Mus musculus (house mouse): 56489
Help
Entry
56489 CDS
T01002
Symbol
Ikbke, IKK-E, IKK-i, IKKepsilon, Ikki
Name
(RefSeq) inhibitor of kappaB kinase epsilon
KO
K07211
inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:
2.7.11.10
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04620
Toll-like receptor signaling pathway
mmu04621
NOD-like receptor signaling pathway
mmu04622
RIG-I-like receptor signaling pathway
mmu04623
Cytosolic DNA-sensing pathway
mmu04625
C-type lectin receptor signaling pathway
mmu04657
IL-17 signaling pathway
mmu04936
Alcoholic liver disease
mmu05160
Hepatitis C
mmu05161
Hepatitis B
mmu05162
Measles
mmu05164
Influenza A
mmu05165
Human papillomavirus infection
mmu05167
Kaposi sarcoma-associated herpesvirus infection
mmu05168
Herpes simplex virus 1 infection
mmu05169
Epstein-Barr virus infection
mmu05171
Coronavirus disease - COVID-19
mmu05207
Chemical carcinogenesis - receptor activation
mmu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
56489 (Ikbke)
04621 NOD-like receptor signaling pathway
56489 (Ikbke)
04622 RIG-I-like receptor signaling pathway
56489 (Ikbke)
04623 Cytosolic DNA-sensing pathway
56489 (Ikbke)
04625 C-type lectin receptor signaling pathway
56489 (Ikbke)
04657 IL-17 signaling pathway
56489 (Ikbke)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
56489 (Ikbke)
09172 Infectious disease: viral
05161 Hepatitis B
56489 (Ikbke)
05160 Hepatitis C
56489 (Ikbke)
05171 Coronavirus disease - COVID-19
56489 (Ikbke)
05164 Influenza A
56489 (Ikbke)
05162 Measles
56489 (Ikbke)
05168 Herpes simplex virus 1 infection
56489 (Ikbke)
05167 Kaposi sarcoma-associated herpesvirus infection
56489 (Ikbke)
05169 Epstein-Barr virus infection
56489 (Ikbke)
05165 Human papillomavirus infection
56489 (Ikbke)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
56489 (Ikbke)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
56489 (Ikbke)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
56489 (Ikbke)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
56489 (Ikbke)
Protein kinases [BR:
mmu01001
]
Serine/threonine kinases: Other
IKK family [OT]
56489 (Ikbke)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
RH_dom
Motif
Other DBs
NCBI-GeneID:
56489
NCBI-ProteinID:
NP_062751
MGI:
1929612
Ensembl:
ENSMUSG00000042349
UniProt:
Q9R0T8
LinkDB
All DBs
Position
1:complement(131182337..131207339)
Genome browser
AA seq
717 aa
AA seq
DB search
MQSTTNYLWHTDDLLGQGATASVYKARNKKSGEVVAVKVFNSASYRRPPEVQVREFEVLR
RLNHQNIVKLFAVEETGGSRQKVLIMEYCSSGSLLSVLEDPENTFGLSEEEFLVVLRCVV
AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLSDFGAARKLDDDEKFVSVYGTEEYL
HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTE
KPAGAISGTQKQENGPLEWSYSLPITCRLSMGLQNQLVPILANILEVEEDKCWGFDQFFA
