KEGG   Lacticaseibacillus casei 12A: LCA12A_2346
Entry
LCA12A_2346       CDS       T03665                                 
Name
(GenBank) DNA ligase
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
lcx  Lacticaseibacillus casei 12A
Pathway
lcx03030  DNA replication
lcx03410  Base excision repair
lcx03420  Nucleotide excision repair
lcx03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:lcx00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    LCA12A_2346
   03410 Base excision repair
    LCA12A_2346
   03420 Nucleotide excision repair
    LCA12A_2346
   03430 Mismatch repair
    LCA12A_2346
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:lcx03032]
    LCA12A_2346
   03400 DNA repair and recombination proteins [BR:lcx03400]
    LCA12A_2346
Enzymes [BR:lcx01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     LCA12A_2346
DNA replication proteins [BR:lcx03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     LCA12A_2346
DNA repair and recombination proteins [BR:lcx03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     LCA12A_2346
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     LCA12A_2346
   MMR (mismatch excision repair)
    DNA ligase
     LCA12A_2346
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      LCA12A_2346
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 DNA_ligase_ZBD PTCB-BRCT HHH_8 HHH HHH_3 zf-NADH-PPase
Other DBs
NCBI-ProteinID: EKQ00389
LinkDB
Position
995260..997284
AA seq 674 aa
MLAKPAAQFTLEEAQAEVEKLRKQLNQWRLEYYTKDAPTVTDNVYDDHYRDLQALEEAYP
KLVTPDSPTQEVGDVINSDFAKVQHPIPMLSMGDVFSFEELSEWDARMQSNVGHPVDYNV
ELKIDGLALSLIYENGKLVQGSTRGDGNVGEDVTRNVLTIASVPKQLKQPLSLEVRGECY
MPKAAFAKLNARQETEGGTPFANPRNAAAGSLRQLDAKVTAARELDTFIYTLIEPERFNV
TTQHEAIAFMQALGFTTNPSSEVAGDMQAIDTYIKKYTTDRDALPYGIDGIVLKVNDLAL
QAQLGNTVKVPRWEIAYKFPPEEAETVIHDIVWTVGRTGVVTPTAVMDPVQLAGTTVARA
TLHNADMIRDKDIRIGDTVMLHKAGDIIPEVSRVLVAKRPADTPPAPIPEVCPSCGQKLV
HLDDEVALRCINPMCPAQVQEQLTHFASRNAMNIDGLGPKIVAQLQAKHLVKDVADLYHL
TAADLAKLDKFKEKSINNLLSAINNSRQNSVERLIFGLGIRHVGGKAARILAEHFGDLDH
LMTASQEAIADVPNIGPTIAEAIVTYFKAATVQKLITQLREADVNLRYTGPTKPVVKDSF
VAGKTVVITGKFAEFSRPALTKQLEGLGAKVTGSVSKKTDLLIAGDAAGSKLAKAQSLNV
PIMNETELLANLKD
NT seq 2025 nt   +upstreamnt  +downstreamnt
gtgttagcaaaaccagctgcacaattcacacttgaagaagctcaggcggaagtcgaaaag
cttcggaagcaactgaatcaatggcgtcttgagtattacaccaaagatgcgccaactgtg
accgataacgtctatgacgatcattatcgcgatttacaggcactcgaggaggcttatccc
aagctagtcacgcctgattcgccaactcaagaagtcggcgatgtcattaattcggacttt
gccaaggtgcaacacccaattccgatgttgtcgatgggcgatgttttttcgttcgaagag
ctgagtgaatgggatgctcgcatgcaaagcaatgtcggccatccggtggattacaatgtt
gagttgaaaatcgacgggttggctttatctctgatttatgaaaacggcaaactcgttcaa
ggctcaacacgtggtgatggtaatgtcggtgaagatgtgaccagaaatgtgttgaccatt
gcgtcagttcccaagcagttaaagcagccactttcactcgaggtacggggtgaatgttat
atgcctaaggcggcgtttgccaagctgaatgcgcggcaggaaactgagggcggcacgcct
tttgccaatccacgtaacgcggcagctggatcactccgacagttagacgccaaagtcacc
gctgctcgagagctggataccttcatttatacgttaattgaaccagagcggtttaacgtg
accacgcagcatgaggcgattgcgtttatgcaggcacttggatttacaacaaatccaagt
tcagaagtggctggtgacatgcaggcgattgacacctacattaagaagtacaccaccgac
cgtgatgcgttgccttacggaattgatgggatcgttttgaaagtgaacgatttggcgctg
caagcgcaactaggcaacaccgttaaagtgccacgctgggaaattgcctacaaattccca
cctgaagaagcagagaccgtcattcatgacattgtctggacagttggtcgaaccggtgtg
gtcacgccgactgccgtgatggaccccgttcagcttgctggaaccacagtggcacgggcc
acgttgcacaacgcggatatgattcgtgataaagatattcgcatcggcgacaccgtcatg
ttgcacaaagcaggcgacattattcctgaagtttcgcgggtactggttgctaaacgtcca
gcggatacgccaccggcgccgattccagaggtctgcccgtcatgtggccaaaaactggtc
catctcgacgatgaagtagctttgcgttgcatcaatccgatgtgtccggcacaggtccaa
gagcagctcacccattttgcgtctcgcaacgcgatgaatatcgatggcttaggcccgaag
attgtggcacagttgcaggccaaacatctggtaaaagatgtcgctgatttgtatcacctc
acagctgcggatctggcgaaattagataagtttaaagaaaaatcaattaataatttgtta
agtgcgatcaacaacagtcggcaaaactcggtagaacgcctaatctttgggttgggcatt
cggcacgttggcggtaaagctgcccgaattctggccgagcatttcggcgatttggatcat
ctgatgaccgccagtcaagaggcgatcgcagacgtgccaaatatcgggccgaccattgcg
gaagcgatcgtgacgtattttaaagccgcaacggttcaaaagttgatcacgcagttgcgc
gaagctgatgttaacctgcgttacaccggaccgaccaaaccagtggtcaaagatagtttt
gttgcaggaaaaaccgtcgtgattaccggtaagtttgccgagttttcgcggccagcactc
acgaagcagctagaaggattaggagccaaggtcacaggttcagtttcaaagaaaacggac
ctcctgatcgctggcgacgcggctggcagtaagttggcaaaggcacaaagcttgaatgtc
ccaatcatgaatgagacggaattgctggcgaatttgaaggattga

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