Haloferax mediterranei: HFX_0644
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Entry
HFX_0644 CDS
T02129
Symbol
topA
Name
(GenBank) DNA topoisomerase I
KO
K03168
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
hme
Haloferax mediterranei
Brite
KEGG Orthology (KO) [BR:
hme00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
hme03032
]
HFX_0644 (topA)
03400 DNA repair and recombination proteins [BR:
hme03400
]
HFX_0644 (topA)
Enzymes [BR:
hme01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
HFX_0644 (topA)
DNA replication proteins [BR:
hme03032
]
Prokaryotic type
DNA Topoisomerases
HFX_0644 (topA)
DNA repair and recombination proteins [BR:
hme03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
SHIIR (short-homology-independent illegitimate recombination)
Facilitator
HFX_0644 (topA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
zf-C4_Topoisom
Toprim
HHH_5
DNA_pol_lambd_f
Cdd1
HHH
IMS_HHH
DUF4332
HHH_8
DUF1272
HEXIM
Motif
Other DBs
NCBI-ProteinID:
AFK18368
UniProt:
I3R2A8
LinkDB
All DBs
Position
complement(606304..608871)
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AA seq
855 aa
AA seq
DB search
MSRGPELIITEKDNAARRIADILSGETASAERMNGVNVYKWGGKRCIGLSGHVVGVDFPP
EYNDWRDVEPVELISAPVEKHPTQENIVAALRRLARKAGNVTIATDYDREGELIGKEAYE
LVRDVNEDVPVDRVRFSSITKREVTEAFENPDDLDFDLAAAGEARQIIDLVWGAALTRFL
SLSARQLGNDFISVGRVQGPTLKLIVDREREIEAFDPEDYWELFSKLTKDADGAAESFEA
QYFYLDDDGTEAERIWDEEAAESAYETLLDVDAAEVTAVKRRTRTDKPPAPFNTTQFIRA
AGSIGYSAQRAMSIAEDLYTAGYITYPRTDNTVYPDDLDPRELLGAFEGDRRFKEDAKSL
LEQEEIEPTEGDNETTDHPPIHPTGELPSASDLTEDEWDVYELVVRRFFATVAENAVWEH
LRVVAEAAGLSLKANGKRLLEPGYHEVYPYFNSTESFVPDVEEGEALVLSETHLDAKQTQ
PPRRYGQSRLIETMEQMGIGTKATRHDVIQKLYDRGYIESDPPRPTRLARAVVEASEDFA
KLIVSEEMTSQLESDMLAIARGEATLEDVTEESKEMLGDVFEGLMESREELGKQLQDSLK
ADKTVGTCPDCGGDLVVRKSRRGSYFIGCDSYPDCTYTLPLPSTGKPLIMEDACEEHDLH
HIKMLAGRKTFVHGCPLCKAEEADEEDDLIIGSCPECGEGATSEASQGEGGETAEAGGEL
AIKRLRSGSRLVGCTRYPDCDYSLPLPRRGDIEVTDESCEEHDLPELRITYEGDREPWDL
GCPICNYREYQAQQNGEGGSDLESIKGIGAKTAEKLKDAGIEDVKTLKAAEPDDVASRVD
GVGADTVRKWQTAAD
NT seq
2568 nt
NT seq
+upstream
nt +downstream
nt
atgagccgcggcccggaactcatcatcacagagaaggacaacgccgcgaggcgtatcgcc
gacatcctgagcggcgagaccgcctccgcagagcgaatgaacggcgtcaacgtctacaag
tggggtgggaaacgctgtatcggtctgtcaggtcacgtcgtcggcgtggatttcccgccg
gagtacaacgactggcgcgacgtcgagccagtcgaactcatcagtgcgcccgtcgagaaa
cacccgacacaggagaacatcgtcgccgccttgcgacgactcgctcgcaaggccggaaac
