KEGG   Heterocephalus glaber (naked mole rat): 101709130Help
Entry
101709130         CDS       T02812                                 

Gene name
Hk1
Definition
(RefSeq) hexokinase 1
  KO
K00844  
hexokinase [EC:2.7.1.1]
Organism
hgl  Heterocephalus glaber (naked mole rat)
Pathway
Glycolysis / Gluconeogenesis
Fructose and mannose metabolism
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Neomycin, kanamycin and gentamicin biosynthesis
Metabolic pathways
Carbon metabolism
HIF-1 signaling pathway
Insulin signaling pathway
Type II diabetes mellitus
Carbohydrate digestion and absorption
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:hgl00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    101709130 (Hk1)
   00051 Fructose and mannose metabolism
    101709130 (Hk1)
   00052 Galactose metabolism
    101709130 (Hk1)
   00500 Starch and sucrose metabolism
    101709130 (Hk1)
   00520 Amino sugar and nucleotide sugar metabolism
    101709130 (Hk1)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    101709130 (Hk1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    101709130 (Hk1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    101709130 (Hk1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    101709130 (Hk1)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    101709130 (Hk1)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    101709130 (Hk1)
Enzymes [BR:hgl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     101709130 (Hk1)
Membrane trafficking [BR:hgl04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    101709130 (Hk1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
UniProt: 
LinkDB All DBs
Position
Un
AA seq 917 aa AA seqDB search
MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLMDIMARFKQEMRNGLSRDYNPTAI
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKKQNVHMESEAYAIPENILH
GSGSQLFDHVAECLGDFMDKREIKDKNLPVGFTFSFPCRQSKIDEGVLITWTKRFKASGV
EGADVVKLLNKAIKRRGDYDANVVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME
ELRHIDMVEGDEGRMCINTEWGAFGDDGALEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFETSDVSAIEKNKEGLQNAKEILTRLG
VEPSDDDCISVQHVCTIVSFRSANLVAATLGAILLRLRDNKGTPRLRTTVGVDGSLYKTH
PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLANFHLT
KEMLMEVKKRMRAEMEAGLRRQTHDKAVVKMLPSFVRSTPDGTEHGDFLALDLGGTNFRV
LLVKIRSGKRRTVEMHNKIYAIPVEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGF
TFSFPCKQTSLDAGILVTWTKGFKATDCVGHDVATLLRDAIKRREEFDLDVVAMVNDTVG
TMMTCAYEEPSCEVGLIVGTGCNACYMEEMKNVEMLEGNEGLMCINMEWGAFGDNGCLDD
IRTEYDRLVDEYSLNSGKQRYEKMISGMYLGEIVRNILIDFTKRGFLFRGQISETLKTRG
IFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAA
VVDKIRENRGLNHLNVTVGVDGTLYKLHPHFSKIMHQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLREEASS
NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt
atgatcgccgcgcagctcctggcctattacttcaccgagctgaaggatgaccaagtcaaa
aagattgacaagtatctctatgccatgcggctctccgatgaaactctgatggatatcatg
gctcgcttcaagcaagagatgaggaatggcctctctcgggattataacccaacagccata
gtcaagatgttgccaacctttgtgaggtccattcctgatggctcagaaaagggagatttc
attgccctggatcttggtgggtcttcttttcgaattctgcgggtgcaagtgaatcacgag
aagaagcagaatgttcacatggagtccgaggcttacgccatcccagagaacattttgcac
ggcagtggaagccagctttttgatcatgttgctgagtgcctgggggacttcatggacaaa
agggagatcaaagacaagaacctacctgtgggcttcacgttttctttcccttgtcggcag
tccaaaatagatgagggcgtcctgatcacctggacaaagaggttcaaagccagcggtgtg
gaaggggcggatgtggtcaagctgctgaacaaagccatcaagcggagaggggactatgat
gccaacgttgtagctgtggtgaatgacactgtagggaccatgatgacctgtggctatgat
gaccagcactgtgaagtcggcctgatcattggcacaggcaccaacgcttgctacatggag
gagctgaggcacattgatatggtggaaggcgacgaggggaggatgtgcatcaacaccgaa
tggggggcctttggggacgacggggccttggaggacatccggactgagttcgacagggag
atagaccggggatccctcaaccctgggaaacagctctttgagaagatggtcagcggcatg
tatctgggagagctggttcggctgatcctggtcaagatggcaaaggaaggcctcctgttt
gaagggcggatcaccccagagctgctcaccagagggaagtttgaaaccagtgacgtgtcg
gccattgaaaagaacaaggaaggcctccagaatgccaaagaaatcctgacccgcctggga
gtggaaccctctgatgatgactgtatttcggtccagcatgtgtgcaccattgtctccttt
cgctcggccaacctggtggctgccacattgggagccatcttgctccgcctgcgagataac
aagggcacacccaggctgaggaccacagttggtgttgacggctctctttacaagacacac
ccacagtattcccgtcgcttccacaagaccctgagacgcctggtacccgactctgacgtg
cgtttcctcctctcggagagcggcagtggcaagggggctgccatggtgactgcggtggct
taccgcctggctgagcagcaccggcagatagaggagaccctggccaacttccacctcacc
aaggagatgctgatggaggtgaagaagaggatgcgagctgagatggaggcggggctgagg
aggcagacccatgacaaggcggtggtcaagatgctgccctccttcgtccggagcacccca
gacgggaccgagcacggtgacttcttggccctggatcttggaggaacgaatttccgtgtc
ctgctggtgaagattcgtagtgggaaaaggagaacagtggaaatgcataacaagatctat
gccattcctgttgaaatcatgcagggtacaggggaagagctgtttgaccacatcgtatcc
tgcatctctgacttcctggactacatggggatcaaaggcccccggatgcctctggggttc
actttctcctttccctgcaagcagacgagcctggatgcgggaatcctggtcacttggacg
aagggctttaaggcaactgactgcgtgggtcatgacgtagccactttactaagggatgca
ataaaaaggagagaggaattcgacctggacgtggtggcgatggtcaatgacacagtgggt
accatgatgacctgcgcttacgaagaacccagctgtgaggttggactgatcgtagggact
ggttgcaatgcctgctacatggaggagatgaagaacgtcgagatgctggaggggaacgag
gggctgatgtgtatcaacatggagtggggcgccttcggggacaacgggtgtctggatgat
atcagaacagagtatgacagattggtggacgaatattctctaaactcggggaaacaaagg
tatgagaagatgatcagcggtatgtacctgggtgaaatcgtccgaaacatcctcattgac
ttcaccaagaggggtttcctcttccgagggcagatctccgagaccctcaagacccggggt
atctttgagaccaaatttctctctcagattgaaagtgaccgattagcgctgctccaggtc
cgggccatcctgcagcagctaggtctgaacagtacatgcgatgacagtatcctcgtcaag
accgtgtgcggggtggtgtcccggagggctgcgcagctgtgtggcgctggcatggctgcc
gtggtggacaagatccgggagaacagagggctgaaccatctgaacgtgaccgtaggagtg
gatgggacgctctacaagcttcatccgcacttctccaaaatcatgcaccaaacggtgaag
gaactgtcgccaaagtgtaatgtgtccttcctcctgtctgaagatggtagcggcaagggg
gcagccctcatcacggccgtgggtgtgcggctccgagaagaagcgagcagctaa

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