KEGG   Homo sapiens (human): 1543Help
Entry
1543              CDS       T01001                                 

Gene name
CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
Definition
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)
Orthology
K07408  
cytochrome P450, family 1, subfamily A, polypeptide 1 [EC:1.14.14.1]
Organism
hsa  Homo sapiens (human)
Pathway
Steroid hormone biosynthesis
Tryptophan metabolism
Retinol metabolism
Metabolism of xenobiotics by cytochrome P450
Metabolic pathways
Ovarian steroidogenesis
Chemical carcinogenesis
Class
Metabolism; Lipid metabolism; Steroid hormone biosynthesis [PATH:hsa00140]
Metabolism; Amino acid metabolism; Tryptophan metabolism [PATH:hsa00380]
Metabolism; Metabolism of cofactors and vitamins; Retinol metabolism [PATH:hsa00830]
Metabolism; Xenobiotics biodegradation and metabolism; Metabolism of xenobiotics by cytochrome P450 [PATH:hsa00980]
Organismal Systems; Endocrine system; Ovarian Steroidogenesis [PATH:hsa04913]
Human Diseases; Cancers; Chemical carcinogenesis [PATH:hsa05204]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
OMIM: 
HGNC: 
HPRD: 
Ensembl: 
Vega: 
UniProt: 
LinkDB All DBs
Structure
PDB: 

Jmol
Position
15q24.1
AA seq 512 aa AA seqDB search
MLFPISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGKNPH
LALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQS
MSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAG
PGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPIL
RYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANV
QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS
DRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKL
WVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEF
SVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS
NT seq 1539 nt NT seq  +upstreamnt  +downstreamnt
atgcttttcccaatctccatgtcggccacggagtttcttctggcctctgtcatcttctgt
ctggtattctgggtaatcagggcctcaagacctcaggtccccaaaggcctgaagaatcca
ccagggccatggggctggcctctgattgggcacatgctgaccctgggaaagaacccgcac
ctggcactgtcaaggatgagccagcagtatggggacgtgctgcagatccgaattggctcc
acacccgtggtggtgctgagcggcctggacaccatccggcaggccctggtgcggcagggc
gatgatttcaagggccggcccgacctctacaccttcaccctcatcagtaatggtcagagc
atgtccttcagcccagactctggaccagtgtgggctgcccgccggcgcctggcccagaat
ggcctgaaaagtttctccattgcctctgacccagcctcctcaacctcctgctacctggaa
gagcatgtgagcaaggaggctgaggtcctgataagcacgttgcaggagctgatggcaggg
cctgggcactttaacccctacaggtatgtggtggtatcagtgaccaatgtcatctgtgcc
atttgctttggccggcgctatgaccacaaccaccaagaactgcttagcctagtcaacctg
aataataatttcggggaggtggttggctctggaaacccagctgacttcatccctattctt
cgctacctacccaacccttccctgaatgccttcaaggacctgaatgagaagttctacagc
ttcatgcagaagatggtcaaggagcactacaaaacctttgagaagggccacatccgggac
atcacagacagcctgattgagcactgtcaggagaagcagctggatgagaacgccaatgtc
cagctgtcagatgagaagatcattaacatcgtcttggacctctttggagctgggtttgac
acagtcacaactgctatctcctggagcctcatgtatttggtgatgaaccccagggtacag
agaaagatccaagaggagctagacacagtgattggcaggtcacggcggccccggctctct
gacagatcccatctgccctatatggaggccttcatcctggagaccttccgacactcttcc
ttcgtccccttcaccatcccccacagcacaacaagagacacaagtttgaaaggcttttac
atccccaaggggcgttgtgtctttgtaaaccagtggcagatcaaccatgaccagaagcta
tgggtcaacccatctgagttcctacctgaacggtttctcacccctgatggtgctatcgac
aaggtgttaagtgagaaggtgattatctttggcatgggcaagcggaagtgtatcggtgag
accattgcccgctgggaggtctttctcttcctggctatcctgctgcaacgggtggaattc
agcgtgccactgggcgtgaaggtggacatgacccccatctatgggctaaccatgaagcat
gcctgctgtgagcacttccaaatgcagctgcgctcttag

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