Mus musculus (house mouse): 69719
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Entry
69719 CDS
T01002
Symbol
Cad, 2410008J01Rik, Cpad
Name
(RefSeq) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
KO
K11540
carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:
6.3.5.5
2.1.3.2
3.5.2.3
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00240
Pyrimidine metabolism
mmu00250
Alanine, aspartate and glutamate metabolism
mmu01100
Metabolic pathways
mmu01240
Biosynthesis of cofactors
Module
mmu_M00051
De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
69719 (Cad)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
69719 (Cad)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mmu01002
]
69719 (Cad)
Enzymes [BR:
mmu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.2 aspartate carbamoyltransferase
69719 (Cad)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.2 In cyclic amides
3.5.2.3 dihydroorotase
69719 (Cad)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
69719 (Cad)
Peptidases and inhibitors [BR:
mmu01002
]
Cysteine peptidases
Family C26: gamma-glutamyl hydrolase family
69719 (Cad)
Metallo peptidases
Family M38: beta-aspartyl dipeptidase family
69719 (Cad)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CPSase_L_D2
GATase
CPSase_sm_chain
OTCace_N
OTCace
CPSase_L_D3
ATP-grasp
MGS
Dala_Dala_lig_C
ATPgrasp_Ter
Amidohydro_1
ATP-grasp_3
GARS_A
Peptidase_C26
Motif
Other DBs
NCBI-GeneID:
69719
NCBI-ProteinID:
NP_076014
MGI:
1916969
Ensembl:
ENSMUSG00000013629
UniProt:
B2RQC6
LinkDB
All DBs
Position
5:31211964..31235823
Genome browser
AA seq
2225 aa
AA seq
DB search
MAALVLEDGSVLQGRPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
GIPSDEEDEFGLSKWFESSEIHVAGLVVGECCPTPSHWSANCTLHEWLQQRGIPGLQGVD
TRELTKKLREQGSLLGKLVQKGTEPSALPFVDPNARPLAPEVSIKTPRVFNAGGAPRICA
LDCGLKYNQIRCLCQLGAEVTVVPWDHELDSQKYDGLFLSNGPGDPASYPGVVSTLSRVL
SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGTGRCFLTSQNHGFAVD
ADSLPAGWAPLFTNANDCSNEGIVHDSLPFFSVQFHPEHRAGPSDMELLFDVFLETVREA
AAGNIGGQTVRERLAQRLCPPELPIPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITLHYVTQVIRNERPDGVLLTFGGQT
ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQ
AQAAAERLGYPVLVRAAFALGGLGSGFASTKEELSALVAPAFAHTSQVLIDKSLKGWKEI
EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRRTAIKVTQHLG
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN
SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL
RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVERLYELTRIDCWFLHRM
KRIVTHAQLLEQHRGQALPQDLLHQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAV
KQIDTVAAEWPAQTNYLYLTYWGNTHDLDFRAPHVLVLGSGVYRIGSSVEFDWCAVGCIQ
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP
NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCHT
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV
ACDGIVSAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGQELQVTGPFN
LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRIIMGEKVEPVGLMTGSGVVG
VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPEKNILLTIG
SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI
LDQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL
GQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGVTMV
CAMPNTRPPIIDAPALALAQKLAEAGARCDFTLFLGASSENAGTLGAVAGSAAGLKLYLN
ETFSELRLDSVAQWMEHFETWPAHLPIVAHAERQSVAAVLMVAQLTQRPVHICHVARKEE
ILLIKTAKAQGLPVTCEVAPHHLFLNREDLERLGPGKGEVRPELGSREDMEALWENMAVI
DCFASDHAPHTLEEKCGPKPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIF
HLPLQEDTYVEVDLEHEWTVPSHMPFSKARWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL
VPPGYGQDVRKWPQGVVPQPPPSTPATTEITTTPERPRRVIPGLPDGRFHLPPRIHRASD
PGLPAEEPKEKPPRKVVEPELMGTPDGPCYPAPPVPRQASPQNLGSSGLLHPQMSPLLHS
LVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSF
AAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVIVLRHPQPGAVELAAKHCRR
PVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS
LRYVAPPSLRMPPSVRDFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSVQEYEA
CFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLAT
VLGRF
NT seq
6678 nt
NT seq
+upstream
nt +downstream
nt
atggcggccctggtgttggaggacgggtcggtgctgcagggccggccctttggggccgct
gtgtcgactgctggggaagtggtgtttcagaccggcatggtcggctacccagaggccctc
actgacccttcctacaaagctcagatcctagtgctaacgtatcctctcatcggcaactac
ggcattccctcagatgaagaggacgagttcggcctgagcaagtggtttgaatcctcggag
atccacgtggcgggacttgtagtgggagaatgctgtcccacacccagccactggagtgcc
aactgcaccctgcatgagtggctgcaacagcgtggcatccccggcctgcaaggagtggac
actcgggagctgactaagaagttgcgggagcaagggtctcttttggggaagctggtccag
aaagggacagagccgtcagccctgccattcgtggaccccaatgccaggcccctggcacca
gaggtctctattaagactccacgggtattcaatgcagggggtgcccctcggatctgtgct
ctggattgtggcctcaagtataatcagatccgatgtctctgccagcttggggctgaagtt
accgtggtaccctgggaccacgagttagacagtcagaaatatgacggtctcttcctaagt
aatggacccggtgaccctgcctcttacccgggtgtggtgtccacactgagccgagtcttg
tctgaacctaacccccgacctgtgtttggaatctgccttggacaccagctgttggcttta
gccatcggggccaaaacttacaagatgagatacggaaaccgaggccacaaccagccctgt
ttactggtgggcactgggcgctgctttctgacgtcccagaatcatgggtttgcagtggac
gcagattcgctgccagcaggctgggctcctctgttcaccaatgccaatgactgttccaat
gaaggcatagtgcacgacagcctgcccttcttcagtgtccagtttcacccagagcaccgg
gccggcccttcagatatggaactgctcttcgatgtatttctagaaactgtgagagaggct
gcagctgggaacattgggggccagacagtaagagaacgcttggctcagcgcctctgtccc
cctgagctccccattcctggttctgggctcccgcctccacgaaaggttctaatcctaggc
tcagggggcctctccattggccaagctggagaatttgactactcgggctctcaggcaatt
aaagccctaaaggaggaaaacatccagacattactaatcaaccccaacattgccacagtg
cagacttctcaggggctggcagacaaggtctatttccttcccataacacttcactacgta
acccaggtaattcgtaatgaacgcccagatggtgtgttactgacttttgggggtcaaaca
gccctgaactgcggtgtggagctgaccaaagctggggtactggctcgatatggggtccgg
gtcttgggtacacccgtggagaccattgaactgactgaggaccgacgagccttcgctgcc
aggatggctgagatcggagagcatgtcgcccccagtgaagcggcaaattctcttgaacag
gctcaggcagctgccgagcgactaggctaccctgtgctggtgcgagcagcctttgccctg
ggtggtctcggttctggctttgcttccaccaaagaggaactctcagctcttgtggctcca
gcttttgcccataccagtcaggtgctgatagacaagtctctgaagggctggaaggagatt
gaatatgaggtggtgagagacgcctatggcaactgcgtaacggtatgcaacatggagaac
ttagacccactgggcattcatactggtgaatccatagtggtggctccgagccagacactg
aatgacagagagtaccagcttctgcgacggacagctatcaaggtcactcagcacctgggc
attgtcggggagtgcaatgtacagtatgctttgaaccccgagtctgagcagtattacatc
attgaagtgaatgccaggctctcccgaagctctgccctggccagtaaggccacaggctat
ccactagcctatgtggcagccaagctagcattgggcattcccctgccagagctcagaaac
tctgttacgggaggaacagcagcctttgagcccagcctggactactgcgtggtaaagatt
cctcgctgggacctcagcaagttcctacgtgtcagtacgaagattgggagttgcatgaag
agtgttggcgaggtcatgggcatcgggcggtcctttgaggaggccttccaaaaggccctg
cgcatggtcgatgagaactgcgtaggcttcgaccatacagtaaagccagtcagcgacatg
gagctggagactccgacggataagcggatctttgtggtggctgccgctctgtgggctggc
tactctgtggagcgcctctacgagctcacccgcattgattgctggttcctgcaccggatg
aagcgcattgtgacccacgcccagttgctggaacaacaccgtggacaagctttaccccaa
gacctgctgcaccaggccaagtgcctcggcttctcagacaagcagattgccctggcagtc
ctgagcacagagctggctgttcggaagctgcgtcaggaactggggatctgcccagcggtg
aaacagattgacacagttgcagctgagtggccagcccagacaaattacctgtacctgaca
tactggggcaacacccatgacctcgactttcgggcacctcacgtcctggtccttggctct
ggtgtctaccggattggctccagtgttgagtttgattggtgtgctgtgggttgcatccag
cagctccggaagatgggttataagaccatcatggtgaactacaacccagagacagtcagc
accgactatgatatgtgtgaccgactctactttgatgagatctcttttgaggtggtgatg
gacatctatgagttagagaaccccgaaggtgtgatcctgtccatgggtgggcagctgccc
aacaacatggccatggctttgcatcggcagcagtgccgagtgctgggcacctcccccgaa
gccatcgactcagccgagaaccgattcaagttctcccggctcctagataccatcggtatc
