KEGG   ORTHOLOGY: K06005
Entry
K06005                      KO                                     
Symbol
SAP
Name
candidapepsin [EC:3.4.23.24]
Pathway
map04613  Neutrophil extracellular trap formation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K06005  SAP; candidapepsin
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K06005  SAP; candidapepsin
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.24  candidapepsin
     K06005  SAP; candidapepsin
Peptidases and inhibitors [BR:ko01002]
 Aspartic peptidases
  Family A1: pepsin family
   K06005  SAP; candidapepsin
Genes
PIC: PICST_63754
PGU: PGUG_03958
SPAA: SPAPADRAFT_51269
LEL: PVL30_001015(SAP98) PVL30_002079(SAP8_2) PVL30_002517
CAL: CAALFM_C104870WA(SAP7) CAALFM_C203670WA(SAP99) CAALFM_C203680WA(SAP98) CAALFM_C302510CA(SAP8) CAALFM_C303870CA(SAP9) CAALFM_C305230WA(SAP3) CAALFM_C404470WA(SAP10) CAALFM_C602710CA(SAP6) CAALFM_C603030WA(SAP5) CAALFM_C603490CA(SAP1) CAALFM_C603500CA(SAP4) CAALFM_CR07800WA(SAP2)
CTP: CTRG_00096 CTRG_00264 CTRG_00700 CTRG_02113 CTRG_02432 CTRG_02621 CTRG_02698 CTRG_02710 CTRG_02711 CTRG_03750 CTRG_04491
COT: CORT_0B01090 CORT_0B03690 CORT_0B03810 CORT_0B03820 CORT_0B03830 CORT_0B03840 CORT_0B03850 CORT_0B03860 CORT_0B06860 CORT_0E04800 CORT_0E04810 CORT_0F00880 CORT_0F03710 CORT_0G02030 CORT_0G02040
CDU: CD36_04610(SAP7) CD36_18360(SAP99) CD36_18370(SAP98) CD36_33460(SAP2) CD36_44180(SAP10) CD36_63420(SAP6) CD36_63430(SAP1) CD36_82480(SAP8) CD36_83850(SAP9) CD36_85220(SAP3)
CTEN: CANTEDRAFT_101871 CANTEDRAFT_112537 CANTEDRAFT_113142 CANTEDRAFT_115143 CANTEDRAFT_118876
CLU: CLUG_04798
 » show all
Reference
PMID:9043112
  Authors
Smolenski G, Sullivan PA, Cutfield SM, Cutfield JF
  Title
Analysis of secreted aspartic proteinases from Candida albicans: purification and characterization of individual Sap1, Sap2 and Sap3 isoenzymes.
  Journal
Microbiology 143 ( Pt 2):349-56 (1997)
DOI:10.1099/00221287-143-2-349
Reference
  Authors
Kvaal C, Lachke SA, Srikantha T, Daniels K, McCoy J, Soll DR
  Title
Misexpression of the opaque-phase-specific gene PEP1 (SAP1) in the white phase of Candida albicans confers increased virulence in a mouse model of cutaneous infection.
  Journal
Infect Immun 67:6652-62 (1999)
  Sequence
Reference
PMID:1879921
  Authors
Ganesan K, Banerjee A, Datta A
  Title
Molecular cloning of the secretory acid proteinase gene from Candida albicans and its use as a species-specific probe.
  Journal
Infect Immun 59:2972-7 (1991)
DOI:10.1128/IAI.59.9.2972-2977.1991
  Sequence
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