KEGG   Loxodonta africana (African savanna elephant): 100669094Help
Entry
100669094         CDS       T04351                                 

Gene name
HK1
Definition
(RefSeq) hexokinase 1
  KO
K00844  
hexokinase [EC:2.7.1.1]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
Glycolysis / Gluconeogenesis
Fructose and mannose metabolism
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Neomycin, kanamycin and gentamicin biosynthesis
Metabolic pathways
Carbon metabolism
HIF-1 signaling pathway
Insulin signaling pathway
Type II diabetes mellitus
Carbohydrate digestion and absorption
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:lav00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100669094 (HK1)
   00051 Fructose and mannose metabolism
    100669094 (HK1)
   00052 Galactose metabolism
    100669094 (HK1)
   00500 Starch and sucrose metabolism
    100669094 (HK1)
   00520 Amino sugar and nucleotide sugar metabolism
    100669094 (HK1)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    100669094 (HK1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    100669094 (HK1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    100669094 (HK1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100669094 (HK1)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    100669094 (HK1)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100669094 (HK1)
Enzymes [BR:lav01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     100669094 (HK1)
Membrane trafficking [BR:lav04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    100669094 (HK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
LinkDB All DBs
Position
Un
AA seq 919 aa AA seqDB search
MIAAQLLAYYFTELKDDQVKKIDKYLYTMRLSDETLLDIMARFRSEMKSGLSRDSNPTAT
IKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVDHEQHQNVRMESEVYDTPENIIH
GSGSQLFDHVAECLGDFMEKKKIKDKKLPVGFTFSFPCQQSKIDEGILITWTKRFKASGV
EGADVVKLLDKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YIGELVRLILVKMAKEGLLFEGRITPELLTKGKFNTSDVSAIEMNKEGLHNAKEILTRLG
VEPSHDDCISVQHVCAIVTFRSANLVAATLGAILCRLRDNKGTPRLRTTVGVDGSLYKMH
PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFRLT
KEMLMEVKKRMRAEMELGLKKATHEKATVKMLPSFVRSTPDGTEHGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYTIPIEVMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGF
TFSFPCKQESLDAGILITWTKGFKATDCVGHDVTTLLKDAIKRREEFDLDVVAVVNDTVG
TMMTCAYEEPTCEVGLIVGTGSNACYMEEMRNIEMVEGTDGQMCINMEWGAFGDNGCLDD
IRTGYDKLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRG
IFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAELCGAGMAA
VVDKIRENRRLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPQCNVSFLLSEDGSGKG
AALITAVGVRLRGEVPPTS
NT seq 2760 nt NT seq  +upstreamnt  +downstreamnt
atgatcgccgcgcagctcctggcctactacttcaccgagctgaaggatgaccaagtcaaa
aagattgacaagtatctctataccatgcggttatccgatgaaactctgttggatatcatg
gctcgcttcaggagtgagatgaagagtggcctctcccgggattctaatccaacagccaca
atcaagatgttgccaacatttgtaaggtccattcctgatggttcagagaagggagatttc
attgccttggatcttggtgggtcttcctttcgaattctacgggtgcaagtggatcacgag
cagcatcaaaatgttcgcatggagtctgaggtttacgacacccccgagaacatcatacac
ggcagtggaagccagctttttgatcacgtcgctgagtgcctgggagacttcatggagaaa
aagaaaatcaaggacaagaaattacctgtgggattcacgttttctttcccctgccaacaa
tccaaaattgatgagggcatcctgatcacctggacaaagagatttaaagcgagtggagta
gagggtgcagatgtggtgaagctgctggacaaagccatcaagaaacgaggggactatgac
gccaacattgtggccgtggtgaacgacacagtggggaccatgatgacctgtggctacgat
gaccagcattgtgaagttggcctgatcattggcactggcaccaatgcttgctacatggag
gaactgaggcacattgacctggtggaaggcgatgaggggaggatgtgcatcaacacggag
tggggggcctttggggacgacgggtccctagaagacatccggaccgagtttgaccgagag
atagaccggggctcccttaatccgggaaagcagttgtttgagaagatggtcagtggcatg
tacatcggggagctggttcgactgatcctggtcaagatggccaaagagggtctcttattt
gaagggcggatcaccccggagctacttaccaaaggaaagttcaacaccagcgatgtgtca
gccatcgaaatgaataaggaaggcctccacaatgccaaagaaatcctgacccgtctggga
gtggaaccgtctcatgacgactgtatttcagtccagcacgtgtgcgccattgtcacgttt
cgctcggccaacctggtggctgcaacgctgggtgccatcttgtgccgccttcgtgataac
aagggcacacccaggctgcggactacggttggtgtcgacggatctctatacaagatgcac
ccacagtattcccggcgtttccacaagaccctgaggcgcctggtgccggactcagatgtg
cgtttcctgctgtcggagagcggcagtggcaagggagccgccatggtgaccgcagtggct
taccgcctggccgagcagcaccggcagatcgaggagaccctggcccacttccgcctcacc
aaggagatgctgatggaggtgaagaagcggatgcgggctgagatggagttgggactgaag
aaggcgacccatgagaaggccactgtcaagatgctgccctcctttgtccggagcactcca
gatgggactgagcacggtgacttcttggccctcgaccttggaggaacgaacttccgcgtc
ctgctggtgaagatccgcagtgggaagaagaggacagtggaaatgcacaacaagatctac
accattcccattgaagtcatgcagggcaccggggaagagctgtttgaccacatcgtttcc
tgcatctccgacttcctggactacatgggcatcaaaggccccagaatgcctttgggcttc
accttctcctttccctgcaagcaggaaagcttggatgcgggtatcttgatcacctggaca
aagggcttcaaggcaactgactgtgtggggcacgatgtaaccaccctactaaaggatgca
ataaaaaggagagaggaatttgacctggacgtggtggctgtggtgaacgacacggtgggc
accatgatgacctgtgcttatgaggagcccacctgtgaggtcggactcatcgtaggaacg
ggcagcaatgcctgctacatggaagaaatgaggaatattgagatggtggaagggactgat
gggcaaatgtgtatcaacatggaatggggtgcctttggggacaacggctgtctggatgat
atccgaacaggctatgataagttggtggatgaatattctctaaacgctgggaaacaaagg
tatgagaagatgatcagcggcatgtacctgggggagatcgtccgcaacatcctgattgac
ttcaccaagaagggatttctcttccgggggcagatctctgagaccctgaagacgcggggc
atctttgagaccaaattcctctctcagatcgagagtgaccgattagcactgctccaggtt
cgggccatcctccagcagctgggactgaacagcacctgtgatgacagtatcctcgtcaag
actgtgtgtggggtcgtgtccaggagagctgcagagctgtgtggcgcagggatggctgct
gtggtagataagatccgtgagaacaggagactggaccatctgaatgtgactgtgggagtg
gacgggacactctacaaacttcatccacacttctccagaatcatgcaccaaaccgtgaag
gaactgtcaccacaatgtaatgtgtccttcctgctgtcagaagatggtagtggcaagggg
gccgccctcatcacggctgtgggtgtgcggctgcgaggagaagtgcccccaaccagctaa

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