agccagcctcagtggcgagagctcagtgaccttgagtctgctcgccagttctgccacacg
gtcgggtacccctgcgtagtgcgcccctcctatgtgctcagcggtgctgctatgaatgtg
gcgtacaccgacggggacctggagcgtttcctgagcagtgcggccgccgtctctaaggag
caccccgtagtcatctccaagttcattcaggaagcaaaggagatcgacgtggacgcggtg
gcctgtgacggcatcgtgtcggccattgccatctctgagcacgtggagaatgcaggtgtg
cattcaggtgatgccacgctggtgacccccccacaagacatcaccccgaaaactctggag
cggatcaaagccattgtgcatgctgtgggccaggagctacaggttacaggacccttcaat
ctgcagctcattgccaaggatgaccagctgaaggttattgaatgcaacgtgcgtgtatct
cgctctttccccttcgtgtccaagacactgggtgttgatctagtagccttggccacaagg
atcatcatgggggagaaagtagagcccgtggggctcatgactggctctggagtcgtggga
gtaaaggtacctcagttctccttctcacgcttggccggtgccgacgtggtacttggtgtg
gagatgaccagtactggagaggtggccggcttcggagagagccgttgtgaagcctacctc
aaagccatgctcagcactggctttaagatcccagagaagaacatcctgctgactattggc
agctacaagaacaaaagtgagctgctcccaactgtgcggttgctggagagcctgggctac
agcctctatgccagcctgggtacggcagacttctacactgagcacggggtcaaggtaaca
gctgtggactggcactttgaagaggcggtggatggtgagtgcccaccacaacggagcatc
ttggatcagctggctgaaaatcactttgagctagtgattaacctgtccatgcgtggggct
gggggtcggcgtctttcctccttcgttaccaagggctaccgtacccggcgtctggccgct
gatttctctgtgcctctcatcattgacatcaagtgcaccaaactctttgtggaggcccta
ggccagatcggcccagcccctcctttgaaagtgcacgttgactgcatgacctcccagaag
ctagtgcgcctgcccggattgattgatgtccacgtgcaccttcgggaaccaggtgggaca
cacaaagaggactttgcctcaggcacagctgctgccttggctgggggtgtcaccatggtt
tgtgctatgcctaatacccgaccccccatcattgatgctcctgctctcgcccttgcccag
aagctggcagaggctggcgcccgctgtgactttaccttattccttggagcctcatctgag
aacgcggggactctgggtgctgtggccggctctgcagcaggcctgaagctctacctcaac
gagaccttctctgagctgcggctggacagtgtggcccagtggatggagcattttgaaacc
tggcctgcccacctccccattgtggcccatgcagagcggcagagtgtcgctgcggtcctc
atggtggctcagctgacccagcgtccagtgcacatatgtcatgtggctcggaaggaagag
atcctgttgattaaaactgcaaaggcgcaggggctgccagtgacctgtgaggtcgctcct
caccacctgttcctaaaccgggaagacttggagcgcctgggacctgggaagggagaggtc
cgtcctgagcttgggtcccgagaggatatggaagccctgtgggagaatatggcagtcatc
gactgttttgcctcagaccacgctccccataccttggaagagaagtgtgggcccaagcct
ccacctggcttcccgggcctagagaccatgttgccgctgctgctgacagctgtgagcgag
ggccgcctcagtctggatgacctgctgcagcgattgcaccacaaccctcggcggatcttc
cacctgcctctccaggaggacacctatgtagaggtggatctggagcatgagtggacagtc
cccagccacatgcccttctctaaggcccgctggaccccatttgaaggacagaaggtgaag
ggcacagtgcgccgtgtggtcttgcgaggggaggtcgcctatattgatggacaggtgctg
gtacccccgggctatggacaagatgtacggaagtggccgcagggggttgttccccagccc
cctccttcaactcccgccaccaccgaaatcaccacgacacctgagcgaccacgccgagtc
atcccgggccttcctgatggccgcttccacctgccaccccgcatccaccgggcctctgac
ccaggtctgccagctgaggaacctaaagagaagccacccaggaaggtagtggaaccagag
ctgatgggaacccctgatggtccctgctaccctgcaccaccagtacctagacaggcatca
ccccagaacctagggtcttctggcctgctgcacccccagatgtcgcccctactgcactcc
ctagtgggccagcacatcctgtctgtcaagcagttcactaaggatcagatgtctcatctg
ttcaatgtggcgcacacgctacggatgatggtacagaaggagcggagcctcgacatcctg
aaggggaaggtcatggcctccatgttctacgaggtgagcacccgcaccagtagctccttc
gcagcagccatggcccggctcgggggcgctgttctcagcttctcagaagctacatcctcc
gtccaaaagggcgagtcccttgctgactcggtgcagaccatgagttgctatgctgatgtc
attgtgctccgacaccctcagcctggagccgtggagctggcagccaagcactgtcgcagg
ccagtgatcaatgctggggatggagttggggagcaccccacacaggccctgctggacatc
ttcaccattcgagaagagctggggactgtcaatggcatgacgatcactatggtcggtgac
ctgaagcatggacgcacagtgcactccctggcctgcctgctcacccagtaccgtgtgagc
ctacgctacgtggcacctcccagcctgcgcatgccacccagtgtacgggactttgtggcc
tcccgaggcaccaagcaggaggagtttgagagcatcgaggaggcgctgcccgacacagac
gtgctctacatgactcggatccagaaagaacgatttggctctgtccaggaatatgaagct
tgctttggtcagttcatcctcactcctcacatcatgacccgggccaagaagaagatggtg
gtgatgcacccaatgccccgtgtcaatgagataagtgtggaggtggactcggacccccgg
gcagcctacttccgccaagctgagaacggcatgtacatccgcatggccctgcttgccacc
gtgcttggccgtttctag
DBGET
integrated database retrieval system
