Lactobacillus johnsonii NCC 533: LJ_0269
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Entry
LJ_0269 CDS
T00158
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ljo
Lactobacillus johnsonii NCC 533
Pathway
ljo00300
Lysine biosynthesis
ljo00550
Peptidoglycan biosynthesis
ljo01100
Metabolic pathways
ljo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ljo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LJ_0269
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LJ_0269
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LJ_0269
Enzymes [BR:
ljo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LJ_0269
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AAS08252
UniProt:
Q74LB5
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All DBs
Position
302159..303526
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AA seq
455 aa
AA seq
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MKMQLAEIAKALNSSVNMGEDKVITSVVFDSRKATPNSLFIPLDGARDGHDFVSNAMANG
AEATLWKKGHEGMPTDVPVIEVEDPLTALQNLAKYYLGKVNPTVVGITGSNGKTTTKDMV
AAVLSKRFNVHKTQANFNNEIGVPVTILEMKPSTEILVLEMGMDRPGQLHHLSELVRPDV
CVITMIGEAHIEFFGTRDKIADAKMEITDFLKEDGKFIYNGDEPLLEERAAKIKQEKSTF
GFREEDTVFATTFRSYMHHATFEVNGSTQQFKIPMIGKHNVSNALAAISVGRHFGENDEQ
IAQALANFTPTANRMQWKKGDVGEAIMDDVYNSNPIAVKAVTTSFGQVMVEDGGRRIAVL
GDMLELGDESADLHASLAASLDPAIINELYLYGPEMKNLYDALVDKYPAENLHYYPQDQM
NHMIDDLKNDIKPADIVMLKGSHGMHLEKVLDRLM
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgcaacttgctgagatcgctaaagcattaaatagttcagttaatatgggagaa
gacaaggtcattacatctgttgtttttgactcaagaaaagcaactcccaattctttgttt
attcccttagatggtgcaagggatggacatgattttgtatctaatgcaatggcaaacgga
gcagaagcaaccctttggaaaaaaggacatgagggtatgcctactgatgtgccagttatt
gaagtggaagatccgctaactgcgcttcaaaatttagctaaatattacttaggtaaagtt
aatccaactgttgttggtattactgggtctaacggtaagactacaactaaggatatggtt
gcagctgttttatcaaaaagatttaacgtgcataagacacaggctaactttaataacgaa
attggggtacctgtaactattttagagatgaaaccatctactgaaattttagttcttgaa
atggggatggatcgtccgggacaattacaccatttaagtgaattagtaagaccagatgtt
tgtgtcattacaatgattggtgaagctcatattgagttcttcggtactagagataagatt
gcagacgctaaaatggaaattactgacttcctaaaggaagatggtaagtttatttacaat
ggcgatgaacctttactagaagagcgtgcagctaagattaagcaagaaaagagtactttt
ggttttagagaagaagatactgtttttgcgactacatttagatcttacatgcaccatgct
acttttgaagtaaatgggtcaacacagcaatttaaaattccaatgattggaaaacataac
gtctcgaatgctcttgcagccattagtgtaggccgccattttggtgaaaatgatgaacaa
attgcccaagctttagctaacttcaccccaacagcaaatagaatgcaatggaagaagggt
gatgtaggcgaagcaattatggatgatgtttacaactcaaatccaattgcggttaaggct
gttacgacttcgtttggacaagtaatggtcgaagatggtgggcgcagaattgctgtctta
ggtgatatgttagagcttggagatgaatcagctgatcttcatgcgtctcttgcagctagc
ttggatccagcaattattaatgaactatatttatatggtccagagatgaaaaacttatat
gatgctcttgttgataagtacccagcagaaaacttgcactattatccacaagatcaaatg
aatcatatgattgatgacttaaagaatgatattaagccagctgatattgtaatgctaaag
ggatcacatgggatgcatttggaaaaggttttagaccgtctcatgtag
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