Klebsiella pneumoniae Kp52.145: BN49_3620
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Entry
BN49_3620 CDS
T05281
Symbol
clbJ
Name
(GenBank) highly similar to putative peptide synthetase from Escherichia coli O6 (tr|Q8FGC1)
KO
K26578
colibactin biosynthesis nonribosomal peptide synthase
Organism
kpnk
Klebsiella pneumoniae Kp52.145
Pathway
kpnk01054
Nonribosomal peptide structures
Brite
KEGG Orthology (KO) [BR:
kpnk00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01054 Nonribosomal peptide structures
BN49_3620 (clbJ)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
kpnk01008
]
BN49_3620 (clbJ)
Polyketide biosynthesis proteins [BR:
kpnk01008
]
Polyketide synthase (PKS)
PKS-NRPS hybrid
Bacterial type (modular)
Colibactin synthetase
BN49_3620 (clbJ)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AMP-binding
Condensation
PP-binding
Nitroreductase
AMP-binding_C
Motif
Other DBs
NCBI-ProteinID:
CDO15372
LinkDB
All DBs
Position
complement(3777113..3784435)
Genome browser
AA seq
2440 aa
AA seq
DB search
MTIHHAALARMLPAEKKEKLLRQLAQSGVSPSRIPIIKADPAQAIPLSFNQERLWFLQKY
DSTATNYNLYVVYRLHGVVDMPMLTEALRHVQARHAILRTRIIVRNDRPCQVIDDASSLV
LDTVTLAAQAPTSALDAVIQQVINTRFDLARGPLWGVTQIIQPDQGCHLVFCAHHIIIDG
ISLRLLFDELQQQYARLHAGNETSLPPPPLQYADYAFWQREWFQDTLLANELAYWRARLQ
DAPLLSTFPSLHPRPAQPSTHGSRFSITLDETLSLALKHVARTQETTPFVLMLTAFQLVL
MRYAQQQRLVIGMPVSGRIRPELQSSIGYYASTAVIYTDFNGVEVGREALQRVKASVKET
QGRQQLPFENLVNMLDLPRSLSHSPLFQILYIYHNHVTPRAFTLAGAYWEQVTYHNQTVK
YDMTVEVFQNDATFDVSFEYDLGLYDADVVKQIAEALRQHCLSLTSSLETPIRAIPLHAP
ETATPRRDPLNATNVPWLGPQDVLRIIEQRCVQHPKQLAIQQHDGTLTYAELWARVQFIA
MRFRAHGIQPGDRIGVLLPRHRDVIATMLATWFVGACYVPFDIHQPAARLQRLMQRARLV
CLVVRQPGEWGEIVQLSLPELMQDMSNTIRYSTPCALLPDMQAYLLFTSGSTGEPKGVCV
VHRGLLNLLLDMQRTFAVGPQDRLLSVTTPTFDISFLEYLLPLISGASLYLTEAERAADS
FRMIPLIADYRPTLMQATPSFWHGLLMAGWRGDPELCVLAGGEALPTKVAEELLRCCGSL
WNLYGPTETTIWSLKSQITQAENITLGAPIANTRIYILDNEGHPVPQGVDGELYIAGDGV
AQGYDGQPELNAQFFLSEPGVPGGRMFRTGDLVRSDAQGQLFFVGRKDSQIKLRGYRIEL
GEIERTLARHPHVDAAVVACIERAPLHKALAAFIITSEPPSLFEQLKNELRQQLPDYMVP
TLWQRVADFPNTDNGKIDRKRLAENFVADSSLVSPQTQALSDTEQMLLALWMRYLPIKNV
DPECDFFRLGGHSLLAVTLVAEINRTFHCALTLKDIFHYSTLRALSARIAQQSITDAAAS
QDDWVIVHDPEHRHQPFPLTDVQRAYWLGRQTGATSIATHIYHEFDVEHFNVTRFTHAVN