ETSDILQRTVIHVFSLPQAVLHHVYIHAHNTIAIFLEAVYEQTNVTPKHQEYLFEGHPCV
LEPSLSAQHIAHTAASSPLTLFSMSSDTPKGLAFRDPALDVPKFVPKVDLQADYSTAKGV
LGAGYQALWLARVLLDGQALMLRGLHWVLEVLQDTCQQTLEVTRTALLYLSSSLGTERFS
SGAGMPDVQERKEATELRTRLQTLSEILSKCSHNVTETQRSLSCLGEELLKNRDQIHEDN
KSIQKIQCCLDKMHFIYKQFKKSRMRPGLSYNEEQIHKLDKVNFSHLAKRLLQVFQEECV
QTYQVSLVTHGKRMRQVQRAQNHLHLIGHSVATCNSEARGAQESLNKIFDQLLLDRASEQ
GAEVSPQPMAPHPGPDPKDLVFHMQELCNDMKLLAFDLQDNNRLIERLHRVPSAPDV
NT seq
2154 nt
NT seq
+upstream
nt +downstream
nt
atgcagagtaccactaactacctgtggcatactgatgacctgctagggcagggggccact
gccagtgtgtacaaggcccgaaacaagaaatccggggaggtggttgctgtaaaggtcttc
aactcagccagctatcggcgacctcctgaggttcaggtgagggagtttgaggtcctgcgg
aggctgaatcaccagaacatcgtgaagctattcgcagtggaggaaacgggaggcagccgg
cagaaggtgctaatcatggagtactgctccagtgggagcctgctgagcgtgctggaagac
cctgagaacacgttcgggctttctgaagaggagttcctagtggtgctgcgctgtgtggtg
gctggcatgaaccacctgcgggagaatggcattgtccatcgggacatcaaacctgggaac
atcatgcgcctggtgggcgaggaggggcagagcatctataagctgtctgacttcggggct
gcccgcaagctggacgatgatgagaagtttgtttctgtctatggtacagaggaatacctg
caccctgacatgtatgagcgtgcagtgctgcgcaaaccccagcaaaaggcatttggtgtg
actgtggatctctggagtattggggtgaccctgtaccacgcagccacaggcagtctgccc
ttcatccccttcggtgggccccggcgcaacaaagagatcatgtacagaatcaccacagag
aagccagccggggccatttcagggactcagaagcaggaaaatggtcccttggagtggagc
tacagcctccccatcacctgtagactgtccatgggactgcagaaccagctggtgcccatc
ctggccaacatcctggaggtggaagaggataagtgctggggctttgatcagttcttcgcg
gagaccagtgacattctgcagcgaacggtcatccacgtcttttccctaccccaggccgtt
ttgcatcatgtctacatccacgcccacaacacgattgccatctttttggaggctgtatat
gagcagaccaacgtgacccccaaacaccaggagtacctcttcgagggtcacccttgtgtc
cttgagccaagcctctcagcccagcacatcgcccacacagctgccagcagccctctaact
ctgttcagcatgtccagcgacacacctaaggggctggccttcagggaccctgctctggat
gtcccaaagttcgtccctaaggttgacctacaggccgattacagcacagctaagggggtg
ctgggcgctggctaccaggccctgtggctggcgcgggtcctgctggatggacaggcgttg
atgcttcgggggttacattgggtcctggaggtgcttcaggacacgtgccagcagacactg
gaggtcacacggacagccctcctctacctcagcagcagcctgggcactgaaaggttcagc
agtggagcggggatgcctgacgtccaggaacgaaaggaggccacagagctaagaaccagg
ctgcagactctctcagagatcctgtctaaatgttcccacaatgtcacagaaacccaaagg
agcctgagctgtctgggtgaagagcttttaaagaaccgggaccagattcatgaggataac
aaaagtatccagaagattcagtgttgtttggacaagatgcacttcatctacaaacagttc
aagaaatccaggatgaggccagggctcagctacaatgaggagcagatccacaagctggat
aaggtaaatttcagtcatctagccaagaggctgctgcaggtgttccaggaggagtgtgtg
cagacgtatcaggtgtcgctggtcacacacggcaagcggatgaggcaggtgcagagggcc
cagaaccacctgcatctcattggccactctgtggccacctgtaactcggaagcccgggga
gcccaggagagtctgaacaagatctttgatcagctccttctggacagagcttccgaacag
ggagctgaggtgtcaccgcaacctatggctcctcatcccggccctgatccgaaggacctg
gtcttccacatgcaggagctttgtaatgatatgaagctattggcctttgatctccaggac
aacaaccgactcatcgaacggttacatagagttccatcggcaccagatgtctga
DBGET
integrated database retrieval system
