KEGG ORTHOLOGY: K04166

ORTHOLOGY: K04166

Entry

K04166                      KO

Symbol

AGTR1

Name

angiotensin II receptor type 1

Pathway

map04020

Calcium signaling pathway

map04022

cGMP-PKG signaling pathway

map04072

Phospholipase D signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04261

Adrenergic signaling in cardiomyocytes

map04270

Vascular smooth muscle contraction

map04371

Apelin signaling pathway

map04614

Renin-angiotensin system

map04924

Renin secretion

map04925

Aldosterone synthesis and secretion

map04927

Cortisol synthesis and secretion

map04933

AGE-RAGE signaling pathway in diabetic complications

map04934

Cushing syndrome

map05171

Coronavirus disease - COVID-19

map05200

Pathways in cancer

map05415

Diabetic cardiomyopathy

Disease

H00575

Renal tubular dysgenesis

H01633

High blood pressure

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K04166  AGTR1; angiotensin II receptor type 1
   04020 Calcium signaling pathway
    K04166  AGTR1; angiotensin II receptor type 1
   04072 Phospholipase D signaling pathway
    K04166  AGTR1; angiotensin II receptor type 1
   04022 cGMP-PKG signaling pathway
    K04166  AGTR1; angiotensin II receptor type 1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04166  AGTR1; angiotensin II receptor type 1
09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    K04166  AGTR1; angiotensin II receptor type 1
   04614 Renin-angiotensin system
    K04166  AGTR1; angiotensin II receptor type 1
   04925 Aldosterone synthesis and secretion
    K04166  AGTR1; angiotensin II receptor type 1
   04927 Cortisol synthesis and secretion
    K04166  AGTR1; angiotensin II receptor type 1
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04166  AGTR1; angiotensin II receptor type 1
   04270 Vascular smooth muscle contraction
    K04166  AGTR1; angiotensin II receptor type 1
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04166  AGTR1; angiotensin II receptor type 1
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K04166  AGTR1; angiotensin II receptor type 1
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K04166  AGTR1; angiotensin II receptor type 1
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04166  AGTR1; angiotensin II receptor type 1
   04934 Cushing syndrome
    K04166  AGTR1; angiotensin II receptor type 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K04166  AGTR1; angiotensin II receptor type 1
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04166  AGTR1; angiotensin II receptor type 1
Membrane trafficking [BR:ko04131]
Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    K04166  AGTR1; angiotensin II receptor type 1
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Peptide
   Angiotensin
    K04166  AGTR1; angiotensin II receptor type 1

Other DBs

GO:

0001596

TC:	9.A.14.13.1

Genes

HSA:	185(AGTR1)

PTR:	460762(AGTR1)

PPS:	100992718(AGTR1)

GGO:	101128433(AGTR1)

PON:	100461588(AGTR1)

NLE:	100603931(AGTR1)

HMH:	116480239(AGTR1)

MCC:	712773(AGTR1)

MCF:	102130940(AGTR1)

MTHB:

126947490

MNI:	105470040(AGTR1)

CSAB:

103241511(AGTR1)

CATY:

105587504(AGTR1)

PANU:

101003219(AGTR1)

TGE:	112618692(AGTR1)

MLEU:

105534119(AGTR1)

RRO:	104671550(AGTR1)

RBB:	108518305(AGTR1)

TFN:	117084057(AGTR1)

PTEH:

111544725(AGTR1)

CANG:

105523879(AGTR1)

CJC:	100406419(AGTR1)

SBQ:	101037991(AGTR1)

CIMI:

108300862(AGTR1)

CSYR:

103275580(AGTR1)

MMUR:

105881238(AGTR1)

LCAT:

123630151(AGTR1)

PCOQ:

105809190(AGTR1)

OGA:	100954924(AGTR1)

MMU:	11607(Agtr1a) 11608(Agtr1b)

MCAL:

110291663(Agtr1) 110307911

MPAH:

