| Entry |
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| Symbol |
asm10
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| Name |
N-methyltransferase [EC:2.1.1.-]
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| Pathway |
| map01110 | Biosynthesis of secondary metabolites |
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| Reaction |
| R09856 | S-adenosyl-L-methionine:N-demethylansamitocin-P-3 N-methyltransferase |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
K16038 asm10; N-methyltransferase
01051 Biosynthesis of ansamycins
K16038 asm10; N-methyltransferase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K16038 asm10; N-methyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide tailoring proteins
Methylase
K16038 asm10; N-methyltransferase
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| Genes |
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| Reference |
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| Authors |
Wu Y, Kang Q, Shang G, Spiteller P, Carroll B, Yu TW, Su W, Bai L, Floss HG |
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| Title |
N-methylation of the amide bond by methyltransferase asm10 in ansamitocin biosynthesis. |
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| Journal |
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| Reference |
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| Authors |
Spiteller P, Bai L, Shang G, Carroll BJ, Yu TW, Floss HG |
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| Title |
The post-polyketide synthase modification steps in the biosynthesis of the antitumor agent ansamitocin by Actinosynnema pretiosum. |
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| Journal |
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| Reference |
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| Authors |
Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG |
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| Title |
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum. |
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| Journal |
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| Sequence |
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| LinkDB |
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