KEGG H.sapiens: 4312

Homo sapiens (human): 4312

Entry

4312 CDS H.sapiens

Gene name MMP1, CLG, CLGN

Definition matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7)

Orthology K01388 matrix metalloproteinase-1 (interstitial collagenase)
[EC:3.4.24.7]

Pathway hsa03320 PPAR signaling pathway
hsa05200 Pathways in cancer
hsa05219 Bladder cancer

Disease H00028 Choriocarcinoma

Class Organismal Systems; Endocrine System; PPAR signaling pathway
[PATH:hsa03320]
Human Diseases; Cancers; Pathways in cancer [PATH:hsa05200]
Human Diseases; Cancers; Bladder cancer [PATH:hsa05219]

SSDB

Motif Pfam: Peptidase_M10 Hemopexin PG_binding_1 Astacin Peptidase_M54
Peptidase_M66 Peptidase_M7 Peptidase_M57 Peptidase_M43
Metallopep
PROSITE: CYSTEINE_SWITCH HEMOPEXIN ZINC_PROTEASE

Other DBs NCBI-GI: 225543094
NCBI-GeneID: 4312
OMIM: 120353
HGNC: 7155
HPRD: 00384
Ensembl: ENSG00000196611
UniProt: B4DN15

Structure

PDB: 1HFC 966C 1CGE 1CGF 1SU3 2TCL 1CGL 2J0T
2CLT 3AYK 4AYK 1AYK 2AYK

Position 11q22.3

AA seq 403 aa
MQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLP
RADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQ
PGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDV
QLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDRFYMRTN
PFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYS
SFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKV
DAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN

NT seq 1212 nt +upstreamnt +downstreamnt
atgcaggaattctttgggctgaaagtgactgggaaaccagatgctgaaaccctgaaggtg
atgaagcagcccagatgtggagtgcctgatgtggctcagtttgtcctcactgaggggaac
cctcgctgggagcaaacacatctgacctacaggattgaaaattacacgccagatttgcca
agagcagatgtggaccatgccattgagaaagccttccaactctggagtaatgtcacacct
ctgacattcaccaaggtctctgagggtcaagcagacatcatgatatcttttgtcagggga
gatcatcgggacaactctccttttgatggacctggaggaaatcttgctcatgcttttcaa
ccaggcccaggtattggaggggatgctcattttgatgaagatgaaaggtggaccaacaat
ttcagagagtacaacttacatcgtgttgcagctcatgaactcggccattctcttggactc
tcccattctactgatatcggggctttgatgtaccctagctacaccttcagtggtgatgtt
cagctagctcaggatgacattgatggcatccaagccatatatggacgttcccaaaatcct
gtccagcccatcggcccacaaaccccaaaagcgtgtgacagtaagctaacctttgatgct
ataactacgattcggggagaagtgatgttctttaaagacagattctacatgcgcacaaat
cccttctacccggaagttgagctcaatttcatttctgttttctggccacaactgccaaat
gggcttgaagctgcttacgaatttgccgacagagatgaagtccggtttttcaaagggaat
aagtactgggctgttcagggacagaatgtgctacacggataccccaaggacatctacagc
tcctttggcttccctagaactgtgaagcatatcgatgctgctctttctgaggaaaacact
ggaaaaacctacttctttgttgctaacaaatactggaggtatgatgaatataaacgatct
atggatccaggttatcccaaaatgatagcacatgactttcctggaattggccacaaagtt
gatgcagttttcatgaaagatggatttttctatttctttcatggaacaagacaatacaaa
tttgatcctaaaacgaagagaattttgactctccagaaagctaatagctggttcaactgc
aggaaaaattga

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Disease (4)   
   KEGG DISEASE (1)   
   OMIM (3)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (2)   
   IPI (2)   
DNA sequence (14)   
   RefSeq(nuc) (2)   
   GenBank (6)   
   EMBL (6)   
3D Structure (13)   
   PDB (13)   
Protein domain (13)   
   Pfam (10)   
   PROSITE (3)   
All databases (66)

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