Mycobacterium tuberculosis KZN 4207: TBSG_02865
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Entry
TBSG_02865 CDS
T01690
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase metE
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
mtk
Mycobacterium tuberculosis KZN 4207
Pathway
mtk00270
Cysteine and methionine metabolism
mtk00450
Selenocompound metabolism
mtk01100
Metabolic pathways
mtk01110
Biosynthesis of secondary metabolites
mtk01230
Biosynthesis of amino acids
Module
mtk_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
mtk00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
TBSG_02865
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
TBSG_02865
Enzymes [BR:
mtk01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
TBSG_02865
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Gene cluster
GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
VbhA
SHOCT
Motif
Other DBs
NCBI-ProteinID:
AEB04994
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Position
3147534..3149843
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AA seq
769 aa
AA seq
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MNHPSIEGQHVTQPVRRQPFTATITGSPRIGPRRELKRATEGYWAGRTSRSELEAVAATL
RRDTWSALAAAGLDSVPVNTFSYYDQMLDTAVLLGALPPRVSPVSDGLDRYFAAARGTDQ
IAPLEMTKWFDTNYHYLVPEIGPSTTFTLHPGKVLAELKEALGQGIPARPVIIGPITFLL
LSKAVDGAGAPIERLEELVPVYSELLSLLADGGAQWVQFDEPALVTDLSPDAPALAEAVY
TALCSVSNRPAIYVATYFGDPGAALPALARTPVEAIGVDLVAGADTSVAGVPELAGKTLV
AGVVDGRNVWRTDLEAALGTLATLLGSAATVAVSTSCSTLHVPYSLEPETDLDDALRSWL
AFGAEKVREVVVLARALRDGHDAVADEIASSRAAIASRKRDPRLHNGQIRARIEAIVASG
AHRGNAAQRRASQDARLHLPPLPTTTIGSYPQTSAIRVARAALRAGEIDEAEYVRRMRQE
ITEVIALQERLGLDVLVHGEPERNDMVQYFAEQLAGFFATQNGWVQSYGSRCVRPPILYG
DVSRPRAMTVEWITYAQSLTDKPVKGMLTGPVTILAWSFVRDDQPLADTANQVALAIRDE
TVDLQSAGIAVIQVDEPALRELLPLRRADQAEYLRWAVGAFRLATSGVSDATQIHTHLCY
SEFGEVIGAIADLDADVTSIEAARSHMEVLDDLNAIGFANGVGPGVYDIHSPRVPSAEEM
ADSLRAALRAVPAERLWVNPDCGLKTRNVDEVTASLHNMVAAAREVRAG
NT seq
2310 nt
NT seq
+upstream
nt +downstream
nt
gtgaaccacccgtcgatcgaaggacagcacgtgacccagcctgtacgtcgtcaacccttt
accgcaaccatcaccggctccccgcgcatcggcccgcgccgcgaactcaagcgcgccacc
gaaggctactgggccggacgtaccagccgatccgagctggaggccgtcgccgccacgtta
cgccgcgacacctggtcggccctggccgcggccggtctggactcggtgccggtgaacacc
ttctcctactacgaccaaatgctcgataccgcggtgctgctcggcgcgctgccgccccga
gtgagcccggtttccgacgggctggaccgctatttcgccgcggcgcggggcaccgaccag
atcgcgccgctggagatgacgaagtggttcgacaccaactaccactacctggtacccgag
atcgggccgtcgaccacgttcacgctgcaccccggcaaggtgctcgccgaactcaaagag
gcgttagggcaaggcattcccgcacgtccggtgatcatcgggccgatcaccttcctgctg
ctgagcaaggccgtcgacggcgcgggggcgccgatcgaacgcctcgaagagttggttccg
gtctattcggagctgctgtcgctgcttgccgacggcggcgcccagtgggtgcagttcgac
gagccggcgctggtgaccgacctctcccccgacgcgcccgccctggctgaagcggtgtac
accgcgctgtgctcggtgagcaaccggcctgcgatctatgtcgccacctacttcggggac
ccgggcgcggccctaccggcgctggctcgcaccccggtcgaagccatcggcgtcgacctg
gtggccggtgccgacacctcggtggccggggtacccgagctggccggcaagacgctggtg
gccggggtcgtcgacgggcgcaacgtctggcgcaccgacctggaggcggcgttgggcacg
ttggcgaccctgctgggttcggcggctaccgtggccgtctcgacgtcgtgctcgacactg
cacgtgccgtactcgctggaaccggaaaccgacctggatgacgcgttgcggagctggctg
gcgttcggtgccgaaaaggtgcgcgaagtcgtcgttctcgcgcgtgccctgcgcgacgga
cacgacgcggtcgccgacgagatcgcgtcgtcccgcgccgccatcgcgtcccgcaagcgc
gacccgcggttacacaatgggcaaatccgggcgcgcatcgaggcgatcgtcgcgtccgga
gcccaccgcggcaatgccgcccagcgccgcgccagccaagacgcgcgactgcacctgccg
ccgctgccgaccacgacgatcggctcctacccgcagacctcggcgatccgcgttgcgcgt
gcggcgctgcgggccggtgagatcgacgaggccgagtacgtgcgccggatgcggcaagag
atcaccgaggtgatcgcgctacaggagcggctcgggctcgacgtgctggtgcacggcgaa
ccggagcgcaacgacatggtgcagtacttcgccgagcaattggcgggtttcttcgctacc
cagaacggctgggtgcagtcctacggcagccgctgtgtgcgtccgccgatcctgtacggc
gacgtgtcccggccgcgggcgatgacggtcgagtggatcacctacgcgcagtcgctgacc
gacaaaccggtgaagggcatgttgaccgggccggtgacgattctggcgtggtcgttcgtg
cgtgacgaccagccgttggccgataccgccaaccaggtggcgctggcgattcgcgacgag
accgtggatttgcagtccgccggcatcgcggtcatccaggtcgacgagcctgcgctgcgt
gaactgctgccgctgcgtcgcgccgaccaggccgagtacttgcgttgggcggtaggggct
ttccggttggccacctccggcgtctcggacgccacccagatccacacgcatctgtgctac
tcggagttcggcgaggtgatcggcgcgatcgccgatctggacgcggacgtcacgtccatc
gaggcggcccggtcacacatggaggtgctcgacgacctgaacgcgatcggcttcgccaac
ggtgtgggcccgggcgtctatgacattcactcgccacgggtgccctccgctgaggagatg
gccgactcgttgcgggccgcgttgcgcgcggtgccggccgagcggctgtgggtcaacccc
gactgcggactgaagacccgcaatgtcgacgaggtgaccgcgtcgctgcacaacatggtc
gccgccgcccgggaggtgcgcgcgggctag
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