ALIARHEMLRARVLPDGTQQILAQVPAYQLEQRDLSALSPNARNDALMAIRDRLSHHVHP
ADRWPLFDFSYSACTAQHGRLHFSLDLLIADALSMRTLQQELMMLYREPHVSLPLLPFSF
RDYVQALLVEQASEAYARDQAYWQRALPQLYGPPTLPVQGDLAQLSAIRFVRRRHRLSAH
NWGVLSALAQRTRITKTALLLTVFSQVLARWSLSPTFTLNLTLFNRPQGYPNAEAVIGDF
TAVSLLNVCYDSQYSYAHNAQRIQVQLWEDLEHRRFSGIRASEALIHSGRFHAPMPVVFT
SMLDIDGETTAQDPRDTTRFTLCPDANITQTPQVWLDHQVIELAGELHFNWDAVEQLFDT
TLLDQMFGAYCHALQALVAMPQSWWGVNSSLALPTISAPVTQAPAPTALLHHGLLRQAAL
TPQETALISPIRELTYRQLSTAADHVARALLALGVQHGDRVAVVMEKGWQQIAAVHGILR
LGAVYLPVDPVLPPQRRQLLLTVGEVRVQVTQPGLTQLEPSLPVLIIDDGMLDTPAAPLP
EVAGDVTDLAYIIFTSGSTGTPKGVMIDHRAAMNTLEDINERFGLNAQDRVFGLSSLSFD
LSVYDAFAPFMVGAALVLPEAGREKDPRHWQTVMAHGHVSVWNAVPALMQMLCEYHSGDR
MSYPTLRLALLSGDWIPLTLPEQMRERLNETMDIISLGGATECAIWSVYYPIGEVESTWT
SIPYGRGLRNQPVYVLNAQLEECPVGVEGEICIGGMGLAQGYLNDAEKTVASFVWREASG
ERIYRTGDRGRYFADGQVAFLGRNDTQVKVNGYRIELGEIERCIARHPDVEQSVVVAVGN
SQHRRLVAFAKLHDRHQAQALQAKEAEAAALAQGIIVNPAQRLAFKLKEPHIRALDGLGI
ALTVPADSTRYIKRRSYRHFSAQKTTLAQLGQLLSGLGQMRLPGLPFAKYAYASAGGLYP
VQTYVYLHPDKIEEGVSGIYYFDPRQSCLMPVAPEVELNSGFHAGPNQSIADRAAFTLFM
VADMAVISPFYGQEAAWHFSVMEAGTLCHLLEEDAPRYGLGLCQLGMADFSAVASHFQLS
PHHRYVHCTVGGAIGQEAASAAALLRDFSTYEKPKETAASLDMQSYKDAMLRGLRQQLPD
YMVPSDLMLATDFPLTANGKLDRQKLQLQGEQIAHQRDGVGPIQVDSALQQRLVALWQEV
LGVSHVSVEDDFFSLGGSSIELVRIQQALEAIIGQEIPIVDLFRLPTIADVARYLDEQLH
NLPAAHDIVLAQAEVSQVSAARENLALRRKRAQQGEKGDE
NT seq
7323 nt
NT seq
+upstream
nt +downstream
nt
atgacgatacatcatgccgcattggcgcgaatgttaccggcggaaaaaaaggaaaagcta
ttacgacagttggcgcaatcaggcgtgtcgcccagccgcattcccatcatcaaagcggat
ccggcgcaggcaatcccgctgtcgtttaatcaggagcggttgtggtttttgcaaaaatac
gacagtaccgccactaactacaacctgtatgtggtgtatcgtttgcatggcgtggtggat
atgccgatgctcacggaggcattgcgccatgtgcaagcacgccacgccatcttgcgtacc
cgtatcatagtacgtaacgatcggccttgccaggtgatagatgatgcgtcttcgttagtt
ctcgatacggtcacgctggcagcgcaggccccaacttcagcgctagatgcggtaattcag
caggtgataaacacccggttcgatctggcacgcggtcctctgtggggggtaactcagatt
attcaacccgatcaaggttgtcatttggtgttttgcgcgcaccatatcatcatcgacggt
atctcgttacggctattgttcgatgagttacagcagcagtatgctcgattgcatgctggt
aatgaaacgtcgctgcctccgccgccgctgcaatatgccgattatgccttctggcagcgc
gaatggttccaggataccttgctggcgaacgaacttgcctactggcgtgcgcgtttgcaa
gacgcgcctctactgtcgacatttccatcgctgcacccgcgcccggcacaaccctctaca
catggttcccggttcagcatcaccctggatgaaacattaagcctcgcgttgaaacacgta
