| Entry |
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| Gene name |
SGSH, HSS, MPS3A, SFMD
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| Definition |
N-sulfoglucosamine sulfohydrolase (EC:3.10.1.1)
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| Orthology |
| N-sulfoglucosamine sulfohydrolase [EC: 3.10.1.1] |
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| Organism |
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| Pathway |
| Glycosaminoglycan degradation | | Metabolic pathways | | Lysosome |
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| Module |
| Heparan sulfate degradation |
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| Disease |
| Mucopolysaccharidosis type III (MPS3) | | Mucopolysaccharidosis (MPS) |
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| Class |
Metabolism; Glycan biosynthesis and metabolism; Glycosaminoglycan degradation [PATH: hsa00531]
Cellular Processes; Transport and catabolism; Lysosome [PATH: hsa04142]
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GI: NCBI-GeneID: OMIM: HGNC: HPRD: Ensembl: Vega: UniProt: |
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| LinkDB |
 |
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| Position |
17q25.3
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| AA seq |
502 aa  
MSCPVPACCALLLVLGLCRARPRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLF
RNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGI
IGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDP
HRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQY
TTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPE
HPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWAT
VFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQP
TGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWV
CAPDGVLEEKLSPQCQPLHNEL |
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| NT seq |
1509 nt  +upstreamnt +downstreamnt
atgagctgccccgtgcccgcctgctgcgcgctgctgctagtcctggggctctgccgggcg
cgtccccggaacgcactgctgctcctcgcggatgacggaggctttgagagtggcgcgtac
aacaacagcgccatcgccaccccgcacctggacgccttggcccgccgcagcctcctcttt
cgcaatgccttcacctcggtcagcagctgctctcccagccgcgccagcctcctcactggc
ctgccccagcatcagaatgggatgtacgggctgcaccaggacgtgcaccacttcaactcc
ttcgacaaggtgcggagcctgccgctgctgctcagccaagctggtgtgcgcacaggcatc
atcgggaagaagcacgtggggccggagaccgtgtacccgtttgactttgcgtacacggag
gagaatggctccgtcctccaggtggggcggaacatcactagaattaagctgctcgtccgg
aaattcctgcagactcaggatgaccggcctttcttcctctacgtcgccttccacgacccc
caccgctgtgggcactcccagccccagtacggaaccttctgtgagaagtttggcaacgga
gagagcggcatgggtcgtatcccagactggaccccccaggcctacgacccactggacgtg
ctggtgccttacttcgtccccaacaccccggcagcccgagccgacctggccgctcagtac
accaccgtcggccgcatggaccaaggagttggactggtgctccaggagctgcgtgacgcc
ggtgtcctgaacgacacactggtgatcttcacgtccgacaacgggatccccttccccagc
ggcaggaccaacctgtactggccgggcactgctgaacccttactggtgtcatccccggag
cacccaaaacgctggggccaagtcagcgaggcctacgtgagcctcctagacctcacgccc
accatcttggattggttctcgatcccgtaccccagctacgccatctttggctcgaagacc
atccacctcactggccggtccctcctgccggcgctggaggccgagcccctctgggccacc
gtctttggcagccagagccaccacgaggtcaccatgtcctaccccatgcgctccgtgcag
caccggcacttccgcctcgtgcacaacctcaacttcaagatgccctttcccatcgaccag
gacttctacgtctcacccaccttccaggacctcctgaaccgcaccacagctggtcagccc
acgggctggtacaaggacctccgtcattactactaccgggcgcgctgggagctctacgac
cggagccgggacccccacgagacccagaacctggccaccgacccgcgctttgctcagctt
ctggagatgcttcgggaccagctggccaagtggcagtgggagacccacgacccctgggtg
tgcgcccccgacggcgtcctggaggagaagctctctccccagtgccagcccctccacaat
gagctgtga |
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