Homo sapiens (human): 10905
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Entry
10905 CDS
T01001
Symbol
MAN1A2, MAN1B
Name
(RefSeq) mannosidase alpha class 1A member 2
KO
K01230
mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:
3.2.1.113
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00510
N-Glycan biosynthesis
hsa00513
Various types of N-glycan biosynthesis
hsa01100
Metabolic pathways
hsa04141
Protein processing in endoplasmic reticulum
Module
hsa_M00073
N-glycan precursor trimming
Network
nt06015
N-Glycan biosynthesis
Element
N00820
N-Glycan biosynthesis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00510 N-Glycan biosynthesis
10905 (MAN1A2)
00513 Various types of N-glycan biosynthesis
10905 (MAN1A2)
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
10905 (MAN1A2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
10905 (MAN1A2)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.113 mannosyl-oligosaccharide 1,2-alpha-mannosidase
10905 (MAN1A2)
Membrane trafficking [BR:
hsa04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
10905 (MAN1A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Glyco_hydro_47
iSTAND
Motif
Other DBs
NCBI-GeneID:
10905
NCBI-ProteinID:
NP_006690
OMIM:
604345
HGNC:
6822
Ensembl:
ENSG00000198162
UniProt:
O60476
LinkDB
All DBs
Position
1:117367449..117528872
Genome browser
AA seq
641 aa
AA seq
DB search
MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDS
SKHKRFDLGLEDVLIPHVDAGKGAKNPGVFLIHGPDEHRHREEEERLRNKIRADHEKALE
EAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK
REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLH
DEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIKAVQLAEKLLP
AFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVM
HIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEAR
KMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKA
GHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWY
LWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYL
YLLFSGDDLLPLDHWVFNTEAHPLPVLHLANTTLSGNPAVR
NT seq
1926 nt
NT seq
+upstream
nt +downstream
nt
atgactaccccagccctgctgcccctctctggacgtaggataccacctctgaacctgggg
ccgccttccttcccacatcacagggctaccttgagactttctgagaagtttattcttctc
cttattcttagtgccttcatcactctgtgttttggggcattctttttccttccagactct
tcaaaacacaaacgctttgatttgggtttagaagatgtgttaattccacatgtagatgcc
ggtaaaggggctaaaaaccccggagtcttcctgatccatggacccgatgaacatagacac
agggaagaggaagaacgtctgagaaataaaattcgagctgatcatgagaaggccttggaa
gaagcaaaagaaaaattaagaaagtcaagagaggaaattcgagcagaaattcagacagag
aaaaataaggtagtccaagaaatgaagataaaagagaacaagccactgccaccagtccct
attcccaaccttgtaggaatacgtggtggagacccagaagataatgacataagagagaaa
agggaaaaaattaaagagatgatgaaacatgcttgggataactataggacatatgggtgg
ggacataatgaactcagacctattgcaaggaaaggacactcccctaacatatttggaagt
tcacaaatgggtgctaccatagtagatgctttggataccctttatatcatgggacttcat
gatgaattcctagatgggcaaagatggattgaagacaaccttgatttcagtgtgaattca
gaggtgtctgtgtttgaagtcaacattcgatttattggaggcctacttgcagcatattac
ctatcaggagaggagatattcaagattaaagcagtgcaattggctgagaaactccttcct
gcctttaacacacctactgggattccttgggcaatggtgaatttgaaaagtggagtaggg
cgaaactggggctgggcatctgcaggtagcagcattctggctgaatttggtacactacat
atggagttcatccacctcagctacttgacaggggacctgacttactacaaaaaggttatg
cacattcggaaactacttcagaaaatggatcgtccaaatggtctttatccaaattatttg
aaccccagaacagggcgctggggtcagtatcatacatctgtcggtggcctgggagacagt
ttttatgaatacttactgaaagcatggttgatgtcagataaaacagaccatgaggcaaga
aagatgtatgatgatgctattgaggctatagaaaaacatcttattaagaagtctcgtgga
ggtcttacctttattggagaatggaagaatgggcacttggaaaaaaagatggggcatttg
gcctgctttgctgggggaatgtttgcactaggagcagatggttccagagcagataaagct
ggtcattatttagagctaggggcagaaattgcacgtacttgtcatgagtcatatgacaga
actgcattaaagctaggtcctgaatcattcaagtttgatggtgcagtggaggctgtggct
gtccggcaggctgaaaagtattatatcctccgtccagaagtaattgaaacctattggtac
ctatggcgattcactcacgatccaagatacaggcagtggggctgggaagcagcactggcc
attgaaaagtattgccgagttaatggtgggttttctggagtcaaagatgtatattcctct
actcctacacatgatgatgtacagcagagcttttttcttgctgaaacattaaaatatttg
tatctgctgttctccggtgatgaccttttacctttagaccactgggtgtttaatacagag
gctcaccctctgcctgtgttacatttagccaacaccacactttcaggtaatcctgctgtt
cgatga
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