KEGG   ORTHOLOGY: K17709
Entry
K17709                      KO                                     
Symbol
CYP2B6
Name
cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-]
Pathway
map00590  Arachidonic acid metabolism
map00830  Retinol metabolism
map00980  Metabolism of xenobiotics by cytochrome P450
map00982  Drug metabolism - cytochrome P450
map01100  Metabolic pathways
map05207  Chemical carcinogenesis - receptor activation
map05417  Lipid and atherosclerosis
Reaction
R07000  naphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07048  
R07050  
R07051  
R07052  
R08275  
R08285  
R08286  
R08287  
R08313  
R08324  
R08325  
R08326  
R08390  
R08391  
R08392  
R09441  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
   00982 Drug metabolism - cytochrome P450
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
Genes
HSA: 1555(CYP2B6)
PTR: 104003379 456052
PPS: 100984180(CYP2B6)
GGO: 101151678
PON: 100457779 100458142
NLE: 101179527
HMH: 116480657
MCC: 114675607 678687(CYP2B6)
MCF: 102124427(CYP2B6)
MTHB: 126942029
MNI: 105495315
CSAB: 103234720
CATY: 105597999
PANU: 101001292
TGE: 112617245 112617418
MLEU: 105542145
RRO: 104676093 104676096
RBB: 108536168 108536170
TFN: 117087868
PTEH: 111554026
CANG: 105507826
CJC: 100405958
SBQ: 101041829
CIMI: 108285668(CYP2B6)
CSYR: 103268360
MMUR: 105869127 105869130 105869132
LCAT: 123624287 123624291 123624292
PCOQ: 105820597 105820600
MDO: 100018958
 » show all
Reference
PMID:2573390
  Authors
Yamano S, Nhamburo PT, Aoyama T, Meyer UA, Inaba T, Kalow W, Gelboin HV, McBride OW, Gonzalez FJ
  Title
cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver.
  Journal
Biochemistry 28:7340-8 (1989)
DOI:10.1021/bi00444a029
  Sequence
[hsa:1555]
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