110320654(Agtr1) 110333989

RNO:	24180(Agtr1a) 81638(Agtr1b)

MCOC:

116082258 116094994(Agtr1)

ANU:	117707297(Agtr1) 117713323

MUN:	110539373 110563019(Agtr1)

CGE:	100750798(Agtr1) 100755233

MAUA:

101834569(Agtr1) 101840244

PROB:

127223377(Agtr1) 127229374

PLEU:

114686251(Agtr1) 114701075

MORG:

121433907 121452947(Agtr1)

MFOT:

126490666 126501581

AAMP:

119817416 119826658(Agtr1)

NGI:	103737006 103745994(Agtr1)

HGL:	101714068(Agtr1)

CPOC:

100192325(Agtr1)

CCAN:

109682820(Agtr1)

DORD:

105996000(Agtr1)

DSP:	122095227(Agtr1)

PLOP:

125342450(Agtr1)

NCAR:

124992863

MMMA:

107143327(Agtr1)

OCU:	100009164(AGTR1)

OPI:	101531941(AGTR1)

TUP:	102469571(AGTR1)

GVR:	103597449(AGTR1)

CFA:	403836(AGTR1)

CLUD:

112661078(AGTR1)

VVP:	112932806(AGTR1)

VLG:	121478784(AGTR1)

NPO:	129507359(AGTR1)

AML:	100471220(AGTR1)

UMR:	103678133(AGTR1)

UAH:	113254038(AGTR1)

UAR:	123802390(AGTR1)

ELK:

111150851

LLV:

125098485

MPUF:

101685981(AGTR1)

MNP:	132012148(AGTR1)

MLK:	131825026(AGTR1)

NVS:	122910442(AGTR1)

ORO:	101377034(AGTR1)

EJU:	114209124(AGTR1)

ZCA:	113915804(AGTR1)

MLX:	118004937(AGTR1)

NSU:	110576788(AGTR1)

LWW:	102733129(AGTR1)

FCA:	101082936(AGTR1)

PYU:	121033803(AGTR1)

PCOO:

112849615(AGTR1)

PBG:	122491879(AGTR1)

PVIV:

125175752(AGTR1)

LRUF:

124526985

PTG:	102968872(AGTR1)

PPAD:

109260696(AGTR1)

PUC:

125921942

AJU:

106975222

HHV:	120237605(AGTR1)

BTA:	281607(AGTR1)

BOM:	102264884(AGTR1)

BIU:	109559421(AGTR1)

BBUB:

102406935(AGTR1)

BBIS:

105001755(AGTR1)

CHX:	102174163(AGTR1)

OAS:	443107(AGTR1)

BTAX:

128048751(AGTR1)

ODA:	120858385(AGTR1)

CCAD:

122445077(AGTR1)

MBEZ:

129546793(AGTR1)

SSC:	100519976(AGTR1)

CBAI:

105081270(AGTR1)

CDK:	105089509(AGTR1)

VPC:	102531032(AGTR1)

BACU:

103001868(AGTR1)

BMUS:

118894942(AGTR1)

LVE:	103090648(AGTR1)

OOR:	101269573(AGTR1)

DLE:	111179290(AGTR1)

PCAD:

102980831(AGTR1)

PSIU:

116753672(AGTR1)

NASI:

112415934(AGTR1)

ECB:	100059005(AGTR1)

EPZ:	103558752(AGTR1)

EAI:	106829436(AGTR1)

MYB:	102245101(AGTR1)

MYD:	102772519(AGTR1)

MMYO:

118677044(AGTR1)

MLF:	102418550(AGTR1)

PKL:	118722865(AGTR1)

EFUS:

103302014(AGTR1)

MNA:	107544042(AGTR1)

DRO:	112301009(AGTR1)

SHON:

118997940(AGTR1)

AJM:	119055972(AGTR1)

PDIC:

114490804(AGTR1)

PHAS:

123827516(AGTR1)

MMF:	118617533(AGTR1)

PPAM:

129079912(AGTR1)

