KEGG T01001: 7879

Homo sapiens (human): 7879

Entry

7879 CDS T01001

Gene name

RAB7A, PRO2706, RAB7

Definition

RAB7A, member RAS oncogene family

Orthology

K07897

Ras-related protein Rab-7A

Organism

hsa Homo sapiens (human)

Pathway

hsa04144	Endocytosis
hsa04145	Phagosome
hsa05132	Salmonella infection
hsa05146	Amoebiasis
hsa05152	Tuberculosis

Disease

H00264	Charcot-Marie-Tooth disease (CMT)
H00265	Hereditary sensory and autonomic neuropathy (HSAN)

Brite

KEGG Orthology (KO) [BR:hsa00001]
Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    7879 (RAB7A)
   04145 Phagosome
    7879 (RAB7A)
Human Diseases
  Infectious diseases
   05132 Salmonella infection
    7879 (RAB7A)
   05152 Tuberculosis
    7879 (RAB7A)
   05146 Amoebiasis
    7879 (RAB7A)
Exosome [BR:hsa04147]
Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   7879 (RAB7A)
  Exosomal proteins of other body fluids (saliva and urine)
   7879 (RAB7A)
  Exosomal proteins of colorectal cancer cells
   7879 (RAB7A)
  Exosomal proteins of bladder cancer cells
   7879 (RAB7A)
GTP-binding proteins [BR:hsa04031]
Small (Monomeric) G-proteins
  Rab Family
   Rab7/9 [OT]
    7879 (RAB7A)

SSDB

Motif

Pfam:

Ras Miro Arf MMR_HSR1 Gtr1_RagA GTP_EFTU AAA_22 DUF258 Septin NTPase_1 PduV-EutP cobW ATP_bind_1 Arch_ATPase AAA_24 AAA_16 MobB AAA_5 SRPRB AAA_10 NACHT AAA_14

Other DBs

NCBI-GI:

NCBI-GeneID:

OMIM:

HGNC:

HPRD:

Ensembl:

Vega:

UniProt:

LinkDB

Structure

PDB:

1T91 3LAW 1YHN

Position

3q21.3

AA seq 207 aa
MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ
IWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPF
VVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEV
ELYNEFPEPIKLDKNDRAKASAESCSC

NT seq 624 nt +upstreamnt +downstreamnt
atgacctctaggaagaaagtgttgctgaaggttatcatcctgggagattctggagtcggg
aagacatcactcatgaaccagtatgtgaataagaaattcagcaatcagtacaaagccaca
ataggagctgactttctgaccaaggaggtgatggtggatgacaggctagtcacaatgcag
atatgggacacagcaggacaggaacggttccagtctctcggtgtggccttctacagaggt
gcagactgctgcgttctggtatttgatgtgactgcccccaacacattcaaaaccctagat
agctggagagatgagtttctcatccaggccagtccccgagatcctgaaaacttcccattt
gttgtgttgggaaacaagattgacctcgaaaacagacaagtggccacaaagcgggcacag
gcctggtgctacagcaaaaacaacattccctactttgagaccagtgccaaggaggccatc
aacgtggagcaggcgttccagacgattgcacggaatgcacttaagcaggaaacggaggtg
gagctgtacaacgaatttcctgaacctatcaaactggacaagaatgaccgggccaaggcc
tcggcagaaagctgcagttgctga

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