KEGG ORTHOLOGY: K00693

ORTHOLOGY: K00693

Entry

K00693 KO

Name

GYS

Definition

glycogen synthase [EC:2.4.1.11]

Pathway

ko00500	Starch and sucrose metabolism
ko01100	Metabolic pathways
ko04151	PI3K-Akt signaling pathway
ko04152	AMPK signaling pathway
ko04910	Insulin signaling pathway
ko04922	Glucagon signaling pathway
ko04931	Insulin resistance

Disease

H00069	Glycogen storage diseases (GSD)
H01760	Hepatic glycogen storage disease
H01762	Muscle glycogen storage disease
H01949	Glycogen storage disease type 0b
H01950	Glycogen storage disease type 0a

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Carbohydrate metabolism
   00500 Starch and sucrose metabolism
    K00693  GYS; glycogen synthase
Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K00693  GYS; glycogen synthase
   04152 AMPK signaling pathway
    K00693  GYS; glycogen synthase
Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    K00693  GYS; glycogen synthase
   04922 Glucagon signaling pathway
    K00693  GYS; glycogen synthase
Human Diseases
  Endocrine and metabolic diseases
   04931 Insulin resistance
    K00693  GYS; glycogen synthase
Enzymes [BR:ko01000]
2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.11  glycogen(starch) synthase
     K00693  GYS; glycogen synthase
Glycosyltransferases [BR:ko01003]
Polysaccharide
  Storage polysaccharide
   K00693  GYS; glycogen synthase

Other DBs

RN:

COG:

GO:

CAZy:

