Homo sapiens (human): 7066 Entry 7066              CDS       T01001                                  Gene name THPO, MGDF, MKCSF, ML, MPLLG, THCYT1, TPO Definition (RefSeq) thrombopoietin   KO K06854   thrombopoietin Organism hsa  Homo sapiens (human) Pathway hsa04060   Cytokine-cytokine receptor interaction hsa04630   Jak-STAT signaling pathway hsa04640   Hematopoietic cell lineage Brite KEGG Orthology (KO) [BR:hsa00001]  Environmental Information Processing   Signal transduction    04630 Jak-STAT signaling pathway     7066 (THPO)   Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     7066 (THPO)  Organismal Systems   Immune system    04640 Hematopoietic cell lineage     7066 (THPO) Cytokines [BR:hsa04052]  Class I cytokines (hematopoietin family)   Single chain family    7066 (THPO) SSDB Motif Pfam:  EPO_TPO Other DBs NCBI-GeneID:  7066 NCBI-ProteinID:  NP_000451 OMIM:  600044 HGNC:  11795 Ensembl:  ENSG00000090534 Vega:  OTTHUMG00000156745 Pharos:  P40225(Tbio) UniProt:  P40225 LinkDB Structure PDB:  1V7M 1V7N Position 3q27.1 AA seq 353 aa MELTELLLVVMLLLTARLTLSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPV LLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRL LLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTT AVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSGLLKWQQGFRAKIPGLLNQTSRSL DQIPGYLNRIHELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLPPNLQPGYSPSPTHPP TGQYTLFPLPPTLPTPVVQLHPLLPDPSAPTPTPTSPLLNTSYTHSQNLSQEG NT seq 1062 nt   +upstreamnt  +downstreamnt atggagctgactgaattgctcctcgtggtcatgcttctcctaactgcaaggctaacgctg tccagcccggctcctcctgcttgtgacctccgagtcctcagtaaactgcttcgtgactcc catgtccttcacagcagactgagccagtgcccagaggttcaccctttgcctacacctgtc ctgctgcctgctgtggactttagcttgggagaatggaaaacccagatggaggagaccaag gcacaggacattctgggagcagtgacccttctgctggagggagtgatggcagcacgggga caactgggacccacttgcctctcatccctcctggggcagctttctggacaggtccgtctc ctccttggggccctgcagagcctccttggaacccagcttcctccacagggcaggaccaca gctcacaaggatcccaatgccatcttcctgagcttccaacacctgctccgaggaaaggtg cgtttcctgatgcttgtaggagggtccaccctctgcgtcaggcgggccccacccaccaca gctgtccccagcagaacctctctagtcctcacactgaacgagctcccaaacaggacttct ggattgttggagacaaacttcactgcctcagccagaactactggctctgggcttctgaag tggcagcagggattcagagccaagattcctggtctgctgaaccaaacctccaggtccctg gaccaaatccccggatacctgaacaggatacacgaactcttgaatggaactcgtggactc tttcctggaccctcacgcaggaccctaggagccccggacatttcctcaggaacatcagac acaggctccctgccacccaacctccagcctggatattctccttccccaacccatcctcct actggacagtatacgctcttccctcttccacccaccttgcccacccctgtggtccagctc caccccctgcttcctgacccttctgctccaacgcccacccctaccagccctcttctaaac acatcctacacccactcccagaatctgtctcaggaagggtaa

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