KEGG   Macaca mulatta (rhesus monkey): 710798Help
Entry
710798            CDS       T01028                                 

Gene name
PKM, PKM2
Definition
pyruvate kinase, muscle
Orthology
K00873  
pyruvate kinase [EC:2.7.1.40]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
Glycolysis / Gluconeogenesis
Purine metabolism
Pyruvate metabolism
Metabolic pathways
Carbon metabolism
Biosynthesis of amino acids
Type II diabetes mellitus
Viral carcinogenesis
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Glycolysis, core module involving three-carbon compounds
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
Guanine ribonucleotide biosynthesis IMP => GDP,GTP
Class
Metabolism; Overview; Carbon metabolism [PATH:mcc01200]
Metabolism; Overview; Biosynthesis of amino acids [PATH:mcc01230]
Metabolism; Carbohydrate metabolism; Glycolysis / Gluconeogenesis [PATH:mcc00010]
Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:mcc00620]
Metabolism; Nucleotide metabolism; Purine metabolism [PATH:mcc00230]
Human Diseases; Cancers; Viral carcinogenesis [PATH:mcc05203]
Human Diseases; Endocrine and metabolic diseases; Type II diabetes mellitus [PATH:mcc04930]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
LinkDB All DBs
Position
13
AA seq 531 aa AA seqDB search
MSKPHSEAGTAVIQTQQLHAAMADTFLEHMCRLDIDSPPATARNTGIICTIGPASRSVET
LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATEGFASDPILYRPVAVALDTKGPEIR
TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
ISLQVKQKGADFLVTEVENGGSSGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
LASFILKAADVHEVRKVLGEKGNDIKIISKIENHEGVRRFDEILEASDGIMVARGDVGIE
IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAILDGADCIM
LSGETAKGDYPLETVRMQHLIAREAEAAIYHLQLFEELHRLAPITSDPTEATTVGAVEAS
FKCCSGAIIVPTKSGRSAHQVARYCPRAPIIAGTRNPQTARQAHLYCGIFPVLCKDPVQE
AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGCRPGSGFTNTMRVVPVP
NT seq 1596 nt NT seq  +upstreamnt  +downstreamnt
atgtcgaagccccatagtgaagccgggactgccgtcattcagacccagcagctgcacgca
gccatggctgacacattcctggagcacatgtgccgcctggacattgactcaccacccgcc
acagcccggaacactggcatcatctgtaccattggcccagcttcccgatcagtggagacg
ttgaaggagatgattaagtctggaatgaatgtggctcgtctgaacttctctcatggaact
catgagtaccacgcggagaccatcaagaatgtgcgcacagccacggaaggctttgcttct
gaccccatcctctaccggcccgttgctgtggctctggacactaaaggacctgagatccga
actgggctcatcaagggcagcggcactgcagaggtggagctgaagaagggagccactctc
aaaatcacgctggataacgcctacatggaaaagtgtgacgagaacatcctgtggctggac
tacaagaacatctgcaaagtggtggaagtgggcagcaagatctacgtggatgatggactt
atttctcttcaggtgaagcagaaaggtgctgacttcctggtgacggaggtggaaaatggt
ggctcctcgggcagcaagaagggtgtaaaccttcctggggctgctgtggacttgcctgct
gtgtcggaaaaggacatccaggatctgaagtttggggtcgagcaggatgttgatatggtg
cttgcgtcattcatcctcaaggcagctgatgtccatgaagttaggaaggtcctgggagag
aagggaaacgacatcaagataatcagcaaaatcgagaatcatgagggggttcggaggttt
gatgaaatcctggaggccagtgatgggatcatggtggctcgtggtgatgtaggcattgag
attcctgcggagaaggtcttccttgctcagaagatgatgattgggcggtgcaaccgagct
gggaagcctgtcatctgtgctactcagatgctggagagcatgatcaagaagccccgcccc
acccgggctgaaggcagtgatgtggccaatgcaattctggatggagccgactgcatcatg
ctgtctggagaaacagccaaaggggactatcctctggagactgtgcgcatgcagcacctg
atagcccgtgaagcagaggccgccatctaccacttgcaattatttgaggaactccaccgc
ctggcgcccattaccagcgaccccacagaagccaccaccgtgggtgccgtggaggcctcc
ttcaagtgctgcagtggggccataatcgtccccaccaagtctggcaggtctgctcatcag
gtggccagatactgcccacgtgcccccatcattgctgggacccggaatccccagacagct
cgtcaggcccacctgtactgtggcatcttccctgtgctgtgcaaggacccagtccaggag
gcctgggctgaggacgtggacctccgggtgaactttgccatgaatgttggcaaggcccga
ggcttcttcaagaagggagatgtggtcattgtgctgaccggatgtcgccctggctccggc
ttcaccaacaccatgcgtgttgttcctgtgccgtga

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