Homo sapiens (human): 136 Entry 136               CDS       T01001                                  Gene name ADORA2B, ADORA2 Definition (RefSeq) adenosine A2b receptor   KO K04267   adenosine receptor A2b Organism hsa  Homo sapiens (human) Pathway hsa04015   Rap1 signaling pathway hsa04020   Calcium signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04270   Vascular smooth muscle contraction hsa05034   Alcoholism Drug target Adenosine (DG00243):  D00045 D02300 D02769 Caffeine (DG00974):  D00528 D01453 D07603 Enprofylline:  D04006 Brite KEGG Orthology (KO) [BR:hsa00001]  Environmental Information Processing   Signal transduction    04015 Rap1 signaling pathway     136 (ADORA2B)    04020 Calcium signaling pathway     136 (ADORA2B)   Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     136 (ADORA2B)  Organismal Systems   Circulatory system    04270 Vascular smooth muscle contraction     136 (ADORA2B)  Human Diseases   Substance dependence    05034 Alcoholism     136 (ADORA2B) G protein-coupled receptors [BR:hsa04030]  Class A. Rhodopsin family   Base and nucleoside    Adenosine     136 (ADORA2B) SSDB Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 GPR_Gpa2_C 7TM_GPCR_Sri 7TM_GPCR_Srx Other DBs NCBI-GeneID:  136 NCBI-ProteinID:  NP_000667 OMIM:  600446 HGNC:  264 HPRD:  15971 Ensembl:  ENSG00000170425 Vega:  OTTHUMG00000059140 Pharos:  P29275(Tclin) UniProt:  P29275 LinkDB Position 17p12 AA seq 332 aa MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT FHKIISRYLLCQADVKSGNGQAGVQPALGVGL NT seq 999 nt   +upstreamnt  +downstreamnt atgctgctggagacacaggacgcgctgtacgtggcgctggagctggtcatcgccgcgctt tcggtggcgggcaacgtgctggtgtgcgccgcggtgggcacggcgaacactctgcagacg cccaccaactacttcctggtgtccctggctgcggccgacgtggccgtggggctcttcgcc atcccctttgccatcaccatcagcctgggcttctgcactgacttctacggctgcctcttc ctcgcctgcttcgtgctggtgctcacgcagagctccatcttcagccttctggccgtggca gtcgacagatacctggccatctgtgtcccgctcaggtataaaagtttggtcacggggacc cgagcaagaggggtcattgctgtcctctgggtccttgcctttggcatcggattgactcca ttcctggggtggaacagtaaagacagtgccaccaacaactgcacagaaccctgggatgga accacgaatgaaagctgctgccttgtgaagtgtctctttgagaatgtggtccccatgagc tacatggtatatttcaatttctttgggtgtgttctgcccccactgcttataatgctggtg atctacattaagatcttcctggtggcctgcaggcagcttcagcgcactgagctgatggac cactcgaggaccaccctccagcgggagatccatgcagccaagtcactggccatgattgtg gggatttttgccctgtgctggttacctgtgcatgctgttaactgtgtcactcttttccag ccagctcagggtaaaaataagcccaagtgggcaatgaatatggccattcttctgtcacat gccaattcagttgtcaatcccattgtctatgcttaccggaaccgagacttccgctacact tttcacaaaattatctccaggtatcttctctgccaagcagatgtcaagagtgggaatggt caggctggggtacagcctgctctcggtgtgggcctatga

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