055 (Apc)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hgl04812
]
101704055 (Apc)
Protein phosphatases and associated proteins [BR:
hgl01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
101704055 (Apc)
Chromosome and associated proteins [BR:
hgl03036
]
Eukaryotic type
Centrosome formation proteins
Other centriole associated proteins
101704055 (Apc)
Cytoskeleton proteins [BR:
hgl04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
101704055 (Apc)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Arm_APC_u3
APC_basic
EB1_binding
APC_r
APC_u5
APC_rep
APC_u15
APC_u14
APC_u9
SAMP
APC_N_CC
Arm
APC_u13
APC_15aa
Suppressor_APC
Sec7-like_HUS
Motif
Other DBs
NCBI-GeneID:
101704055
NCBI-ProteinID:
XP_004841838
LinkDB
All DBs
Position
Un
AA seq
2857 aa
AA seq
DB search
MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM
ASSGQIDLLERLKELNLDSSSFPGVKLRSKMSLRSYGSREGSISSRSGECSPVPMGSFPR
RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL
QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAA
EAERSSQNKHEAGLHEAERQNEGQGVAEINMAPSGSQGSATRMDHETASVLSSSTHSAPR
RLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLLHG
NDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWE
WQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGRKATRGISSQEL
GQGLSGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKG
CMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKEST
LKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSS
LIATNEDHRQILRDNNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAV
SMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAEL
DAQHLSETFDNIDNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDSFNTGNMTVLSP
YLNTTVLPSSSSSRGSLDSSRSEKDRSLEREREIGLSSYHPATENPGTSSKRGLQISTTA
VQIAKVMEEVSVIHTSQEDRNSGSTTELHCVTDERNAIRRSSAAHTHSNTYNFTKSENSN
RTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADL
AHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSE
QRQSRSQNTTYPVYTESNDDKHLKFQPHFGQQECVSPYRSRGTNGSEANRVGSSHGINQN
VNQSLCQEDDYEDDKPTNYSERYSEEEQHEEERPTNYSIKYNEEKHHVDQPIDYSLKYAT
DISSSQKPSFTFSKSSSVQSSKTEHISSSSETTSTPSSNTKRQNQVHPNSAQSISGQTQK
ATTCKVPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDETGCDQTTQEADSAGTLKIA
EIKESSVTRATEDPANEVSTASQHVRTKSSRLQASGLSSESTRHKAVEFSSGAKSPSKSG
AQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPD
SPGQTMPPSRSKTPPPPPQTVQSKREVPKNKVPPVEKRENGPKQAAVNEAVQRVHVLPDT
DTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETEPEQPEES
NENQEKEAEKHIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKLAQTASKLPPPV
ARKPSQLPVYKLLPSQNRLQTQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESP
PNELAVGEGARAGTQSSEFENRDTIPTEGRSTDEVQRGKPSSIPMPELDDNKTEEGDILA
ECINSAMPKGKSHKPFRVKKIMDQVQQASVSSPGTNKNQIDSKKKKPTSPVKPMPQNTEC
RTRARKNTDSKNSLNADRTFSDNKDSKKQNLKNNSKDLNDKLPNNEDRVKGSFAFDSPHH
YTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKENKDSEAKVTSHTELTSNQQ
SANKTQAVTKHSVNRGQSKPLPQKPPSFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSR
NSSLSSLSDIDQENNNKENEPIKETEPPDSQGGPSKPQASGYAPKSFHVEDTPVCFSRNS
SLSSLSIDSEDDLLQECISSAMPKKKRPSRLKGDNEKHSPRNMGSLLAEDLTLDLKDIQR
PDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAACLSRQASSDSDSILSLKSGISLGS
PFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKMESENKGIKGGKKVYKSLITGKVRSN
SEISSQMKQPLQTNMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEAQT
ATTSPRGAKPSVKSELSPVTRQTSQIGGSNKGSSRSGSRDSTPSRPAQQPLSRPMQSPGR
NSISPGRNGISPPNKLSQLPRTSSPSTVSTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSK
NTSSITRSESASKGLNQMSNSNGSNKKVELSRMSSAKSSGSESDRSERPVLVRQSTFIKE
APSPTLRRKLEESASFESLSPSSRPDSPTRSQAQTPVLSPSLPDMSLPTHSSLQAGGWRK
LPPNLSPTIEYNDGRPTKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRR
TGSSSSILSASSESSEKAKSEDEKHVYSISGTKQTKENQVSTRGTWRKIKESELSPTNMT
SPTTSSGAINGAESKTLIYQMAPAVSKTEDIWVRIEDCPINNPRSGRSPTGNTPPVIDGV
SEKGNPSIKDSKDNQGKQNVGNGSAPMHTTGLENRLNSFIQVDAPDQKGTETKSGQSNPV
PTAETSENSIAERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIP
TPVNTNTKKRDSKTDSTESNGTQSPKRHSGSYLVTSV
NT seq
8574 nt
NT seq
+upstream
nt +downstream
nt
atggctgcagcttcatatgatcagttgttaaagcaagttgaggcactgaagatggagaac
tcaaatcttcgacaagagctagaagataattccaaccatcttacaaaactggaaactgag
gcatctaatatgaaggaagtacttaaacaactacaaggaagtattgaagatgaagctatg
gcttcttctggacaaattgacttattagagcgtcttaaagaacttaatttagatagcagc
agtttccctggagtaaaactacgatcaaaaatgtcgctccgttcttacggaagccgggaa
ggatccatatcgagtcgttcaggagaatgcagccctgttcctatggggtcatttccaaga
agagggtttgtaaatggaagcagagaaagtactggatatttagaagaacttgagaaagag
agatcattactccttgctgatcttgacaaagaagaaaaggaaaaagactggtattatgct
caacttcagaatctcactaaaagaatagatagtcttcctttaactgaaaatttttcctta
caaacagatatgaccagaaggcaattggaatatgaagcaaggcagatcagagttgcaatg
gaagaacagctgggcacatgccaggatatggaaaaacgagcacagcgaagaatagccaga
attcagcaaatagaaaaggacatacttcgtatacgacaacttttacagtcccaagcagca
gaagcagagaggtcatctcagaacaaacatgaagctggcttacacgaggctgagcggcag
aatgaaggtcaaggagtggcagagatcaacatggcaccttctggtagtcagggttcagct
acacgaatggaccacgaaacagccagtgttttgagttctagtacacactctgctcctcga
aggctgacaagtcatctgggaaccaaggtggaaatggtgtattcattgttgtcaatgctt
ggtactcatgataaggatgatatgtcacgaactttgctagctatgtctagctcccaagac
agctgtatatccatgcgacagtctggatgtcttcctctcctcatccagcttttacatggc
aatgacaaagactctgtattgttgggaaattcccggggcagtaaagaggctcgggccagg
gccagtgcagccctccacaacatcattcactcacagcctgatgacaagagaggcaggcgt
gaaatccgagtccttcatcttttggaacagatacgagcttactgtgaaacctgttgggag
tggcaggaagcccatgaacaaggcatggaccaggacaaaaatccaatgcccgctcctgtt
gaacatcagatctgtcctgctgtatgtgttctgatgaaactttcatttgatgaagagcat
agacatgcaatgaatgaacttggtaggaaggctacccggggcatttcatcacaggagcta
gggcaggggctttcagggggactacaggccattgcagaattattgcaagtggactgtgaa
atgtatgggcttactaatgaccactacagtattactttaagacgatatgctggaatggct
ttaacaaacttgactttcggagatgtagccaacaaggctacactctgttctatgaagggc
tgcatgcgagcacttgtggcccaactaaaatctgaaagtgaagacttacaacaggttatt
gcaagtgttttgaggaatttgtcctggcgagcagatgtaaatagtaaaaagacattgaga
gaagttggaagtgtgaaagcattgatggaatgtgctttggaagttaaaaaggaatcaacc
ctcaaaagtgtattgagtgccttatggaatttgtcagcacattgcactgagaataaagct
gatatatgtgctgtagatggtgcacttgcatttttggttggcactctgacttaccggagc
cagacaaacactttagccatcattgaaagtggaggtgggatattacggaatgtgtccagc
ttgatagcaacaaatgaggaccacaggcaaatcctaagggataacaactgcctacaaacc
ttattacaacacttgaaatctcacagtttaacaatagtcagtaatgcatgtggaactctg
tggaatctctcggcaagaaatcctaaagaccaggaagcattatgggacatgggggcagtc
agcatgctcaagaacctcattcattcaaagcacaaaatgattgctatgggaagtgctgca
gctttaaggaatctcatggcaaatagacctgcaaagtataaagatgccaatattatgtct
cctggttcaagcttgccatctcttcatgttaggaaacaaaaagccctagaagcagaatta
