KEGG   Klebsiella michiganensis M1: HR38_03210
Entry
HR38_03210        CDS       T03349                                 
Symbol
mrcA
Name
(GenBank) penicillin-binding protein 1A
  KO
K05366  penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
Organism
kom  Klebsiella michiganensis M1
Pathway
kom00550  Peptidoglycan biosynthesis
kom01100  Metabolic pathways
kom01501  beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:kom00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    HR38_03210 (mrcA)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    HR38_03210 (mrcA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:kom01003]
    HR38_03210 (mrcA)
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:kom01011]
    HR38_03210 (mrcA)
Enzymes [BR:kom01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.99  Transferring other glycosyl groups
    2.4.99.28  peptidoglycan glycosyltransferase
     HR38_03210 (mrcA)
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.16  Serine-type carboxypeptidases
    3.4.16.4  serine-type D-Ala-D-Ala carboxypeptidase
     HR38_03210 (mrcA)
Glycosyltransferases [BR:kom01003]
 Polysaccharide
  Bacterial polysaccharide (excluding LPS)
   HR38_03210 (mrcA)
Peptidoglycan biosynthesis and degradation proteins [BR:kom01011]
 Peptidoglycan biosynthesis and degradation
  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
   HR38_03210 (mrcA)
SSDB
Motif
Pfam: Transgly PCB_OB Transpeptidase DUF3502
Other DBs
NCBI-ProteinID: AIE67502
UniProt: A0A1Q8YSR8
LinkDB
Position
637182..639740
AA seq 852 aa
MKFVKYLFILAVCCVLLGAGSIFGLYKYIEPQLPDVATLKDVRLQIPMQVYSADGELIAQ
YGEKRRIPVTLQQMPPELIKAFIATEDSRFYEHHGVDPVGIFRAASVAMFSGHASQGAST
ITQQLARNFFLSPEKTLMRKVKEAFLAIRIEQLLNKDEILELYLNKIYLGYRAYGVGAAA
QVYFGKSVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRATARRNVVLSRMLSEGYITQSQY
DQARSQTIDASYHTPEIAFSSPYLSEMVRQEMVSRYGEQAYEDGYRVYTTITRKNQQAAQ
QAVRNNVLDYDMRHGYRGPEKVLWKVGETPWDNQKILDTLKKTPSTGPLSPAVVTSASPQ
EAVALMSNGTSVSLNMEGVRWARRFISDTQQGATPRKVNDVVQAGQQVWVRQVGSSWWLS
QVPDVNSALVSINPQNGAIIALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL
TLASMLNDVPISRWDAGSGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDY
AAEYLQRFGFPAQNIVRTESLALGSASFTPLQVARGYSVMANGGFLVSPYFISKIENDQG
GVIFEERPKIACPQCNIPVIYGDTPKSDVLENKDVEDVATSQDPQNPGVPPQPQLAQANQ
SLVAQSGAPEYAPHVINTPLAFLIKSALNTNIFGEPGWMGTGWRAGRDLQRHDIGGKTGT
TNSSKDAWFSGYGPGVVTSVWIGFDDHRRDLGRTTASGAIKDQISGYEGGAKSAQPAWDD
FMKNVLQGVPEEPLTPPPGIITVNIDRSTGQLASGGNSRAEYFIEGTQPTQQAVHEVGTT
ITDGGGETHELF
NT seq 2559 nt   +upstreamnt  +downstreamnt
gtgaagttcgtaaagtatctttttatccttgcagtctgttgcgtactgctgggagcaggc