gcccgcacgcaggaaacaacgccgttcgtgctgatgctgactgccttccaactggtgctg
atgcgttacgctcagcaacagcgattggtgataggcatgccagtatcggggcgcattcgc
ccggaattgcagagtagcattggttattatgccagcactgcggttatctacaccgatttt
aacggggttgaggtagggcgcgaggcgctccagcgtgtgaaggccagcgtgaaagagacg
caggggcgccagcaactgccgtttgaaaacttggtgaatatgctggatctccctcgcagc
ctttcccattcgccgttgttccagatcctctatatctaccataaccacgtgaccccacgc
gcttttaccttggctggtgcgtattgggagcaggtgacgtatcacaatcagaccgtcaaa
tacgacatgacagtcgaggtgttccaaaacgacgccacgttcgacgtctcctttgagtac
gatttggggttatacgatgctgatgtggtgaagcagattgccgaggcgctgcgtcagcac
tgcttatcgttgacatcatcactggagaccccgataagggcgatccctctgcatgcaccg
gagaccgcaacgccgcggcgtgatccgctcaacgccactaacgtcccgtggctcgggccg
caggatgtgctgcgtatcattgaacagcgctgtgtgcagcacccaaagcaactggcaata
cagcagcatgacggcacactgacctacgctgagctctgggcgcgtgtgcagttcatcgcg
atgcgttttcgagcgcatggcatacaaccgggcgatcgtattggcgtgctgttgccacgt
cacagggatgtgattgcaaccatgttggcgacgtggtttgtgggggcgtgctacgtgccg
ttcgatattcatcagcctgccgcgcgtttgcaacgccttatgcaacgcgcgcgtttggtc
tgtctggtggtccgtcagccgggagagtggggtgaaattgtacaactgtcgttgccggaa
ttgatgcaggacatgtcgaatacgatccggtattctacaccttgcgcgctgttgccggat
atgcaggcctacctgttgtttacctccggcagtaccggtgaacctaaaggcgtgtgcgtt
gttcaccgcgggttgctgaacttgttgttggatatgcagcgtacctttgcggttggcccg
caagaccggctgctctcggtgacgacgccaacatttgatatctcattcttggagtatctg
ttgccgctgatctccggtgcgagtctctatctgacagaggcggaacgcgccgcagacagc
ttccgtatgattccgctgattgccgactatcgaccaacgctgatgcaggcgacgccctcg
ttctggcacgggctgttgatggcgggttggcgtggcgacccggaactatgtgtgctggca
ggcggtgaagcgctgccaacgaaagtggcggaagaactgttgcgctgttgtggttcactg
tggaacctctacggtcccaccgaaacaaccatttggtcgctgaaatcgcagataacccaa
gcggaaaacatcaccctcggcgctcccattgccaatacccgtatatacattctggacaat
gagggccatccagtgccgcaaggcgttgacggcgagctttacatcgccggggatggtgtg
gcgcaagggtatgatgggcagcctgagttgaacgcacagttcttcttgtcagaaccaggg
gtccccggtggcaggatgttccgcactggcgatctggtcaggagtgatgcgcaggggcag
ttgttttttgttgggcgcaaagatagccagatcaaactgcgcggttatcgtattgagtta
ggcgaaattgaacggacgttggcacggcatccgcatgtggacgccgcggtggtggcctgt
attgaaagagcaccgttacacaaagcactggcagcattcatcatcaccagcgagcctccc
tcgctattcgagcaactgaaaaacgagcttcggcagcaactgccagactatatggtgcca
acgctgtggcagagggtggccgacttcccgaacactgacaacggtaaaatcgatcgtaag
cggttagcggaaaatttcgttgccgatagctcccttgtgtcgccgcagacgcaagcgctg
