| Entry |
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| Gene name |
PDE7B, bA472E5.1
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| Definition |
(RefSeq) phosphodiesterase 7B
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| KO |
| high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC: 3.1.4.53] |
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| Organism |
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| Pathway |
| Purine metabolism | | Morphine addiction |
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| Drug target |
Choline theophyllinate: Diprophylline: Propentofylline: Proxyphylline: Tibenelast sodium: Trapidil: |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
Metabolism
Nucleotide metabolism
00230 Purine metabolism
27115 (PDE7B)
Human Diseases
Substance dependence
05032 Morphine addiction
27115 (PDE7B)
Enzymes [BR:hsa01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
27115 (PDE7B)
 |
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GeneID: NCBI-ProteinID: OMIM: HGNC: HPRD: Ensembl: Vega: Pharos: UniProt: |
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| LinkDB |
 |
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| Position |
6q23.3
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| AA seq |
450 aa  
MSCLMVERCGEILFENPDQNAKCVCMLGDIRLRGQTGVRAERRGSYPFIDFRLLNSTTYS
GEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGMWDFDIF
LFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAAD
VTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMS
VLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHN
KDLRLEDAQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEIS
PLCNQQKDSIPSIQIGFMSYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLLPRQ
HRSRGSSGSGPDHDHAGQGTESEEQEGDSP |
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| NT seq |
1353 nt  +upstreamnt +downstreamnt
atgtcttgtttaatggttgagaggtgtggcgaaatcttgtttgagaaccccgatcagaat
gccaaatgtgtttgcatgctgggagatatacgactaaggggtcagacgggggttcgtgct
gaacgccgtggctcctacccattcattgacttccgcctacttaacagtacaacatactca
ggggagattggcaccaagaaaaaggtgaaaagactattaagctttcaaagatacttccat
gcatcaaggctgcttcgtggaattataccacaagcccctctgcacctgctggatgaagac
taccttggacaagcaaggcatatgctctccaaagtgggaatgtgggattttgacattttc
ttgtttgatcgcttgacaaatggaaacagcctggtaacactgttgtgccacctcttcaat
acccatggactcattcaccatttcaagttagatatggtgaccttacaccgatttttagtc
atggttcaagaagattaccacagccaaaacccgtatcacaatgctgttcacgcagccgac
gtcacccaggccatgcactgctacctgaaagagccaaagcttgccagcttcctcacgcct
ctggacatcatgcttggactgctggctgcagcagcacacgatgtggaccacccaggggtg
aaccagccatttttgataaaaactaaccaccatcttgcaaacctatatcagaatatgtct
gtgctggagaatcatcactggcgatctacaattggcatgcttcgagaatcaaggcttctt
gctcatttgccaaaggaaatgacacaggatattgaacagcagctgggctccttgatcttg
gcaacagacatcaacaggcagaatgaatttttgaccagattgaaagctcacctccacaat
aaagacttaagactggaggatgcacaggacaggcactttatgcttcagatcgccttgaag
tgtgctgacatttgcaatccttgtagaatctgggagatgagcaagcagtggagtgaaagg
gtctgtgaagaattctacaggcaaggtgaacttgaacagaaatttgaactggaaatcagt
cctctttgtaatcaacagaaagattccatccctagtatacaaattggtttcatgagctac
atcgtggagccgctcttccgggaatgggcccatttcacgggtaacagcaccctgtcggag
aacatgctgggccacctcgcacacaacaaggcccagtggaagagcctgttgcccaggcag
cacagaagcaggggcagcagtggcagcgggcctgaccacgaccacgcaggccaagggact
gagagcgaggagcaggaaggcgacagcccctag |
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