Genes

HSA:	2997(GYS1) 2998(GYS2)
PTR:	456196(GYS1) 465336(GYS2)
PPS:	100972797(GYS2) 100990031(GYS1)
GGO:	101131537(GYS2) 101132203(GYS1)
PON:	100172871(GYS1) 100452879(GYS2)
NLE:	100579728(GYS1) 101177222(GYS2)
MCC:	574233(GYS1) 706152(GYS2)
MCF:	102134439(GYS1) 102145637(GYS2)
CSAB:	103218736(GYS2) 103235009(GYS1)
RRO:	104660892(GYS2) 104666538(GYS1)
RBB:	108523620(GYS1) 108539726(GYS2)
CJC:	100406574(GYS1)
SBQ:	101040983(GYS2) 101050509(GYS1)
MMU:	14936(Gys1) 232493(Gys2)
RNO:	25623(Gys2) 690987(Gys1)
CGE:	100769788(Gys1) 100770628(Gys2)
NGI:	103743640(Gys1) 103748807(Gys2)
HGL:	101699800(Gys2) 101712358(Gys1)
CCAN:	109682689 109682693 109682705(Gys1) 109684212(Gys2)
OCU:	100008660(GYS1) 100352840(GYS2)
TUP:	102469649(GYS1) 102472146(GYS2)
CFA:	403737(GYS2) 611993(GYS1)
AML:	100470220(GYS2) 100476206(GYS1)
UMR:	103657110(GYS1) 103665227(GYS2)
ORO:	101368722(GYS2) 101370584(GYS1)
FCA:	101092123(GYS2) 101100682(GYS1)
PTG:	102950123(GYS1) 102965400(GYS2)
AJU:	106967981(GYS2) 106988702(GYS1)
BTA:	511047(GYS1) 537451(GYS2) 786335(GYS1)
BOM:	102272943(GYS2) 102278988(GYS1)
BIU:	109559597(GYS2) 109571966 109572216(GYS1)
PHD:	102324800(GYS1) 102332125(GYS2)
CHX:	102188970(GYS1) 102189015(GYS2)
OAS:	101108772(GYS1) 101118685(GYS2)
SSC:	100157080(GYS2) 574064(GYS1)
CFR:	102511249(GYS1) 102511313(GYS2)
CDK:	105096485(GYS2) 105102888(GYS1)
BACU:	103007749(GYS2) 103019791(GYS1)
LVE:	103074944(GYS2) 103084996(GYS1)
OOR:	101284496(GYS1) 101287552(GYS2)
ECB:	100054723(GYS1) 100064264(GYS2)
EPZ:	103553309(GYS1) 103554933(GYS2)
EAI:	106825573(GYS2) 106838266(GYS1)
MYB:	102251419(GYS2) 102262755(GYS1)
MYD:	102771674(GYS2) 102775147(GYS1)
HAI:	109375142(GYS2) 109390996(GYS1)
RSS:	109450635(GYS2) 109452589(GYS1)
PALE:	102884634(GYS1) 102890809(GYS2)
LAV:	100658178(GYS2) 100659799(GYS1)
TMU:	101355539 101357774
MDO:	100010618(GYS2) 100030435(GYS1)
SHR:	100918400(GYS2) 100920298(GYS1)
OAA:	100074446(GYS1)
GGA:	418201(GYS2)
MGP:	100547308(GYS2)
CJO:	107316995(GYS2)
APLA:	101795011(GYS2)
ACYG:	106038297(GYS2)
TGU:	100232653(GYS2)
GFR:	102038432(GYS2)
FAB:	101821843(GYS2)
PHI:	102105522(GYS2) 102106773(GYS1)
PMAJ:	107205059(GYS2)
CCW:	104696143(GYS2)
FPG:	101918224(GYS2) 106112713(GYS1)
FCH:	102051571(GYS2)
CLV:	102095088(GYS2)
EGZ:	104135134(GYS2)
AAM:	106486701 106488410(GYS2)
ASN:	102372928(GYS1) 102375223(GYS2)
AMJ:	102573726(GYS1) 106737074(GYS2)
PSS:	102449457(GYS2) 102462946(GYS1)
CMY:	102943466(GYS1) 102944417(GYS2)
CPIC:	101939182(GYS2) 101947252(GYS1)
ACS:	100555409(gys2) 100563034(gys1)
PVT:	110078508(GYS1) 110083005(GYS2)
PBI:	103048016(GYS1) 103058373(GYS2)
GJA:	107116591(GYS1) 107122425
XLA:	108696758 108697802 431912(gys2.L)
XTR:	100490155(gys1) 548515(gys2)
NPR:	108789874 108798558(GYS2) 108801187 108802164
DRE:	373082(gys2) 394155(gys1)
SRX:	107725632(gys2) 107731036 107754987