agcgacacggaacagatgttgctggcgctgtggatgcgctatttgccgataaaaaacgtc
gatcctgagtgcgatttctttcgcttggggggacattcgctgttggcggtaacgttggta
gcagagatcaaccgcacttttcactgcgccttgaccctgaaggacattttccactactcc
acactacgggcactgagtgcgcgtattgcacagcaatctatcacggatgctgccgcgtct
caggatgactgggtgatagtgcacgaccctgagcatcgtcatcaaccgttcccattgacg
gatgttcagcgcgcctactggcttggacgacagacgggtgctacctcgatcgcgacccac
atctaccatgaatttgacgtagaacactttaatgttacgcgttttacccatgcggtgaat
gcgctgatcgctcgccatgaaatgctacgtgcgcgggtactccccgacggtactcagcag
attctggcgcaagtgccggcgtatcagttagagcagcgcgatctgagtgctttgtcccct
aacgcacgaaacgatgccttgatggcgatccgggatcggctgtcgcatcatgtgcatccc
gcagatcgttggccgctgtttgatttcagttattcggcttgcacggcgcaacatggccgc
ttgcatttcagtctcgatctgctgattgccgatgctctgagtatgcgcacgctacagcag
gagttgatgatgctgtaccgtgagccccatgtgtcactgccgttgctaccgttctctttt
cgtgactacgtgcaggcgctgttggtagagcaggcgagtgaagcctatgcacgcgatcag
gcctattggcaacgggcgctgccgcagctgtatggcccaccaacgctgcccgtacagggc
gatttggcgcaactgtctgcgatcaggttcgtacgtcgccgtcatcggctgtcagcccac
aactggggagtgctgagcgcgctggcccaacgcacacgtatcaccaagacggcattgttg
ttgacagtctttagccaagtgctggcacgttggagccttagcccgacgtttacgctcaat
ctgacgttgttcaaccgcccgcagggttaccccaacgcagaggcagttattggtgatttt
accgctgtcagcttgctgaatgtttgttacgacagccagtactcttatgcccacaacgct
cagcgtattcaggtgcaactgtgggaagatctcgaacatcgtcgtttcagtgggatccgc
gccagcgaggcgctgatccatagcggtcgtttccatgcgccgatgccggtggtattcact
agtatgttggatatcgatggggagacgactgcgcaagaccctcgggacacaacccgtttt
actctgtgtccggacgccaatattacccaaacaccgcaggtgtggctcgatcaccaggtg
atcgagttggctggggagttgcatttcaactgggacgcggtcgagcaactgtttgatacc
acgctgctggatcagatgtttggtgcttattgtcatgcgctgcaggcgctggttgccatg
ccgcaaagttggtggggggtaaatagttctctggcgctgcccaccattagtgcaccggtc
acgcaggctcctgcacctacggccttgttgcaccatgggttactgcgtcaggcagcactg
acgccacaggaaactgcgctgatcagtcctatccgtgaattgacctatcgccaactgtcg
acggcggcggatcatgtggcccgcgccctgttagcgctgggcgtgcagcatggcgatcgc
gtggcggtggtgatggaaaaaggctggcagcagattgccgccgtacacggcattttacga
ctgggtgcggtctatctgccagtggatccggtgctaccgccacagcgtcgccagcttttg
ctgacggtgggcgaggtgcgggtacaagttacgcagccgggtctcacgcaattggagccg
tcgctgcctgtgctgatcatcgacgacggaatgctggacacgcctgctgcgccgttgcct
gaagtggctggggatgtcacggatctggcctatatcattttcacttccggctccaccggt
accccgaaaggagtgatgatcgaccaccgtgcggccatgaacacgctggaagacatcaac
gaacgctttggcctcaatgcgcaggatagggtgttcgggctgtcatcattgagctttgac
