KEGG T01028: 710798

Macaca mulatta (rhesus monkey): 710798

Entry

710798 CDS T01028

Gene name

PKM, PKM2

Definition

pyruvate kinase, muscle

Orthology

K00873

pyruvate kinase [EC:2.7.1.40]

Organism

mcc Macaca mulatta (rhesus monkey)

Pathway

mcc00010	Glycolysis / Gluconeogenesis
mcc00230	Purine metabolism
mcc00620	Pyruvate metabolism
mcc01100	Metabolic pathways
mcc01230	Biosynthesis of amino acids
mcc04930	Type II diabetes mellitus
mcc05203	Viral carcinogenesis

Module

mcc_M00001	Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mcc_M00002	Glycolysis, core module involving three-carbon compounds
mcc_M00049	Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
mcc_M00050	Guanine ribonucleotide biosynthesis IMP => GDP,GTP

Class

Metabolism; Carbohydrate metabolism; Glycolysis / Gluconeogenesis [PATH:mcc00010]
Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:mcc00620]
Metabolism; Nucleotide metabolism; Purine metabolism [PATH:mcc00230]
Human Diseases; Cancers; Viral carcinogenesis [PATH:mcc05203]
Human Diseases; Endocrine and metabolic diseases; Type II diabetes mellitus [PATH:mcc04930]

SSDB

Motif

Pfam:

PK PK_C HpcH_HpaI IMPDH

Other DBs

NCBI-GI:

297266829

NCBI-GeneID:

710798

Position

AA seq 531 aa
MSKPHSEAGTAVIQTQQLHAAMADTFLEHMCRLDIDSPPATARNTGIICTIGPASRSVET
LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATEGFASDPILYRPVAVALDTKGPEIR
TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
ISLQVKQKGADFLVTEVENGGSSGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
LASFILKAADVHEVRKVLGEKGNDIKIISKIENHEGVRRFDEILEASDGIMVARGDVGIE
IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAILDGADCIM
LSGETAKGDYPLETVRMQHLIAREAEAAIYHLQLFEELHRLAPITSDPTEATTVGAVEAS
FKCCSGAIIVPTKSGRSAHQVARYCPRAPIIAGTRNPQTARQAHLYCGIFPVLCKDPVQE
AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGCRPGSGFTNTMRVVPVP

NT seq 1596 nt +upstreamnt +downstreamnt
atgtcgaagccccatagtgaagccgggactgccgtcattcagacccagcagctgcacgca
gccatggctgacacattcctggagcacatgtgccgcctggacattgactcaccacccgcc
acagcccggaacactggcatcatctgtaccattggcccagcttcccgatcagtggagacg
ttgaaggagatgattaagtctggaatgaatgtggctcgtctgaacttctctcatggaact
catgagtaccacgcggagaccatcaagaatgtgcgcacagccacggaaggctttgcttct
gaccccatcctctaccggcccgttgctgtggctctggacactaaaggacctgagatccga
actgggctcatcaagggcagcggcactgcagaggtggagctgaagaagggagccactctc
aaaatcacgctggataacgcctacatggaaaagtgtgacgagaacatcctgtggctggac
tacaagaacatctgcaaagtggtggaagtgggcagcaagatctacgtggatgatggactt
atttctcttcaggtgaagcagaaaggtgctgacttcctggtgacggaggtggaaaatggt
ggctcctcgggcagcaagaagggtgtaaaccttcctggggctgctgtggacttgcctgct
gtgtcggaaaaggacatccaggatctgaagtttggggtcgagcaggatgttgatatggtg
cttgcgtcattcatcctcaaggcagctgatgtccatgaagttaggaaggtcctgggagag
aagggaaacgacatcaagataatcagcaaaatcgagaatcatgagggggttcggaggttt
gatgaaatcctggaggccagtgatgggatcatggtggctcgtggtgatgtaggcattgag
attcctgcggagaaggtcttccttgctcagaagatgatgattgggcggtgcaaccgagct
gggaagcctgtcatctgtgctactcagatgctggagagcatgatcaagaagccccgcccc
acccgggctgaaggcagtgatgtggccaatgcaattctggatggagccgactgcatcatg
ctgtctggagaaacagccaaaggggactatcctctggagactgtgcgcatgcagcacctg
atagcccgtgaagcagaggccgccatctaccacttgcaattatttgaggaactccaccgc
ctggcgcccattaccagcgaccccacagaagccaccaccgtgggtgccgtggaggcctcc
ttcaagtgctgcagtggggccataatcgtccccaccaagtctggcaggtctgctcatcag
gtggccagatactgcccacgtgcccccatcattgctgggacccggaatccccagacagct
cgtcaggcccacctgtactgtggcatcttccctgtgctgtgcaaggacccagtccaggag
gcctgggctgaggacgtggacctccgggtgaactttgccatgaatgttggcaaggcccga
ggcttcttcaagaagggagatgtggtcattgtgctgaccggatgtcgccctggctccggc
ttcaccaacaccatgcgtgttgttcctgtgccgtga

All links

Pathway (11)   
   KEGG PATHWAY (7)   
   KEGG MODULE (4)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   UniGene (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (4)   
   Pfam (4)   
All databases (43)   

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