tcgatttttggtctctataaatatatagagccgcagctccccgacgtcgcaaccctgaag
gatgtgcgcctgcagatcccgatgcaggtctatagcgcggatggcgagctgattgcgcaa
tatggcgaaaaacgccgtattcccgtcacgctgcagcaaatgccgcctgagctgataaaa
gcgtttatcgccaccgaagatagccgtttttatgagcaccatggcgttgatccggtcggg
attttccgcgcggccagcgtcgcgatgttctccggccacgcctcgcagggcgccagtacg
attactcagcagctggcgcgcaacttcttcctgagccctgagaagacgctgatgcgtaag
gtgaaagaagccttcctcgcgatccgcatcgagcagttgctcaataaagatgaaatcctt
gagctgtacctgaacaaaatctatcttggctaccgcgcctacggcgtcggcgcggccgcg
caggtctattttgggaaatccgtcgaccagcttacgctgagcgaaatggcggtcattgcg
ggcctgcctaaagcgccgtcgacgtttaacccgctctactccatggatcgcgcaaccgcc
cgccgcaacgttgttctctcacggatgctgagcgaaggctacatcacgcagtcgcagtac
gatcaggcgcgtagccagacgattgacgccagctaccatacgccggaaatcgccttctcc
tccccgtatcttagcgaaatggtgcgtcaggaaatggtcagccgctacggcgagcaggct
tatgaagacggttatcgcgtctacaccaccattacccgtaaaaatcagcaggccgcccag
caggcggtgcggaataacgtgctggattacgacatgcgccacggctatcgcggcccggaa
aaggtgctgtggaaggtgggcgaaacgccgtgggataaccagaaaatcctcgataccctg
aaaaaaaccccgagtaccggaccgctctctccggcggtagtcacttcggcaagcccgcag
gaagccgtcgcactcatgagcaacggcacctcagtgtcgctgaatatggaaggcgtccgc
tgggcgcgtcggtttatctctgatacccaacagggcgccacgccgcgtaaagtgaacgat
gtggtgcaggccgggcagcaggtgtgggtccgccaggtgggtagcagctggtggctatcg
caggtgcctgatgtcaactcggcgctggtatcgatcaacccgcaaaacggggcgatcatt
gcgctggtcggcggcttcgatttcaaccagagcaagttcaaccgcgcgactcaggcgctg
cgccaggtcggttctaacattaagccgttcctctacacagcggcaatggataaaggctta
acgctggcgagcatgctcaacgatgtgccgatttcccgctgggatgccggctccggctcc
gactggcggccaaaaaactccccgccgcagtatgcgggccctatccgcctgcgtcagggg
ctgggtcaatcaaagaacgttgtcatggttcgcgcgatgcgcgccatgggtgtggactac
gcggcagagtatcttcagcgcttcggcttcccggcgcagaacatcgtgcggacagaatcg
ctggcgctgggctccgcgtctttcaccccgcttcaggttgctcgcggctattcggtgatg
gctaacggcggtttcctggtcagcccttatttcatcagcaaaattgagaacgatcagggc
ggcgtcatttttgaagagcggccaaaaattgcctgcccgcagtgcaatattccggtgatt
tatggcgatacgccgaagtccgatgtgctcgagaacaaagacgttgaggacgtagcgacc
tctcaggacccgcaaaaccccggcgttcctccgcagccgcagctggcgcaggcgaaccag
tcgctggtggcgcaaagtggcgcaccggagtatgcgccgcacgtgatcaacaccccgctg
gcgttcctgattaaaagcgccctgaacactaacatcttcggcgaaccgggctggatgggc
accggctggcgagcgggccgcgatctgcagcgtcacgatatcggcggcaaaaccgggacc
accaacagttcaaaagatgcgtggttctcggggtacggccctggcgtggtgacgtcggta
tggatcggcttcgatgaccaccgtcgcgaccttggccgcaccactgcctccggggcaatc
aaagatcagatatcaggctatgaaggcggcgccaaaagcgctcagccggcctgggatgac
tttatgaaaaacgtgctgcaaggcgtaccggaagaacctcttacgccgccgccgggtatt
attacggtcaacattgaccgcagtaccggtcagttggccagcggcggtaacagccgcgct
gagtactttattgagggcactcagcctacccagcaggcggttcatgaagtcggcaccacc
attaccgatggcgggggggaaacccacgaactgttctga

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