ctgtcggtttacgatgcctttgcgccttttatggtgggtgcagcgctggtactgccggaa
gcaggacgggaaaaagatccgcgtcattggcagacagttatggcacacggtcatgtaagc
gtctggaatgcagtgcccgcactgatgcagatgctgtgcgaataccacagcggcgatcgg
atgagttatccgacgttgcgtctggcactgttgagcggcgactggatcccgctaacgtta
ccggagcagatgcgcgagcggctcaatgaaacgatggacatcatcagtctgggtggagcg
accgagtgcgccatctggtcggtctactacccgataggtgaggtggaatcgacgtggacc
agtattccctacggtcggggtctgcgcaaccagccagtatacgtgctaaatgcgcaactg
gaggaatgtccggtcggggtggaaggagagatttgcattggcgggatggggctggcacaa
ggctacctgaacgatgcagagaaaacggtggcgagctttgtctggcgcgaagcgagtggt
gagcgaatttaccgcactggggatcgcgggcgctactttgctgacgggcaagtcgccttt
ttggggcgcaacgatacccaagtgaaggtgaatggttaccgtatcgaactgggggaaatc
gagcgctgcattgcgcgacatcccgatgtggagcagtcagtggtggtggcagtgggtaat
tctcaacatcgtcggttggtcgcttttgccaaactgcacgatcgccaccaggcgcaggca
ttgcaagctaaggaagcggaggcggcggcactggcgcagggtattattgtgaatccggca
cagcgtctagcgttcaaactcaaggagccacatattcgcgcgctggatggtctgggcatt
gcactgacggtaccggcggatagcacacgttacatcaaacgccgcagctatcgtcatttc
agcgcgcaaaaaaccacgctggcacagttggggcaattgctgtcgggcttggggcagatg
cgtctgcccggtctaccttttgccaagtatgcctatgcgtctgccggggggctatacccg
gtgcaaacatacgtgtacctgcatccagacaagatcgaagagggagtatccggtatttac
tacttcgacccgcgacagagctgtcttatgccggtagcaccagaagtcgagctgaacagt
ggttttcatgccggacctaatcagtctattgccgatcgggcggcattcacgctgtttatg
gtggctgatatggcggtgatctcgccattctatgggcaagaggcagcttggcacttctcg
gtgatggaagcaggtactctctgccatttactggaagaagatgcgccgcgctacggattg
gggctgtgccaacttgggatggcagacttttccgctgtggcatcgcattttcaattgtcg
ccacatcatcgctatgtccattgcaccgtggggggcgcgatagggcaagaggcggcaagt
gctgcagcattgctgcgcgatttctccacctatgagaaaccgaaggaaaccgctgcgtcg
ctggacatgcagagctacaaagatgccatgctgcgcggcctgcgtcagcaactgcctgac
tatatggtgccgagcgatctgatgttagcgaccgattttccgttaaccgctaacggcaag
ctagatcggcaaaaattacagctgcagggcgaacaaattgcccaccagcgtgacggcgtg
ggtccaatccaggtggacagtgcgttacaacagcggctggtggcgctctggcaagaggta
ctcggcgtgagccacgtgtcggtcgaagacgatttcttctcgctggggggcagttctata
gaattggtgcgtattcagcaggctcttgaggcgattatcgggcaggagattcccattgtc
gatctgttccgtctgccaaccatcgcggatgtggcgcgttaccttgatgagcaactgcac
aatctacccgccgcccacgatatcgtattagcgcaggctgaggtttcgcaggtcagcgct
gcgcgcgagaatctggcgttgcggcgaaaacgtgcccaacagggagaaaagggcgatgag
tga
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