HAI:	109375864(AGTR1)

RFQ:	117013699(AGTR1)

PALE:

102895602(AGTR1)

PGIG:

120593730(AGTR1)

PVP:	105294948(AGTR1)

RAY:	107513418(AGTR1)

MJV:	108388618(AGTR1)

TOD:	119256911(AGTR1)

SARA:

101537266(AGTR1)

SETR:

126025545(AGTR1)

LAV:	100659079(AGTR1)

TMU:

101346145

ETF:	101646805(AGTR1)

DNM:	101437710(AGTR1)

MDO:	100017858(AGTR1)

GAS:	123240202(AGTR1) 123254602

SHR:	100927259(AGTR1)

AFZ:

127552968

PCW:	110204798(AGTR1)

OAA:	100077014(AGTR1)

GGA:	396065(AGTR1)

PCOC:

116230872(AGTR1)

MGP:	100303701(AGTR1)

CJO:	107318295(AGTR1)

TPAI:

128082574(AGTR1)

LMUT:

125697883(AGTR1)

NMEL:

110398297(AGTR1)

APLA:

101804939(AGTR1)

ACYG:

106036265(AGTR1)

CATA:

118247061(AGTR1)

AFUL:

116492551(AGTR1)

TGU:	100224975(AGTR1)

LSR:	110473886(AGTR1)

SCAN:

103815406(AGTR1)

PMOA:

120508585(AGTR1)

OTC:	121341132(AGTR1)

PRUF:

121357959(AGTR1)

GFR:	102033965(AGTR1)

FAB:	101812375(AGTR1)

OMA:	130256987(AGTR1)

PHI:	102112440(AGTR1)

PMAJ:

107209000(AGTR1)

CCAE:

111933486(AGTR1)

CCW:	104693469(AGTR1)

CBRC:

103624821(AGTR1)

ETL:	114057376(AGTR1)

ZAB:	102070127(AGTR1)

ACHL:

103811509(AGTR1)

SVG:	106862581(AGTR1)

MMEA:

130580393(AGTR1)

HRT:	120757435(AGTR1)

FPG:	101914397(AGTR1)

FCH:	102052791(AGTR1)

CLV:	102098897(AGTR1)

EGZ:	104127122(AGTR1)

NNI:	104015689(AGTR1)

PCRI:

104026496(AGTR1)

PLET:

104622670(AGTR1)

EHS:	104514126(AGTR1)

PCAO:

104048285(AGTR1)

ACUN:

113483374(AGTR1)

TALA:

104359306(AGTR1)

PADL:

103913836(AGTR1)

AFOR:

103901439(AGTR1)

ACHC:

115347609(AGTR1)

HALD:

104314089(AGTR1)

HLE:	104832260(AGTR1)

AGEN:

126039603

GCL:

127020224

CCRI:

104161254(AGTR1)

CSTI:

104552644(AGTR1)

CMAC:

104476158(AGTR1)

MUI:	104535605(AGTR1)

BREG:

104631598(AGTR1)

FGA:	104082616(AGTR1)

GSTE:

104265087(AGTR1)

LDI:	104352695(AGTR1)

MNB:	103771137(AGTR1)

OHA:	104338759(AGTR1)

NNT:	104401211(AGTR1)

SHAB:

115611592(AGTR1)

DPUB:

104309508(AGTR1)

PGUU:

104461862(AGTR1)

ACAR:

104528414(AGTR1)

CPEA:

104392326(AGTR1)

AVIT:

104268662(AGTR1)

CVF:	104284992(AGTR1)

RTD:	128911210(AGTR1)

CUCA:

104063418(AGTR1)

TEO:	104373078(AGTR1)

BRHI:

104491203(AGTR1)

AAM:	106485864(AGTR1)

AROW:

112962152(AGTR1)

NPD:	112947452(AGTR1)

TGT:	104576163(AGTR1)

DNE:	112981696(AGTR1)

SCAM:

104153213(AGTR1)

ASN:	102369755(AGTR1)