gtcaccatcgccacagactacgaccgcgagggtgaactcatcggcaaggaggcgtacgaa
ctcgtccgcgacgtgaacgaggacgtgcccgtcgaccgagttcgattctcctcgattacg
aaacgcgaggtgacagaggcgttcgagaatccggacgacctcgacttcgacctcgccgcc
gccggcgaggcgcgacagattatcgacctcgtctggggggccgcacttacgcgcttcctc
tcgctttcggcccggcaactcggcaacgacttcatctcggtcggacgcgtgcagggaccg
acgctgaaactcatcgtcgaccgcgagcgcgaaatcgaagcgttcgaccccgaggactac
tgggaactgttctctaaactcacgaaggacgccgacggggccgccgagtccttcgaagcc
cagtacttctacctcgacgacgacgggaccgaagccgagcgcatctgggacgaggaggcc
gccgaatcggcctacgagacactcctcgatgtcgatgccgcggaagtcaccgccgtcaag
cgccgcactcgaaccgacaagccgcccgcgccgttcaacaccacccaattcatccgcgcc
gctgggtctatcggctactccgcccagcgggcgatgagcatcgccgaagacctctacacg
gcgggctacatcacctacccgcggaccgacaacacggtctaccccgacgacctcgacccc
cgcgaactcctcggcgcgttcgagggtgaccgtcggttcaaagaggacgcgaagtccctc
ctcgaacaggaggaaatcgaaccgaccgaaggcgacaacgagacgaccgaccacccgccg
attcacccgacgggtgaactcccgtccgcctccgacctcacggaagacgagtgggacgtg
tacgaactcgtcgtccggcgcttcttcgccaccgtggccgagaacgcggtgtgggaacac
ctccgggtcgtcgccgaggccgccggtctctcgctcaaggccaacggtaagcgcctcctc
gaaccgggctaccacgaagtctacccgtacttcaactccaccgaatcgttcgtccccgac
gttgaagagggcgaggcgctcgtgctctccgagacgcatctcgacgcgaagcagacccaa
ccgccgcgtcgctacgggcagtcgcgactcatcgagacgatggaacagatgggtatcggg
acgaaagcgacccgccacgacgtgattcagaagctctacgaccgcggctacatcgagagc
gacccgccgcgtccgacccgcctcgcgcgggccgtcgtggaggcctcggaggacttcgcg
aaactcatcgtcagcgaggagatgacctcgcaactcgaatccgacatgctggctatcgcc
cgcggcgaggccacgctggaggacgtcaccgaggagtccaaagagatgctcggagacgtg
ttcgagggcctcatggagtcccgcgaggaactcgggaaacagcttcaggactccctgaag
gccgacaagacggtcggcacctgtcccgactgtggcggcgacctcgtcgtccgcaagagc
cgccgtgggtcgtactttatcggctgtgactcctatcccgactgtacctacaccctcccg
ctcccctcgaccggcaagccgctcatcatggaggacgcctgcgaagagcacgacctccat
cacatcaagatgctcgccgggcgcaagacgttcgtccacggctgcccgctctgcaaggcc
gaggaagcggacgaagaagacgacctgattattgggtcgtgtcccgagtgcggtgagggt
gcgacgtcggaggcgtcgcaaggcgaaggcggtgaaaccgccgaagcgggcggcgaactc
gctatcaagcgcctccgttccggctcccgactcgtcggctgtacccgctatcccgactgc
gattactcgctgccgctcccccgccgcggcgacatcgaagtcacggacgaatcctgcgag
gaacacgacctgccggaactccgaatcacctacgagggcgaccgcgaaccgtgggacctc
ggctgtcccatctgtaactaccgcgagtatcaggcccagcagaacggcgagggcgggtcc
gacttagagagcatcaagggtatcggcgcaaagaccgccgagaaactgaaagacgccggt
atcgaggacgtgaagacgctgaaagcggccgagccggacgacgtggcttcgagagtggat
ggtgtcggtgcggatacggttcggaagtggcagactgcggctgactaa
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