KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103729733Help
Entry
103729733         CDS       T03372                                 

Gene name
Hkdc1
Definition
(RefSeq) hexokinase domain containing 1
  KO
K00844  
hexokinase [EC:2.7.1.1]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
Glycolysis / Gluconeogenesis
Fructose and mannose metabolism
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Neomycin, kanamycin and gentamicin biosynthesis
Metabolic pathways
Carbon metabolism
HIF-1 signaling pathway
Insulin signaling pathway
Type II diabetes mellitus
Carbohydrate digestion and absorption
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:ngi00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    103729733 (Hkdc1)
   00051 Fructose and mannose metabolism
    103729733 (Hkdc1)
   00052 Galactose metabolism
    103729733 (Hkdc1)
   00500 Starch and sucrose metabolism
    103729733 (Hkdc1)
   00520 Amino sugar and nucleotide sugar metabolism
    103729733 (Hkdc1)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    103729733 (Hkdc1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    103729733 (Hkdc1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    103729733 (Hkdc1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    103729733 (Hkdc1)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    103729733 (Hkdc1)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    103729733 (Hkdc1)
Enzymes [BR:ngi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     103729733 (Hkdc1)
Membrane trafficking [BR:ngi04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    103729733 (Hkdc1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
LinkDB All DBs
Position
Un
AA seq 911 aa AA seqDB search
MFAVHLMAFYFTKLKEDQIKKVDRFLYHMRLSDETLLDIMARFQAEMEKGLGKDTNPTAS
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVSEEGKRQVQMESQFYPTPNEIIR
GNGMELFDYVADCLADFMKTKELTHKKLPLGFTFSFPCRQTKLEEGVLLSWTKKFKARGV
QDTDVVSRLTNAMKRHKDLDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSINPGKQLFEKMISGL
YMGELVRLILLKMAKAGLLFGGAKSSALLMKGKIETQHVAAMERYKEGLANTREILVDLG
LDPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLQQNKKQARLRTTVGMDGTLYKIH
PQYPKRLHKVVRKLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFQLT
QEQLLSVRDRMRTELEYGLKKKTHALATVKMLPTYVYGMPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLEYMGLKGAQLPLGFT
FSFPCRQMSIDKGTLVGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVALVNDTVGT
MMTCGYEDPKCEIGLIAGTGSNVCYMEEMRNIELVEGDEGKMCINTEWGGFGDNGCIDDI
CTQYDKEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGMAAI
VEKKREDQGLEHLKITVGVDGTLYKLHPHFSRVLQETVEDLAPQCDVTFMLSEDGSGKGA
ALITAVAKRLQ
NT seq 2736 nt NT seq  +upstreamnt  +downstreamnt
atgttcgcggtacacttgatggcattttacttcaccaagctaaaggaggatcagatcaag
aaggtggacaggttcctgtatcacatgcggctctcagatgagaccctcttggacatcatg
gcccggttccaagctgagatggagaaaggtctagggaaggacacgaaccccacggcctcg
gtgaagatgctgcccaccttcgtcagggccattccagatggttcagaaaacggggagttc
ctttccctggatctgggaggttctaagtttcgagtattgaaggtgcaagtctctgaagag
gggaagcgacaggtccaaatggagagtcagttctacccaacgcccaatgagatcatccgg
gggaatggcatggagctctttgactatgtggctgactgcctggcagacttcatgaagacc
aaagagctgacacacaagaaactgccccttggctttaccttttcttttccctgcagacag
accaagttggaagagggcgtcctgctttcatggaccaagaagttcaaggcccggggggtt
caggatacagatgtggtgagccgcctgaccaacgccatgaagaggcacaaggacctggac
gtggatatcctggctttggtcaatgacaccgtggggaccatgatgacatgtgcctatgat
gatccctactgtgaagtcggcgtcatcatcggaacaggcaccaatgcatgctacatggag
gacatgagcaacatcgacctagtggaaggtgacgaggggaggatgtgcatcaacacagag
tggggggcctttggggacgacggggctttggaggacatccgcacagagtttgacagggag
ctggaccttggctcgatcaaccctgggaagcaactgttcgagaagatgatcagtggcctg
tacatgggggaactggtcaggctcatcttgctgaagatggccaaggctggcctcctgttt
gggggtgcaaaatcctccgctctccttatgaagggcaagattgaaacacagcacgtggct
gccatggagaggtataaagaaggcctggccaacacgagggagatcttagtggatctgggc
ctggacccctcagaggctgactgcattgcagtccagcacgtctgcaccatcgtctctttc
cgctctgccaatctttgtgctgctgctctggcagccatcctgacccgcctccagcaaaac
aagaagcaggcccggctccgtaccacagtgggcatggatggaactctctacaagatacat
cctcagtaccccaaacgcctgcacaaggtggtgaggaaactggtcccaaactgtgatgtc
cgcttcctcctatcagagagtggcagcaccaagggggccgctatggtgactgcagtggcc
tcccgagtgcaggcccagcgtaagcagattgacaaggtgctagctctgttccagctgact
caagagcaacttctgagtgttcgggacaggatgcggactgaacttgagtatgggctgaaa
aaaaaaactcatgccctggctacagtcaagatgttgcccacctatgtctacgggatgcct
gatggcacagagaaaggaaagtttctggctctggatttgggaggaactaacttccgggtc
cttctggtgaagatccgaagtggacggaggtcagtgcgaatgtacaacaagatctttgcc
atccctctggagatcatgcagggtactggtgaggagctgttcgatcatattgtgcagtgc
attgctgacttcctggagtacatgggcctcaagggagcccagctacctctgggcttcacg
ttctcctttccctgtagacagatgagcatcgacaagggaacactcgtagggtggaccaaa
ggcttcaaggctactgactgtgagggggaggacgtggtggacatgctcagagaagctatc
aagaggagaaatgagtttgacctggacatagttgcattggtgaatgacacggtggggacc
atgatgacctgtggctatgaagatcctaagtgtgaaattggcttgattgcagggaccgga
agcaatgtatgctacatggaggagatgaggaacatcgagctggtggaaggggatgaaggg
aagatgtgcatcaacacagagtggggtggatttggagataatggctgcatagatgatatt
tgcactcagtatgacaaggaggtggatgagggatccttgaatcctggcaagcagagatac
gagaaaatgaccagcgggatgtacctgggtgagattgtgcggcagatcctgatagacctg
accaagcaggggctcctcttccgaggacagatttcagagcgactccggaccaggggcatc
tttgaaaccaaattcctgtcccagattgaaagtgatcggctggccctcctgcaggtcaga
aggatcctgcagcagctgggcctggacagtacatgtgaagacagcattgtggtgaaggag
gtgtgtggggctgtgtcccggcgggcggcccagctctgtggtgcaggcatggctgccatt
gtggaaaagaagagagaggaccaggggctggagcacctgaagatcaccgtgggtgtggat
ggcacgctgtacaagctgcaccctcacttctctcgagttctgcaggagacagtggaagat
ctggcccctcagtgtgacgtgacattcatgttgtcagaggacggcagtgggaagggagcg
gctttgatcactgcagtagccaagaggttacagtag

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