gatgctcagcatttatcagaaacttttgacaatattgataatttaagtcccaaggcatct
catcgtagtaagcagagacacaagcaaagtctttatggtgactatgtttttgatactaat
cgacatgatgataataggtcagacagttttaatactggaaacatgactgttctttctcca
tacttgaatactactgtgttacccagctcttcttcatcaaggggaagtttagatagttct
cgttctgaaaaagacagaagtttggagagagaacgagagattggcctaagcagttaccat
ccagcaacagaaaacccaggaacctcttcaaaacgaggtttgcagatatctaccactgca
gtccaaattgccaaagttatggaagaagtatcagtcattcatacctcccaggaagataga
aattctggttccaccactgaattacattgtgttacagatgagaggaatgcaataagaaga
agctctgctgcccacacccattcaaacacatacaatttcactaaatcagaaaattcaaat
aggacatgttctatgccttatgccaagctggaatataagagatcttcaaatgatagttta
aatagtgtcagtagtagtgatggttatggtaaaagaggtcaaatgaaaccctcaattgaa
tcatattctgaagatgatgaaagtaaattttgcagttacggtcaatatccggctgaccta
gcccataaaatacatagtgcaaatcacatggatgataatgatggagagctggatacacca
ataaattatagccttaaatactcagatgagcagctgaactctggaagacagagtccttca
cagaatgaaagatgggcaagacccaaacacataatagaagatgaaataaaacaaagtgag
caaagacaatcaaggagtcaaaataccacttaccctgtatatactgagagcaatgatgat
aagcacctcaagttccaaccacatttcggacagcaggaatgtgtttccccatacaggtcc
aggggaactaatggctctgaagcaaaccgagtgggttcaagtcatggaattaaccaaaat
gtaaaccagtctttgtgtcaggaagatgactatgaagatgataagccaaccaactatagt
gaacgttactctgaggaagaacaacatgaagaagagagaccaacaaattatagcataaaa
tataatgaagagaaacatcatgtggatcagcctattgattatagtttaaaatatgccact
gacatttcttcctcacagaaaccatcatttacattctcaaagagttcatctgtacagagc
agtaaaactgaacacatctcgtcaagcagtgagactacatccacaccttcctctaatacc
aagaggcagaatcaggtgcatccaaattcagcacaaagtataagtggtcagactcaaaaa
gccaccacttgcaaagtcccctctatcaaccaagaaacgatccagacttactgtgtagaa
gacaccccaatatgtttttcaaggtgtagttccttatcatctttgtcatcagctgaagat
gaaacaggatgtgatcagacaacacaagaagcagattctgctggtactctgaaaatagca
gaaataaaagagagcagtgtgactagagcaacggaagaccctgcaaatgaagtttcaaca
gcgtcacagcatgttagaaccaaatccagcagactccaggcctctggtttatcttcagaa
tcaaccaggcacaaagccgttgaattttcttcaggggcaaaatctccctccaaaagtggt
gctcagacacccaaaagtccaccagagcactatgttcaggagactccactcatgtttagc
agatgtacttctgtcagttcacttgatagttttgagagtcgttccatagccagctctgtt
cagagtgaaccatgcagtgggatggtaagtggcattataagccccagtgaccttccagat
agccctggacaaaccatgccaccaagcagaagtaaaacccctccacctcctccccaaaca
gttcaaagtaagcgagaggtacctaaaaataaagtgcctcctgttgaaaagagagaaaat
ggacctaagcaagctgctgtaaatgaggctgttcagagggtccatgtccttccagatact
gatactttattgcattttgccacagaaagtactccagatggattttcttgttcatctagc
ctgagtgccctgagccttgatgagccatttatacagaaagatgtggagttaagaataatg
cctccagttcaggaaaatgacaatggaaatgaaacagaaccagagcagcctgaagaatca
aatgaaaaccaggaaaaagaggcagaaaaacacattgattctgaaaaagatctgttagat
gactcagatgatgatgatatcgaaattttagaagaatgtattatttctgccatgccaaca
aagtcatcacgcaaagccaaaaagctagcccagactgcttcaaaattacctcctcctgtt
gcaaggaaaccaagtcaactgcctgtgtacaaacttctgccatcacaaaacagattgcag
acacaaaagcatgttagtttcacaccaggagacgatatgccacgagtgtattgtgtagaa
gggacacctataaacttttccacagctacatcactaagtgatctaacaatagaatctcct
ccaaatgagttagctgttggtgaaggggccagagcagggacacagtccagtgaatttgaa
aaccgggataccattcctacagaaggcagaagtacagatgaggttcagagagggaaaccc
tcatctatacctatgcccgagttggatgacaataagacagaggaaggtgatattcttgca
gaatgcattaattctgctatgcccaaaggaaaaagtcacaagcctttccgtgtgaaaaag
ataatggaccaggtccaacaagcatctgtgtcttcacctggaactaacaaaaatcaaata
gatagtaagaaaaagaagcctacttcaccagtaaaacctatgccacaaaataccgaatgt
agaacacgtgcaaggaagaatacagactcaaaaaatagtttaaatgctgaccgaactttc
tcagacaacaaagattcaaagaaacagaacttgaaaaataattccaaggatttaaatgat