SANH:	107653402 107659841 107690304 107694689
SGH:	107560743 107560754 107567534(gys1) 107580651 107590896(gys2) 107592972
CCAR:	109069551 109071391 109074896(gys2) 109113598
IPU:	108256446(gys1) 108279630(gys2)
AMEX:	103022388 103040242(gys2)
TRU:	101077099(gys1) 101079536(gys2)
TNG:	GSTEN00013911G001 GSTEN00021890G001 GSTEN00021891G001
LCO:	104927634(gys2) 104930340(gys1) 109142472
NCC:	104942714(gys1) 104960946 104961097
MZE:	101474059(gys2) 101485531(gys1)
OLA:	101155437(gys1) 101163866(gys2)
XMA:	102217274 102233516(gys1)
PRET:	103459579(gys2) 103469092(gys1)
NFU:	107376658 107381436(gys2)
CSEM:	103383026(gys2) 103392977
LCF:	108881009(gys1) 108897478 108899721
HCQ:	109514852(gys1) 109520116(gys2)
BPEC:	110158208(gys1) 110162197 110172488(gys2)
SASA:	106566433 106601949 106601986 106606415(gys1)
ELS:	105007707 105020183(gys2)
SFM:	108923853 108931365(gys2) 108941810
LCM:	102359961(GYS2) 102360620(GYS1)
CMK:	103174867 103181070(gys2) 103190159
BFO:	BRAFLDRAFT_119087
CIN:	100183713
SPU:	578305
APLC:	110975475
SKO:	100368259
DME:	Dmel_CG6904(GlyS)
DPO:	Dpse_GA19945
DAN:	Dana_GF17161
DER:	Dere_GG20891
DPE:	Dper_GL21689
DSE:	Dsec_GM25805
DSI:	Dsimw501_GD20381(Dsim_GD20381)
DWI:	Dwil_GK13980
DYA:	Dyak_GE26410
DGR:	Dgri_GH14560
DMO:	Dmoj_GI23664
DVI:	Dvir_GJ23225
MDE:	101890004
AGA:	AgaP_AGAP002586
AAG:	5564353
CQU:	CpipJ_CPIJ005086
AME:	552328
BIM:	100748309
BTER:	100647195
SOC:	105206087
AEC:	105155041
ACEP:	105620164
PBAR:	105432338
HST:	105182643
CFO:	105249547
LHU:	105669367
PGC:	109860044
NVI:	100119226
TCA:	662050
DPA:	109542106
NVL:	108564856
BMOR:	101736417
DPL:	KGM_214402
PMAC:	106716340
PRAP:	110996075
PXY:	105383166 105398308
API:	100166026
DNX:	107164888 107170933
PHU:	Phum_PHUM235980
ZNE:	110833071
FCD:	110845614
DPX:	DAPPUDRAFT_307387(GYS) DAPPUDRAFT_314896
ISC:	IscW_ISCW006570
TUT:	107372104
CEL:	CELE_Y46G5A.31(gsy-1)
CBR:	CBG18401(Cbr-gsy-1)
NAI:	NECAME_00166 NECAME_00168 NECAME_14536
BMY:	Bm1_50190 Bm1_53420
LOA:	LOAG_15238 LOAG_15409 LOAG_15760 LOAG_16100 LOAG_18542
TSP:	Tsp_00121
HRO:	HELRODRAFT_157348 HELRODRAFT_64031
LGI:	LOTGIDRAFT_206655
CRG:	105341160
MYI:	110453713
OBI:	106882342
LAK:	106168839
SMM:	Smp_018260
SHX:	MS3_08291
OVI:	T265_08924
NVE:	NEMVE_v1g164483
EPA:	110233733
HMG:	100197472(gys1)
TAD:	TRIADDRAFT_20144
AQU:	100640802
SCE:	YFR015C(GSY1) YLR258W(GSY2)
AGO:	AGOS_AAR008W
ERC:	Ecym_1276
KLA:	KLLA0F23133g
KMX:	KLMA_30370(GSY2)
LTH:	KLTH0H11418g
VPO:	Kpol_1069p14 Kpol_295p5
ZRO:	ZYRO0E05566g
CGR:	CAGL0F04719g CAGL0K10626g
NCS:	NCAS_0A08870(NCAS0A08870) NCAS_0D00640(NCAS0D00640)
NDI:	NDAI_0G05290(NDAI0G05290) NDAI_0H03510(NDAI0H03510)
TPF:	TPHA_0B03550(TPHA0B03550) TPHA_0O01130(TPHA0O01130)
TBL:	TBLA_0D05020(TBLA0D05020)
TDL:	TDEL_0B06310(TDEL0B06310)
KAF:	KAFR_0C04470(KAFR0C04470) KAFR_0I02020(KAFR0I02020)
PPA:	PAS_chr3_0781
DHA:	DEHA2B05896g
PIC:	PICST_81231(GSY1)
