| Entry |
|
|---|
| Gene name |
HLA-DQB1, CELIAC1, HLA-DQB, IDDM1
|
|---|
| Definition |
(RefSeq) major histocompatibility complex, class II, DQ beta 1
|
|---|
| KO |
| major histocompatibility complex, class II |
|
|---|
| Organism |
|
|---|
| Pathway |
| Phagosome | | Cell adhesion molecules (CAMs) | | Antigen processing and presentation | | Hematopoietic cell lineage | | Th1 and Th2 cell differentiation | | Th17 cell differentiation | | Intestinal immune network for IgA production | | Type I diabetes mellitus | | Leishmaniasis | | Toxoplasmosis | | Staphylococcus aureus infection | | Tuberculosis | | Influenza A | | HTLV-I infection | | Herpes simplex infection | | Epstein-Barr virus infection | | Asthma | | Autoimmune thyroid disease | | Inflammatory bowel disease (IBD) | | Systemic lupus erythematosus | | Rheumatoid arthritis | | Allograft rejection | | Graft-versus-host disease | | Viral myocarditis |
|
|---|
| Disease |
| Asthma | | Systemic lupus erythematosus | | Hashimoto's thyroiditis | | Graves' disease | | Dilated cardiomyopathy (DCM) | | Viral myocarditis | | Tuberculosis | | Type I diabetes mellitus | | Dermatitis herpetiformis | | Multiple sclerosis | | Systemic sclerosis |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:hsa00001]
Environmental Information Processing
Signaling molecules and interaction
04514 Cell adhesion molecules (CAMs)
3119 (HLA-DQB1)
Cellular Processes
Transport and catabolism
04145 Phagosome
3119 (HLA-DQB1)
Organismal Systems
Immune system
04640 Hematopoietic cell lineage
3119 (HLA-DQB1)
04612 Antigen processing and presentation
3119 (HLA-DQB1)
04658 Th1 and Th2 cell differentiation
3119 (HLA-DQB1)
04659 Th17 cell differentiation
3119 (HLA-DQB1)
04672 Intestinal immune network for IgA production
3119 (HLA-DQB1)
Human Diseases
Immune diseases
05310 Asthma
3119 (HLA-DQB1)
05322 Systemic lupus erythematosus
3119 (HLA-DQB1)
05323 Rheumatoid arthritis
3119 (HLA-DQB1)
05320 Autoimmune thyroid disease
3119 (HLA-DQB1)
05321 Inflammatiory bowel disease (IBD)
3119 (HLA-DQB1)
05330 Allograft rejection
3119 (HLA-DQB1)
05332 Graft-versus-host disease
3119 (HLA-DQB1)
Cardiovascular diseases
05416 Viral myocarditis
3119 (HLA-DQB1)
Endocrine and metabolic diseases
04940 Type I diabetes mellitus
3119 (HLA-DQB1)
Infectious diseases
05150 Staphylococcus aureus infection
3119 (HLA-DQB1)
05152 Tuberculosis
3119 (HLA-DQB1)
05166 HTLV-I infection
3119 (HLA-DQB1)
05164 Influenza A
3119 (HLA-DQB1)
05168 Herpes simplex infection
3119 (HLA-DQB1)
05169 Epstein-Barr virus infection
3119 (HLA-DQB1)
05145 Toxoplasmosis
3119 (HLA-DQB1)
05140 Leishmaniasis
3119 (HLA-DQB1)
Exosome [BR:hsa04147]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
3119 (HLA-DQB1)
Exosomal proteins of epithelial cells
3119 (HLA-DQB1)
Exosomal proteins of breast milk
3119 (HLA-DQB1)
Cell adhesion molecules and their ligands [BR:hsa04516]
1. Immunoglobulin Superfamily
Immune system
Others
CD4; CD4 antigen [KO:K06454]
3119 (HLA-DQB1)
LAG3; lymphocyte-activation gene 3 protein [KO:K06565]
3119 (HLA-DQB1)
 |
|---|
| SSDB |
   |
|---|
| Motif |
 |
|---|
| Other DBs |
NCBI-GeneID: NCBI-ProteinID: OMIM: HGNC: Ensembl: Vega: Pharos: UniProt: |
|---|
| LinkDB |
 |
|---|
| Structure |
PDB: |
|---|
| Position |
6p21.32
|
|---|
| AA seq |
261 aa  
MSWKKALRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVS
RSIYNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELR
TTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLI
RNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVL
GLIFLGLGLIIHHRSQKGLLH |
|---|
| NT seq |
786 nt  +upstreamnt +downstreamnt
atgtcttggaaaaaggctttgcggatccccggaggccttcgggcagcaactgtgaccttg
atgctgtcgatgctgagcaccccagtggctgagggcagagactctcccgaggatttcgtg
taccagtttaagggcatgtgctacttcaccaacgggacagagcgcgtgcgtcttgtgagc
agaagcatctataaccgagaagagatcgtgcgcttcgacagcgacgtgggggagttccgg
gcggtgacgctgctggggctgcctgccgccgagtactggaacagccagaaggacatcctg
gagaggaaacgggcggcggtggacagggtgtgcagacacaactaccagttggagctccgc
acgaccttgcagcggcgagtggagcccacagtgaccatctccccatccaggacagaggcc
ctcaaccaccacaacctgctggtctgctcggtgacagatttctatccagcccagatcaaa
gtccggtggtttcggaatgaccaggaggagacagctggcgttgtgtccaccccccttatt
aggaatggtgactggaccttccagatcctggtgatgctggaaatgactccccagcgtgga
gacgtctacacctgccacgtggagcaccccagcctccagagccccatcaccgtggagtgg
cgggctcaatctgaatctgcccagagcaagatgctgagtggcattggaggcttcgtgctg
gggctgatcttcctcgggctgggccttatcatccatcacaggagtcagaaagggctcctg
cactga |
|---|
