Homo sapiens (human): 3274 Entry 3274              CDS       T01001                                  Gene name HRH2, H2R Definition (RefSeq) histamine receptor H2   KO K04150   histamine receptor H2 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04971   Gastric acid secretion Drug target Betazole:  D01187 Cimetidine (DG00017):  D00295 D03503 Dalcotidine:  D01698 Donetidine:  D03889 Etintidine hydrochloride:  D04098 Famotidine:  D00318 Histamine:  D08040 Icotidine:  D04494 Impromidine hydrochloride:  D04517 Lafutidine:  D01131 Lavoltidine succinate:  D04680 Lupitidine hydrochloride:  D04794 Metiamide:  D05004 Niperotidine:  D07072 Nizatidine:  D00440 Osutidine:  D01193 Oxmetidine (DG01225):  D05306 D05307 Pibutidine hydrochloride:  D01861 Ranitidine (DG00018):  D00422 D00673 Ranitidine bismuth citrate:  D05699 Roxatidine (DG00019):  D01467 D08494 D08495 Sufotidine:  D05939 Tiotidine:  D06157 Zaltidine hydrochloride:  D06355 Brite KEGG Orthology (KO) [BR:hsa00001]  Environmental Information Processing   Signal transduction    04020 Calcium signaling pathway     3274 (HRH2)   Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3274 (HRH2)  Organismal Systems   Digestive system    04971 Gastric acid secretion     3274 (HRH2) G protein-coupled receptors [BR:hsa04030]  Class A. Rhodopsin family   Biogenic amine [Fig]    Histamine [OT]     3274 (HRH2) SSDB Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 Other DBs NCBI-GeneID:  3274 NCBI-ProteinID:  NP_071640 OMIM:  142703 HGNC:  5183 HPRD:  00816 Ensembl:  ENSG00000113749 Vega:  OTTHUMG00000130660 Pharos:  P25021(Tclin) UniProt:  P25021 LinkDB Position 5q35.2 AA seq 359 aa MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR NT seq 1080 nt   +upstreamnt  +downstreamnt atggcacccaatggcacagcctcttccttttgcctggactctaccgcatgcaagatcacc atcaccgtggtccttgcggtcctcatcctcatcaccgttgctggcaatgtggtcgtctgt ctggccgtgggcttgaaccgccggctccgcaacctgaccaattgtttcatcgtgtccttg gctatcactgacctgctcctcggcctcctggtgctgcccttctctgccatctaccagctg tcctgcaagtggagctttggcaaggtcttctgcaatatctacaccagcctggatgtgatg ctctgcacagcctccattcttaacctcttcatgatcagcctcgaccggtactgcgctgtc atggacccactgcggtaccctgtgctggtcaccccagttcgggtcgccatctctctggtc ttaatttgggtcatctccattaccctgtcctttctgtctatccacctggggtggaacagc aggaacgagaccagcaagggcaatcataccacctctaagtgcaaagtccaggtcaatgaa gtgtacgggctggtggatgggctggtcaccttctacctcccgctactgatcatgtgcatc acctactaccgcatcttcaaggtcgcccgggatcaggccaagaggatcaatcacattagc tcctggaaggcagccaccatcagggagcacaaagccacagtgacactggccgccgtcatg ggggccttcatcatctgctggtttccctacttcaccgcgtttgtgtaccgtgggctgaga ggggatgatgccatcaatgaggtgttagaagccatcgttctgtggctgggctatgccaac tcagccctgaaccccatcctgtatgctgcgctgaacagagacttccgcaccgggtaccaa cagctcttctgctgcaggctggccaaccgcaactcccacaaaacttctctgaggtccaac gcctctcagctgtccaggacccaaagccgagaacccaggcaacaggaagagaaacccctg aagctccaggtgtggagtgggacagaagtcacggccccccagggagccacagacaggtaa

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