AMJ:	102569750(AGTR1)

CPOO:

109308574(AGTR1)

GGN:	109288136(AGTR1)

PSS:	102455529(AGTR1)

CMY:	102942297(AGTR1)

CCAY:

125643094(AGTR1)

DCC:	119861789(AGTR1)

CPIC:

101953639(AGTR1)

TST:	117882895(AGTR1)

CABI:

116839939(AGTR1)

MRV:	120372100(AGTR1)

ACS:	100555655(agtr1)

ASAO:

132770615(AGTR1)

PVT:	110073044(AGTR1)

SUND:

121927192(AGTR1)

PBI:

103064286

PMUR:

107284836(AGTR1)

CTIG:

120313107(AGTR1)

TSR:	106538577(AGTR1)

PGUT:

117678309(AGTR1)

APRI:

131200672(AGTR1)

PTEX:

113436883(AGTR1)

NSS:	113410303(AGTR1)

VKO:	123024734(AGTR1)

PMUA:

114597861(AGTR1)

PRAF:

128414645(AGTR1)

ZVI:	118093608(AGTR1)

HCG:	128351234(AGTR1)

GJA:	107124666(AGTR1)

STOW:

125437414(AGTR1)

EMC:	129331711(AGTR1)

XLA:	108707736 378523(agtr1.S) 398763(agtr1.L)

XTR:	100170183(agtr1) 101733812

NPR:	108794282 108797310(AGTR1)

RTEM:

120929622 120936613(AGTR1)

BBUF:

120993905 120997771(AGTR1)

BGAR:

122931463 122935012(AGTR1)

MUO:	115479209(AGTR1)

GSH:	117366712(AGTR1)

DRE:	100333455(agtr1b) 794575(agtr1a)

SRX:	107709880 107717774 107717851 107722527 107739124

SANH:

107663725 107680245 107681633 107688540

SGH:	107550594 107557561 107576085 107584999 107588039

CCAR:

109051050 109055900 109055910 109068275

CAUA:

113042244 113045909 113065963 113116419

CGIB:

127945824 127950581 128013037 128028883

PTET:

122328898(agtr1a) 122330099(agtr1b)

LROH:

127154992(agtr1a) 127155603(agtr1b)

OMC:	131522147(agtr1a) 131533539(agtr1b)

PPRM:

120476012(agtr1b) 120481880(agtr1a)

RKG:	130070898(agtr1a) 130084403(agtr1b)

MAMB:

125250148(agtr1a) 125258030(agtr1b)

CIDE:

127505715 127523775

MASI:

127431862 127434259 127441024 127442596

TROS:

130554661(agtr1a)

TDW:	130413288(agtr1b) 130417923(agtr1a)

MANU:

129426227(agtr1b) 129442253(agtr1a)

IPU:	108273841(agtr1b)

IFU:	128614952(agtr1b)

PHYP:

113545434(agtr1)

SMEO:

124383841(agtr1b)

TFD:	113651178(agtr1b)

TVC:	132845539(agtr1b)

AMEX:

103027188 103027843

CMAO:

118804788(agtr1a) 118815852(agtr1b)

EEE:

113584765

CHAR:

105889253(agtr1b) 105900560(agtr1a)

TRU:	101065754(agtr1)

TFS:

130514085

TNG:	GSTEN00023936G001

LCO:	104937220(agtr1)

NCC:	104964950(agtr1)

TBEN:

117497531(agtr1b)

CGOB:

115025727(agtr1)

PGEO:

117465692(agtr1b)

GACU:

117549896(agtr1b)

EMAC:

134858003(agtr1b)

ELY:	117264461(agtr1b)

EFO:	125881672(agtr1b)

PLEP:

121960597(agtr1b)

SLUC:

116053756(agtr1b)

ECRA:

117938087(agtr1b)

ESP:	116672342(agtr1)

PFLV:

114549432(agtr1)

GAT:	120811966(agtr1b)

PPUG:

119199007(agtr1b)

