Mycobacterium tuberculosis 7199-99: MT7199_3769
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Entry
MT7199_3769 CDS
T02617
Symbol
gshA
Name
(GenBank) GLUTAMATE-CYSTEINE LIGASE GSHA (GAMMA-GLUTAMYLCYSTEINE SYNTHETASE) (GAMMA-ECS) (GCS) (GAMMA-GLUTAMYL-L-CYSTEINE SYNTHETASE)
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
mtub
Mycobacterium tuberculosis 7199-99
Pathway
mtub00270
Cysteine and methionine metabolism
mtub00480
Glutathione metabolism
mtub01100
Metabolic pathways
mtub01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mtub00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
MT7199_3769 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
MT7199_3769 (gshA)
Enzymes [BR:
mtub01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
MT7199_3769 (gshA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
CCG13617
LinkDB
All DBs
Position
complement(4156539..4157837)
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AA seq
432 aa
AA seq
DB search
MTLAAMTAAASQLDNAAPDDVEITDSSAAAEYIADGCLVDGPLGRVGLEMEAHCFDPADP
FRRPSWEEITEVLEWLSPLPGGSVVSVEPGGAVELSGPPADGVLAAIGAMTRDQAVLRSA
LANAGLGLVFLGADPLRSPVRVNPGARYRAMEQFFAASHSGVPGAAMMTSTAAIQVNLDA
GPQEGWAERVRLAHALGPTMIAIAANSPMLGGRFSGWQSTRQRVWGQMDSARCGPILGAS
GDHPGIDWAKYALKAPVMMVRSPDTQDTRAVTDYVPFTDWVDGRVLLDGRRATVADLVYH
LTTLFPPVRPRQWLEIRYLDSVPDEVWPAVVFTLVTLLDDPVAADLAVDAVEPVATAWDT
AARIGLADRRLYLAANRCLAIAARRVPTELIGAMQRLVDHVDRGVCPADDFSDRVIAGGI
ASAVTGMMHGAS
NT seq
1299 nt
NT seq
+upstream
nt +downstream
nt
atgacgcttgccgccatgaccgccgcggcctcgcagctggataacgctgccccggacgac
gtcgagatcaccgattcatcggccgccgcggaatacatcgcggacggctgcctcgtcgat
ggtccgttgggacgcgtcggtctggagatggaggcgcactgcttcgacccggccgatccg
tttcgccggcccagctgggaagagatcaccgaggttctcgaatggctcagtccgctgccg
ggcggcagcgtggtcagcgtggagcccggtggtgccgtcgaactgtccggaccgcccgcc
gacggcgtgctggcagccatcggtgccatgacgcgcgatcaggcggtgctacggtcggcg
cttgccaatgccgggctgggtttggtcttcctgggtgcagacccgctgcggtcgccggtg
cgggtcaatccgggcgcacgctatcgggccatggagcagtttttcgccgccagccatagc
ggagtgccgggtgcggcgatgatgacctcgacagccgcgatccaggtcaatctggatgcc
ggaccgcaggaaggatgggctgagcgagtccgcctggcgcacgccttggggccgacgatg
atcgcgattgccgccaactccccgatgctgggcggccggttttccggctggcagtccacc
cggcagcgggtgtggggccagatggactccgcgcgctgcggccccattcttggtgccagt
ggcgaccaccccggcatcgactgggctaagtatgccttgaaggcgccggtgatgatggtg
cgaagcccggacactcaagacacccgtgcggtgacggactacgtgcccttcaccgactgg
gttgacggtcgggtgctgctggacggtcgccgcgctaccgtcgccgacctggtttaccac
ctgacaacgttgttcccgccggtgcgtcctcggcaatggctggaaattcgctacctcgac
agcgtgcccgacgaggtgtggcccgcggtggtgttcaccttggtgacgctgctcgacgac
ccggtggcggcagatttggcggtcgacgcggtcgaaccggtggccacggcctgggacacc
gcggcccggatcggcctggccgaccggcggctctacctggcagccaacagatgcctggcc
atcgccgcgcggcgggtaccgactgaactcatcggcgcgatgcagcggttggtggaccac
gtcgacaggggtgtttgcccggcagacgatttctccgaccgggtgatcgcgggcggcatc
gcgtcagccgtcaccgggatgatgcacggggcgtcgtga
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