| Entry |
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| Name |
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| Definition |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC: 3.1.4.17 3.1.4.35]
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| Pathway |
| Purine metabolism | | Morphine addiction |
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| Disease |
| Autosomal dominant striatal degeneration (ADSD) |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
Metabolism
Nucleotide metabolism
00230 Purine metabolism
K18438 PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10
Human Diseases
Substance dependence
05032 Morphine addiction
K18438 PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10
Enzymes [BR:ko01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
K18438 PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
K18438 PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10
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| Other DBs |
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| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | NLE: | | MCC: | | MCF: | | CSAB: | | RRO: | | CJC: | | SBQ: | | MMU: | | RNO: | | CGE: | | NGI: | | HGL: | | CCAN: | | OCU: | | TUP: | | CFA: | | AML: | | UMR: | | FCA: | | PTG: | | AJU: | | BTA: | | BOM: | | BIU: | | PHD: | | CHX: | | OAS: | | SSC: | | CFR: | | BACU: | | LVE: | | ECB: | | MYB: | | MYD: | | HAI: | | RSS: | | PALE: | | LAV: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | CJO: | | APLA: | | TGU: | | GFR: | | FAB: | | PHI: | | CCW: | | FPG: | | FCH: | | CLV: | | AAM: | | ASN: | | AMJ: | | PSS: | | CMY: | | CPIC: | | ACS: | | PBI: | | GJA: | | XLA: | | XTR: | | DRE: | | IPU: | | TRU: | | TNG: | | LCO: | | MZE: | | OLA: | | XMA: | | CSEM: | | SASA: | | LCM: | | CMK: | | BFO: | | CIN: | | SPU: | | SKO: | | AAG: | | CQU: | | TCA: | | BMOR: | | PXY: | | PHU: | | DPX: | | ISC: | | CEL: | | CBR: | | NAI: | | BMY: | | LOA: | | LGI: | | CRG: | | OBI: | | OVI: | | NVE: | | ADF: | | HMG: | | TAD: | |
» show all
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| Reference |
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| Authors |
Omori K, Kotera J |
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| Title |
Overview of PDEs and their regulation. |
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| Journal |
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| Reference |
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| Authors |
Fujishige K, Kotera J, Michibata H, Yuasa K, Takebayashi S, Okumura K, Omori K |
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| Title |
Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A). |
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| Journal |
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| Sequence |
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| LinkDB |
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