Homo sapiens (human): 8973
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Entry
8973 CDS
T01001
Symbol
CHRNA6, CHNRA6
Name
(RefSeq) cholinergic receptor nicotinic alpha 6 subunit
KO
K04808
nicotinic acetylcholine receptor alpha-6
Organism
hsa
Homo sapiens (human)
Pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04725
Cholinergic synapse
hsa05033
Nicotine addiction
Drug target
Acetylcholine (
DG01133
):
D00999
<JP/US>
Atracurium (
DG00771
):
D00758
<US>
Cisatracurium:
D00759
<US>
Cytisinicline:
D07770
Dimethyltubocurarine:
D07272
Doxacurium chloride:
D00760
Fazadinium bromide:
D07273
Hexamethonium bromide:
D02204
Lobeline (
DG01287
):
D02202
D02364
D08138
Mecamylamine (
DG00252
):
D00611
<US>
Mivacurium chloride:
D00763
Nicotine (
DG00994
):
D03365
<JP/US>
D05156
D05157
Pancuronium (
DG00769
):
D00492
Pipecuronium bromide:
D00764
Rocuronium bromide:
D00765
<JP/US>
Tubocurarine (
DG00767
):
D02207
D08655
Vecuronium (
DG00770
):
D00767
<US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
8973 (CHRNA6)
09150 Organismal Systems
09156 Nervous system
04725 Cholinergic synapse
8973 (CHRNA6)
09160 Human Diseases
09165 Substance dependence
05033 Nicotine addiction
8973 (CHRNA6)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
8973 (CHRNA6)
Ion channels [BR:
hsa04040
]
Ligand-gated channels
Acetylcholine (nicotinic)
8973 (CHRNA6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Neur_chan_LBD
Neur_chan_memb
DUF1286
Motif
Other DBs
NCBI-GeneID:
8973
NCBI-ProteinID:
NP_004189
OMIM:
606888
HGNC:
15963
Ensembl:
ENSG00000147434
UniProt:
Q15825
LinkDB
All DBs
Position
8:complement(42752620..42768786)
Genome browser
AA seq
494 aa
AA seq
DB search
MLTSKGQGFLHGGLCLWLCVFTPFFKGCVGCATEERLFHKLFSHYNQFIRPVENVSDPVT
VHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDI
VLYNNAVGDFQVEGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWT
YDKAEIDLLIIGSKVDMNDFWENSEWEIIDASGYKHDIKYNCCEEIYTDITYSFYIRRLP
MFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVV
PLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTTHTMPRWVKTVFLKLLPQVLLMRWPLD
KTRGTGSDAVPRGLARRPAKGKLASHGEPRHLKECFHCHKSNELATSKRRLSHQPLQWVV
ENSEHSPEVEDVINSVQFIAENMKSHNETKEVEDDWKYVAMVVDRVFLWVFIIVCVFGTA
GLFLQPLLGNTGKS
NT seq
1485 nt
NT seq
+upstream
nt +downstream
nt
atgctgaccagcaaggggcagggattccttcatgggggcttgtgtctctggctgtgtgtg
ttcacacctttctttaaaggctgtgtgggctgtgcaactgaggagaggctcttccacaaa
ctgttttctcattacaaccagttcatcaggcctgtggaaaacgtttccgaccctgtcacg
gtacactttgaagtggccatcacccagctggccaacgtggatgaagtaaaccagatcatg
gaaaccaatttgtggctgcgtcacatctggaatgattataaattgcgctgggatccaatg
gaatatgatggcattgagactcttcgcgttcctgcagataagatttggaagcccgacatt
gttctctataacaatgctgttggtgacttccaagtagaaggcaaaacaaaagctcttctt
aaatacaatggcatgataacctggactccaccagctatttttaagagttcctgccctatg
gatatcacctttttcccttttgatcatcaaaactgttccctaaaatttggttcctggacg
tatgacaaagctgaaattgatcttctaatcattggatcaaaagtggatatgaatgatttt
tgggaaaacagtgaatgggaaatcattgatgcctctggctacaaacatgacatcaaatac
aactgttgtgaagagatatacacagatataacctattctttctacattagaagattgccg
atgttttacacgattaatctgatcatcccttgtctctttatttcatttctaaccgtgttg
gtcttttaccttccttcggactgtggtgaaaaagtgacgctttgtatttcagtcctgctt
tctctgactgtgtttttgctggtcatcacagaaaccatcccatccacatctctggtggtc
ccactggtgggtgagtacctgctgttcaccatgatctttgtcacactgtccatcgtggtg
actgtgtttgtgttgaacatacactaccgcaccccaaccacgcacacaatgcccaggtgg
gtgaagacagttttcctgaagctgctgccccaggtcctgctgatgaggtggcctctggac
aagacaaggggcacaggctctgatgcagtgcccagaggccttgccaggaggcctgccaaa
ggcaagcttgcaagccatggggaacccagacatcttaaagaatgcttccattgtcacaaa
tcaaatgagcttgccacaagcaagagaagattaagtcatcagccattacagtgggtggtg
gaaaattcggagcactcgcctgaagttgaagatgtgattaacagtgttcagttcatagca
gaaaacatgaagagccacaatgaaaccaaggaggtagaagatgactggaaatacgtggcc
atggtggtggacagagtatttctttgggtatttataattgtctgtgtatttggaactgca
gggctatttctacagccactacttgggaacacaggaaaatcttaa
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