PGU:	PGUG_00799
SPAA:	SPAPADRAFT_59970
LEL:	LELG_00490
CAL:	CAALFM_CR00780CA(GSY1)
CTP:	CTRG_01001
COT:	CORT_0A05610
CDU:	CD36_25850
CTEN:	CANTEDRAFT_131596
YLI:	YALI0F18502g
CLU:	CLUG_03653
CLUS:	A9F13_01g05082
CAUR:	QG37_03063
SLB:	AWJ20_4133(GSY1)
NCR:	NCU06687(gsy-1)
NTE:	NEUTE1DRAFT57176(NEUTE1DRAFT_57176)
SMP:	SMAC_06646
PAN:	PODANSg8987
TTT:	THITE_2107582
MTM:	MYCTH_2301334
CTHR:	CTHT_0028430
MGR:	MGG_07289
TMN:	UCRPA7_5828
FGR:	FGSG_06822
FPU:	FPSE_11843
FVR:	FVEG_05164
FOX:	FOXG_02003
NHE:	NECHADRAFT_71857
TRE:	TRIREDRAFT_44529(gys1)
MAW:	MAC_05928
MAJ:	MAA_07866
CMT:	CCM_03736
PLJ:	VFPFJ_07956
VAL:	VDBG_04164
VDA:	VDAG_01389
CFJ:	CFIO01_08925
ELA:	UCREL1_3245
PFY:	PFICI_10952
SSL:	SS1G_07818
BFU:	BC1G_11987
MBE:	MBM_08435
PSCO:	LY89DRAFT_684369
GLZ:	GLAREA_11708
ANI:	AN8010.2
AFM:	AFUA_5G02480
AOR:	AO090102000361
ANG:	ANI_1_1448024(An02g10310)
AFV:	AFLA_004660
ACT:	ACLA_002680
NFI:	NFIA_039600
PCS:	Pc21g15690
PDP:	PDIP_48670
CIM:	CIMG_06454
CPW:	CPC735_029470
PBL:	PAAG_07276
PBN:	PADG_05778
URE:	UREG_03962
ABE:	ARB_06804
TVE:	TRV_06758
AJE:	HCAG_00415
PNO:	SNOG_15514
PTE:	PTT_15101
BZE:	COCCADRAFT_86955
BSC:	COCSADRAFT_111021
BOR:	COCMIDRAFT_93452
AALT:	CC77DRAFT_1092893
ZTR:	MYCGRDRAFT_74660
PFJ:	MYCFIDRAFT_211585
BCOM:	BAUCODRAFT_36702
NPA:	UCRNP2_6446
TML:	GSTUM_00003828001
CNE:	CNJ00590
CNB:	CNBJ2910
CGI:	CGB_D9190C
TMS:	TREMEDRAFT_37716
TVS:	TRAVEDRAFT_155607 TRAVEDRAFT_33770
DSQ:	DICSQDRAFT_68795
PCO:	PHACADRAFT_187812
SHS:	STEHIDRAFT_104983
HIR:	HETIRDRAFT_65834
PSQ:	PUNSTDRAFT_55501
ADL:	AURDEDRAFT_92025
FME:	FOMMEDRAFT_112192 FOMMEDRAFT_159404 FOMMEDRAFT_170015
GTR:	GLOTRDRAFT_63876
LBC:	LACBIDRAFT_189159
MPR:	MPER_16264
MRR:	Moror_15309
CCI:	CC1G_01973
SCM:	SCHCODRAFT_76992
ABP:	AGABI1DRAFT77702(AGABI1DRAFT_77702)
ABV:	AGABI2DRAFT212415(AGABI2DRAFT_212415)
CPUT:	CONPUDRAFT_61355
SLA:	SERLADRAFT_450768
UMA:	UMAG_01009
PFP:	PFL1_01019
PGR:	PGTG_07651 PGTG_20898 PGTG_20899
MLR:	MELLADRAFT_50486
MBR:	MONBRDRAFT_39385
SRE:	PTSG_03493
DDI:	DDB_G0267674(glcS)
DPP:	DICPUDRAFT_148003
DFA:	DFA_00663(glcS)
ACAN:	ACA1_326120
GLA:	GL50803_104031
PHM:	PSMK_02050
SFC:	Spiaf_0522
SCN:	Solca_1153
CHU:	CHU_1581(glgA)
DFE:	Dfer_3735
SLI:	Slin_5697
SRD:	SD10_25640
SMON:	AWR27_22520
SPIR:	CWM47_15435
LBY:	Lbys_2865
RSI:	Runsl_2125
EOL:	Emtol_1603
FAE:	FAES_1227
FIB:	A6C57_13395
HSW:	Hsw_2975
HYM:	N008_14405
HYE:	AM218_03435
HYG:	AUC43_11575
HYP:	A0257_07515
HYZ:	AXW84_14750
RUF:	TH63_09035
RTI:	DC20_20720
RUD:	TH61_16600
MTT:	Ftrac_3576
FLM:	MY04_1504(glgA)
NAA:	Nps_00385
NAC:	AQV86_01510

» show all

Reference

PMID:22248338

Authors

Roach PJ, Depaoli-Roach AA, Hurley TD, Tagliabracci VS

Title

Glycogen and its metabolism: some new developments and old themes.

Journal

Biochem J 441:763-87 (2012)
DOI:10.1042/BJ20111416

LinkDB

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