Mycolicibacterium gilvum PYR-GCK: Mflv_0065
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Entry
Mflv_0065 CDS
T00498
Name
(GenBank) uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mgi
Mycolicibacterium gilvum PYR-GCK
Pathway
mgi00860
Porphyrin metabolism
mgi01100
Metabolic pathways
mgi01110
Biosynthesis of secondary metabolites
mgi01120
Microbial metabolism in diverse environments
mgi01240
Biosynthesis of cofactors
Module
mgi_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mgi_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mgi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Mflv_0065
Enzymes [BR:
mgi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Mflv_0065
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Mflv_0065
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ABP42561
UniProt:
A4T339
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All DBs
Position
complement(57366..59075)
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AA seq
569 aa
AA seq
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MSLRGRKNKPGRITFVGSGPGDPGLLTSRARAVLANAALVFTDPDVPEAVRALVGSELPP
PSGPLPPVADAAPKTAAAGADQPASQDAAPADAAKTAKAAEDAVIPGGPDVRPALGDPAE
VAKTLAHEARTGVDVVRLVAGDPLSNDSVITEVNALAKTQLSFEIVPGLPGTSAVPTYAG
LPLGSSHTVADVRGDVDWAALAAAPGPLILHATPSHLPEAARTLIEYGLAESTPAVVTAN
GTTCQQRSVETTLAGLLDKAALAGTEPAGPLTGTLVVTIGRTVANRAKLNWWESRALYGW
TVLVPRTKDQAGEMSDRLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFT
STNAVRAVWEKFNEFGLDARAFSGVKIACVGQATAEKVRAFGINPELVPTGEQSSLGLLD
EFPPYDDIFDPVNRVLLPRADIATETLAEGLRELGWEIEDVTAYRTVRAAPPPAHTREMI
KTGGFDAVCFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPEVAAVG
PLVEALAEHAARLRAEGALPPPRKKSRRR
NT seq
1710 nt
NT seq
+upstream
nt +downstream
nt
atgagcttgcgaggacgcaagaacaagcccggccgcatcacgttcgtcggctccggaccc
ggtgatccgggtctgttgacgtcacgtgcccgcgctgtgctggccaacgccgccctggtg
ttcaccgatcccgacgtgcctgaggcagtgcgcgccctggtgggctccgagctgccgccg
ccgtcggggccgttgcccccggtggccgacgcggcgcccaagaccgccgctgccggcgcc
gatcagccggcgagccaggacgccgccccggccgacgccgcgaagaccgccaaagccgcc
gaggatgcggtgatcccgggtggccccgatgtgcggcccgcgctcggtgatccggccgag
gtcgccaagacgctggcccacgaggctcgtacgggtgtcgacgtggtccggctcgtcgcc
ggggatccgctgtcgaacgactcggtgatcaccgaggtgaacgcgctggccaagacccag
ctgagcttcgagatcgtgcccggactgcccggtacctcggctgtgccgacgtatgccggt
ctgccgctgggctcctcgcacaccgtcgccgacgtgcgcggggatgtcgactgggcggcg
ctggccgccgcgccgggaccgctgatcctgcacgcgaccccgtcgcaccttcccgaggcg
gcgcgcacgctgatcgagtacggcctcgccgagtccacccccgcggtggtcaccgccaac
ggcaccacgtgccaacagcgttcggtcgagaccacgctcgccggtctgctcgacaaggcc
gcgctggccggtaccgagcccgccgggccgctgacggggacgctggtcgtcaccatcggt
cgcaccgtcgccaaccgcgcgaagctgaactggtgggagagccgtgcgctgtacggctgg
accgtcctcgtgccgcgcaccaaggaccaggccggtgagatgagcgatcgtctcgtagga
cacggcgcgctgccgatcgaggtgccgaccatcgccgtcgagccgccgcgcagccccgcc
cagatggaaagggccgtcaagggtttggtggacggccgattccagtgggtggtgttcacc
tccaccaacgccgtgcgtgcggtgtgggagaagttcaacgagttcggcctcgacgcccgc
gcgttctccggtgtgaagatcgcctgcgtcggacaggcgaccgctgagaaggtgcgcgcg
ttcgggatcaacccggagctggtgcccaccggcgagcagtcgtccctcggcctgctcgac
gaattcccgccgtacgacgacatcttcgatccggtcaaccgggtgctgttgccgcgtgcc
gacatcgccaccgagacgctggccgaaggtctgcgcgaactcggttgggagatcgaggat
gtcaccgcgtaccgcaccgtccgcgcggctccgccgccggcgcacacccgcgagatgatc
aagacgggcggcttcgacgccgtgtgcttcacgtcgagctcgacggtgcgcaacctggtc
ggcatcgccggcaagccgcacgcccgcacgatcgtcgcgtgcatcggacccaagactgcc
gaaaccgcagcggaattcgggctgcgcgtcgacgtccagcccgaggtggccgcggtcgga
ccgctggtcgaggcgctggccgaacacgctgcccggctgcgcgccgagggtgcgttgccg
ccgccgcggaagaagagtcgccgccgctag
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