Methylosinus trichosporium: CQW49_06725
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Entry
CQW49_06725 CDS
T05155
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mtw
Methylosinus trichosporium
Pathway
mtw00280
Valine, leucine and isoleucine degradation
mtw00640
Propanoate metabolism
mtw00785
Lipoic acid metabolism
mtw01100
Metabolic pathways
mtw01110
Biosynthesis of secondary metabolites
mtw01210
2-Oxocarboxylic acid metabolism
Module
mtw_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mtw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
CQW49_06725 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
CQW49_06725 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CQW49_06725 (pdhA)
Enzymes [BR:
mtw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
CQW49_06725 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
HTH_41
Motif
Other DBs
NCBI-ProteinID:
ATQ67615
UniProt:
A0A2D2CY08
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Position
1410269..1411411
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AA seq
380 aa
AA seq
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MKSANRRLKSRMMLEAENAMVADVSIPIDPLRFLAPDGALCGAPPAEAIAPELALRLYHA
MARTRAYDSKAVALQRTGKLGTFASALGQEAIGVGVGAAMREEDVLAPSYRDHGAQLLRG
MSMTENLVYWGGDERGSDYAVPRRDFPICVPVGTQIAHAVGAAYAFKLRGEASVAVAIIG
DGGTSTGDFYSALNMAGVFDVPLVVVVNNNQWAISTPCSLETAAPTIAHKAIAAGVAGLR
VDGNDALAMHHVANRAIETARSGGGATLIEALSYRLGDHTTADDATRYRDPDVVRRAATQ
EPIARLRNYLTKRGLWNEEDEARLGRENAEEVERAVEAYLATPPQSFAAMFDHLFAQLPP
SMRDQYEEARRFASDGARHG
NT seq
1143 nt
NT seq
+upstream
nt +downstream
nt
atgaaaagcgcgaaccggcgccttaagtcgcgcatgatgctcgaggccgagaacgccatg
gttgcagacgtctcgattccgatcgacccgcttcgtttcctcgcgcccgacggcgcgctc
tgcggcgcgccccctgcggaggcgatcgcgcccgagctcgcgctgcggctctatcacgcc
atggcgcgcacgcgcgcctatgacagcaaggccgtcgctctgcaacgcacgggcaagctc
ggcactttcgcctcggcgctcggccaggaggcgatcggcgtcggcgtcggcgcggcgatg
cgcgaggaggatgtgctcgcgccctcctatcgcgaccatggcgcgcagcttctgcgcggc
atgagcatgacggaaaatctcgtctattggggaggcgacgagcgcggcagcgattacgcc
gttccgcgccgggattttccgatctgcgttcccgtcggcacacagatcgcgcatgcggtc
ggcgccgcctacgccttcaagctgcgcggcgaagcgagcgtcgcggtcgccatcatcggc
gacggcggcacctcgaccggcgatttctattcggccttgaacatggccggcgtcttcgat
gttccgctcgtcgtcgtcgtgaacaataatcaatgggcgatatcgacgccctgcagcctg
gagaccgctgcgccgacgatcgcgcacaaggcgatcgccgccggagtcgctggattgcgc
gtcgacggcaatgacgcgctcgccatgcatcatgtcgcaaatcgcgcgatcgagaccgcg
cgcagcggcggcggggcgacgctgatcgaagcgctgagctatcggctcggcgaccatacg
acggccgatgacgcgacgcgctatcgcgatcccgatgtcgtgcggcgcgccgcgacgcag
gagccgatcgcgcggctgcgcaattatctgaccaagcgtggcctctggaacgaagaggat
gaagccaggctcgggcgcgaaaacgccgaggaggtggagcgcgcggtcgaagcctatctg
gcgacgccgccgcagagctttgcggccatgttcgatcatctgttcgcgcagcttccgccg
tcgatgcgcgatcaatatgaggaagcgcggcgcttcgcctccgacggagcgcgtcatggc
tga
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