aagctaccaaataatgaagatcgagtcaaaggaagttttgcttttgattcacctcatcac
tacacccccattgaaggaacaccttactgtttttcacgaaatgattctttgagttctcta
gattttgatgatgatgatgttgacctttctagagaaaaggctgaactgaggaaggggaaa
gaaaataaggactcagaagctaaagttaccagtcacacagaactaacctcaaaccaacaa
tcagctaataaaacacaggctgttacaaaacattcagtaaatcgaggtcagtctaaacct
ttaccacagaagccaccctctttcccccagtcatccaaagacataccagatagaggggca
gcaactgatgaaaaattacagaattttgctattgaaaatactccagtgtgcttttctcgt
aattcctccctgagttctctcagtgacattgaccaggaaaacaacaacaaagaaaatgaa
cccatcaaagagactgagcctcctgactcacaaggaggaccgagtaaacctcaggcgtca
ggttatgctcctaaatcatttcatgttgaagatacccctgtttgtttttcaagaaatagt
tctctcagttctctcagtattgattctgaagatgacctcttgcaggagtgtataagttct
gcaatgccaaaaaagaaaaggccctcaagactcaagggtgataatgaaaagcacagtccc
agaaacatgggtagcttattagctgaagatttgacccttgatttgaaagatatacagaga
ccagattcagaacatggtttatcccctgattcagaaaattttgattggaaagctattcaa
gaaggtgcaaattccatagtgagtagtttacatcaagctgctgctgcctgcttatctaga
caagcttcatctgattctgattctatcctttcattgaaatcaggaatctctctgggatca
ccttttcatcttacacctgatcaagaagaaaaacccttcacaagtaataaaggcccacga
attctcaaacctggggagaaaagtacattagaaactaaaaaaatggaatctgaaaataaa
ggaatcaaaggaggaaaaaaagtttataaaagtttgattactggaaaagttcgatctaat
tcggaaatttcaagccaaatgaaacagcctcttcaaacaaatatgccttcaatctctcga
ggtaggacaatgattcatattcccggagttcgaaatagttcctcaagtacaagtcctgtt
tctaaaaaggggccacccttgaagactccagcctccaaaagccctagtgaagctcagaca
gccaccacttctcctagaggagccaagccatcggtgaaatcagaattaagccctgttacc
aggcagacttcccaaataggtgggtcaaataaagggtcttctaggtcaggatctagagat
tccactccttcaagacctgcacagcaaccattaagtagacctatgcagtctccagggcga
aactcaatttcccctggtagaaatggaataagtcctcctaacaaattatctcaactgccc
aggacatcgtcccccagtactgtttcaactaagtcctcgggttctgggaaaatgtcatac
acatccccaggcagacagatgagccaacaaaaccttaccaaacaaacaggcttatccaag
aataccagtagtatcaccagaagtgagtctgcctctaagggactaaatcagatgagtaat
agcaatggatccaataaaaaggtggaactttcccgaatgtcttcagctaagtcaagtgga
agtgaatctgatagatcagagagacctgtcttagtacgacagtctactttcatcaaagaa
gctccaagcccaaccctgagaagaaaactggaagaatctgcttcatttgaatctctttct
ccatcttctagaccagactctcccactaggtcccaggcacaaacaccagttttaagtcct
tcccttcctgatatgtctctacccacacactcatctcttcaggctggtggatggcgaaaa
ctcccacctaatctcagtcccactatagagtataatgatggaagaccaacaaagcgtcat
gacatagcacgctcccattctgaaagtccttccagacttccaatcaataggtcaggaacc
tggaagcgtgagcacagcaaacattcatcctcccttcctcgagtaagcacttggagaaga
actggaagttcatcttcaattctttcggcttcatcagagtccagtgaaaaagcaaaaagt
gaggatgaaaaacatgtgtactctatttcaggaaccaagcaaactaaagaaaaccaagta
tccacaagaggaacatggagaaaaataaaagaaagtgaactttctcccacaaatatgact
tctccaaccacttcctcaggtgctataaatggtgctgaatcaaagaccctgatttatcaa
atggcacctgctgtttctaaaacagaagatatttgggtgagaattgaggactgtcctatt
aacaaccctagatctggaagatctcctacaggtaatactcccccagtgattgatggtgtc
tcagaaaagggaaatccaagcattaaagattcaaaagataatcagggaaaacaaaatgtg
ggtaatggcagtgctcccatgcacaccacaggtttggaaaaccgcctgaactcctttatt
caggtggatgccccagaccaaaaaggaacggagacaaaatcaggacaaagtaatcctgtc
cccacagcagagactagtgaaaattctatagcagagcgtaccccattcagttcaagcagc
tccagcaagcacagttcacctagtgggactgttgctgcccgagtgactccttttaattac
aacccaagccccaggaaaagcagtgcagatagcacttcggcccggccatctcagatccca
acaccggtgaataccaacacaaagaaacgagattcaaaaaccgacagcacagaatccaat
ggaactcaaagtcctaagcgccattctgggtcttaccttgtaacatctgtttaa
DBGET
integrated database retrieval system
