KEGG H.sapiens: 5467

Homo sapiens (human): 5467

Entry

5467 CDS H.sapiens

Gene name PPARD, FAAR, MGC3931, NR1C2, NUC1, NUCI, NUCII, PPARB

Definition peroxisome proliferator-activated receptor delta

Orthology K04504 peroxisome proliferator-activated receptor delta

Pathway hsa03320 PPAR signaling pathway
hsa04310 Wnt signaling pathway
hsa05200 Pathways in cancer
hsa05221 Acute myeloid leukemia

Class Environmental Information Processing; Signal Transduction; Wnt
signaling pathway [PATH:hsa04310]
Organismal Systems; Endocrine System; PPAR signaling pathway
[PATH:hsa03320]
Human Diseases; Cancers; Pathways in cancer [PATH:hsa05200]
Human Diseases; Cancers; Acute myeloid leukemia [PATH:hsa05221]

SSDB

Motif Pfam: zf-C4 Hormone_recep HsbA
PROSITE: NUCLEAR_REC_DBD_1 NUCLEAR_REC_DBD_2

Other DBs NCBI-GI: 284807155
NCBI-GeneID: 5467
OMIM: 600409
HGNC: 9235
HPRD: 02679
Ensembl: ENSG00000112033

Structure

PDB: 3GZ9 2B50 2AWH 3D5F 3ET2 2BAW 2GWX 3GWX
     1GWX 2ZNQ 1Y0S 2Q5G 3DY6 2ZNP 2ENV 2J14

Position 6p21.2-p21.1

AA seq 441 aa
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY

NT seq 1326 nt +upstreamnt +downstreamnt
atggagcagccacaggaggaagcccctgaggtccgggaagaggaggagaaagaggaagtg
gcagaggcagaaggagccccagagctcaatgggggaccacagcatgcacttccttccagc
agctacacagacctctcccggagctcctcgccaccctcactgctggaccaactgcagatg
ggctgtgacggggcctcatgcggcagcctcaacatggagtgccgggtgtgcggggacaag
gcatcgggcttccactacggtgttcatgcatgtgaggggtgcaagggcttcttccgtcgt
acgatccgcatgaagctggagtacgagaagtgtgagcgcagctgcaagattcagaagaag
aaccgcaacaagtgccagtactgccgcttccagaagtgcctggcactgggcatgtcacac
aacgctatccgttttggtcggatgccggaggctgagaagaggaagctggtggcagggctg
actgcaaacgaggggagccagtacaacccacaggtggccgacctgaaggccttctccaag
cacatctacaatgcctacctgaaaaacttcaacatgaccaaaaagaaggcccgcagcatc
ctcaccggcaaagccagccacacggcgccctttgtgatccacgacatcgagacattgtgg
caggcagagaaggggctggtgtggaagcagttggtgaatggcctgcctccctacaaggag
atcagcgtgcacgtcttctaccgctgccagtgcaccacagtggagaccgtgcgggagctc
actgagttcgccaagagcatccccagcttcagcagcctcttcctcaacgaccaggttacc
cttctcaagtatggcgtgcacgaggccatcttcgccatgctggcctctatcgtcaacaag
gacgggctgctggtagccaacggcagtggctttgtcacccgtgagttcctgcgcagcctc
cgcaaacccttcagtgatatcattgagcctaagtttgaatttgctgtcaagttcaacgcc
ctggaacttgatgacagtgacctggccctattcattgcggccatcattctgtgtggagac
cggccaggcctcatgaacgttccacgggtggaggctatccaggacaccatcctgcgtgcc
ctcgaattccacctgcaggccaaccaccctgatgcccagtacctcttccccaagctgctg
cagaagatggctgacctgcggcaactggtcaccgagcacgcccagatgatgcagcggatc
aagaagaccgaaaccgagacctcgctgcaccctctgctccaggagatctacaaggacatg
tactaa

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (9)   
   UniGene (1)   
   HGNC (1)   
   HPRD (1)   
   ENSEMBL-HSA (1)   
Protein sequence (9)   
   RefSeq(pep) (5)   
   IPI (4)   
DNA sequence (13)   
   RefSeq(nuc) (5)   
   GenBank (4)   
   EMBL (4)   
3D Structure (16)   
   PDB (16)   
Protein domain (5)   
   Pfam (3)   
   PROSITE (2)   
All databases (64)

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