KEGG   ORTHOLOGY: K12711
Entry
K12711                      KO                                     
Symbol
novM, cloM, couM
Name
L-demethylnoviosyl transferase [EC:2.4.1.302]
Pathway
map00401  Novobiocin biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R06767  
R06770  dTDP-4-O-demethyl-beta-L-noviose:novobiocic-acid 7-O-[4-O-demethyl-L-noviosyl]transferase
R06773  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00401 Novobiocin biosynthesis
    K12711  novM, cloM, couM; L-demethylnoviosyl transferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.302  L-demethylnoviosyl transferase
     K12711  novM, cloM, couM; L-demethylnoviosyl transferase
Other DBs
CAZy: GT1
Genes
NSPU: IFM12276_32170
SANL: KZO11_29590
SGRF: SGFS_016160
SCYE: R2B67_24655 R2B67_24840
SPHW: NFX46_24910(mtmGII)
SCAE: IHE65_08945
SSPN: LXH13_14010 LXH13_14045
STUD: STRTU_005087
NGV: CDO52_02205
NCG: KGD84_13355
AG: AAF67506(novM) AAG29785(couM) AAN65229(cloM)
 » show all
Reference
  Authors
Steffensky M, Muhlenweg A, Wang ZX, Li SM, Heide L
  Title
Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.
  Journal
Antimicrob Agents Chemother 44:1214-22 (2000)
DOI:10.1128/AAC.44.5.1214-1222.2000
  Sequence
Reference
  Authors
Pojer F, Li SM, Heide L.
  Title
Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics.
  Journal
Microbiology 148:3901-11 (2002)
DOI:10.1099/00221287-148-12-3901
  Sequence
Reference
  Authors
Freel Meyers CL, Oberthur M, Heide L, Kahne D, Walsh CT
  Title
Assembly of dimeric variants of coumermycins by tandem action of the four biosynthetic enzymes CouL, CouM, CouP, and NovN.
  Journal
Biochemistry 43:15022-36 (2004)
DOI:10.1021/bi048457z
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