AFB:	129110899(agtr1b)

CLUM:

117749684(agtr1b)

PSWI:

130206543(agtr1b)

MSAM:

119910417(agtr1b)

SCHU:

122866663(agtr1b)

CUD:	121527076(agtr1b)

ALAT:

119008627(agtr1b)

MZE:	101480357(agtr1)

ONL:	100702961(agtr1)

OAU:	116314466(agtr1b)

OLA:	101170058(agtr1)

OML:	112151103(agtr1b)

CSAI:

133422908(agtr1b)

XMA:	102227070(agtr1)

XCO:	114137076(agtr1)

XHE:	116711776(agtr1)

PRET:

103456547(agtr1)

PFOR:

103140419(agtr1)

PLAI:

106950254(agtr1)

PMEI:

106931586(agtr1)

GAF:

122824568

PPRL:

129364494(agtr1b)

CVG:	107096468(agtr1)

CTUL:

119788896

GMU:	124857672(agtr1b)

NFU:	107382808(agtr1)

KMR:	108230521(agtr1b)

ALIM:

106513363(agtr1)

NWH:

119426883

AOCE:

111579241(agtr1) 111581992

MCEP:

124995725(agtr1b)

CSEM:

103377268(agtr1)

POV:	109629586(agtr1)

SSEN:

122773663(agtr1b)

HHIP:

117753690(agtr1b)

HSP:	118098738(agtr1b)

SMAU:

118291298(agtr1b)

LCF:	108881687(agtr1b)

SDU:	111237875(agtr1)

SLAL:

111656273(agtr1)

XGL:	120789830(agtr1b)

HCQ:	109519485(agtr1)

SSCV:

125985926

SBIA:

133492996(agtr1b)

PEE:	133396347(agtr1b)

PTAO:

133470545(agtr1b)

BPEC:

110155322 110170085(agtr1)

MALB:

109961497(agtr1)

BSPL:

114854618(agtr1b)

SJO:	128382618(agtr1b)

SASA:

106579762 106590686

STRU:

115148957 115195314

OTW:	112216162 112227449 121843335

OMY:	110490877 110535159

OGO:

123990316

ONE:	115123270(agtr1)

OKI:

109877912

OKE:

118377379

SALP:

112073876 112074818

SNH:	120027934 120038058

CCLU:

121549503 123490770

ELS:	105026597(agtr1)

SFM:	108934912(agtr1)

PKI:	111850479(agtr1)

AANG:

118226629(agtr1b) 118230825

LOC:	102696402(agtr1)

PSPA:

121323531 121326489

ARUT:

117406812 117416886(agtr1a) 117423670

PSEX:

120533703(agtr1a)

LCM:	102347667(AGTR1)

CMK:	103184450(agtr1a)

CPLA:

122556173(agtr1a)

HOC:	132821772(agtr1a)

LERI:

129703332(agtr1a)

PMRN:

116952498

LRJ:	133353827 133360096

BBEL:

LPIC:

HRF:

CVN:

OED:	125654010 125665850

DPOL:

127851307

OBI:

106868170

OSN:

115230975

XEN:	124455649 124455759

HSY:

130622133

» show all

Reference

PMID:7688227

Authors

Ji H, Sandberg K, Zhang Y, Catt KJ

Title

Molecular cloning, sequencing and functional expression of an amphibian angiotensin II receptor.

Journal

Biochem Biophys Res Commun 194:756-62 (1993)
DOI:10.1006/bbrc.1993.1886

Sequence

[xla:398763]

Reference

PMID:1567413

Authors

Bergsma DJ, Ellis C, Kumar C, Nuthulaganti P, Kersten H, Elshourbagy N, Griffin E, Stadel JM, Aiyar N

Title

Cloning and characterization of a human angiotensin II type 1 receptor.

Journal

Biochem Biophys Res Commun 183:989-95 (1992)
DOI:10.1016/S0006-291X(05)80288-8

Sequence

[hsa:185]

LinkDB

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