Ornithorhynchus anatinus (platypus): 100078764
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Entry
100078764 CDS
T01045
Symbol
CFTR
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa02010
ABC transporters
oaa04024
cAMP signaling pathway
oaa04152
AMPK signaling pathway
oaa04530
Tight junction
oaa04971
Gastric acid secretion
oaa04972
Pancreatic secretion
oaa04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
100078764 (CFTR)
09132 Signal transduction
04024 cAMP signaling pathway
100078764 (CFTR)
04152 AMPK signaling pathway
100078764 (CFTR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
100078764 (CFTR)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
100078764 (CFTR)
04972 Pancreatic secretion
100078764 (CFTR)
04976 Bile secretion
100078764 (CFTR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
oaa02000
]
100078764 (CFTR)
Enzymes [BR:
oaa01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
100078764 (CFTR)
Transporters [BR:
oaa02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
100078764 (CFTR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CFTR_R
ABC_membrane
ABC_tran
SMC_N
AAA_21
AAA_29
T2SSE
AAA_16
RsgA_GTPase
DUF87
nSTAND3
MeaB
NTPase_1
Zeta_toxin
Motif
Other DBs
NCBI-GeneID:
100078764
NCBI-ProteinID:
NP_001229663
Ensembl:
ENSOANG00000008767
UniProt:
Q07DZ6
LinkDB
All DBs
Position
10:39900364..40089312
Genome browser
AA seq
1484 aa
AA seq
DB search
MQRSPLERANLFSKLFFSWTKPILKKGYRQHLELSDIYQIPTADSADNLSEKLEREWDRE
LASKKNPKLINALRRCFFWRFMFYGLLLYLGEVTKAVQPLLLGRIIASYDPDNAHERSIA
YYLGIGLCLLFIVRTLLLHPAVFGLHHIGMQMRIALFSLIYKKTLKLSSRVLDKISTGQL
VSLLSNNLNKFDEGLALAHFVWIAPLQVMLLMGLLWDLLQASAFCGLAVLVVLVLFQAWL
GHRMMKYRDRRAGKINERLVITAEIIENIQSVKAYCWEEAMENMIESLRETELKLTRKAA
YMRYFNSSAFFFSGFFVVFLSVLPSMLTKGIVLRKIFTTISFCIVLRMAVTRQFPWAVQM
WYDSIGAIYKIQDFLQKEEYKTLEYNLTTTDVVMENVTAFWDEGFGELLVKAKQNDSSRK
VSSDDKNLIFSNISLLGPPVLKDISFKIEKGQLLAVAGSTGAGKTSLLMMIMGELEPLEG
KIKHSGRISFSPQFSWIMPGTIKENIVFGVSFDEYRYRSVIKACQLEEEISKFAEKDNTV
LGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTR
ILVTSKMEHLKKADKILILHEGSCYFYGAFSELQNLRPDFSSKLMGYDSFDQFSAERRNS
ILTETLRRFSLDGDAAGSWNETKKQSFKQTGEFGERRKNSILNPLNSIRKFSLVQKAPLQ
MNCIDETLDEPPERKLSLVPDSEPGEAILPRSNMLNPGPVLRARRRQSVLNLMTRPSIHQ
GSSLYKKGSASARKMSVAPQSNMSEMDIYSRRLSKDSGLEISEEINEEDLKECFIDDIES
TTSVTTWNTYLRYMTIHKKLIFVLMMCLVIFLIEVAASLVGLCLFKDGASRMNSTSNLNH
TSTLDWFAVIVTNTSTYYMFYIYVGVADTLLALGFLRGLPLVHSLISVSKILHQKMLHSV
LQAPMSTFNTLKTGSILNRFSKDMAILDDLLPLTIFDFIQLLLIVIGAVTVVSALQPYIF
LASVPVVIAFVLLRAYFLRTSQQLKQLESEARSPIFTHLITSLKGLWTLRAFGRQTYFEA
LFHKALNLHTANWFLYLSTLRWFQMRIEMVFVIFFILVTFISILTTGDGEGKVGIVLTLA
MNIMGTLQWAVNASIDVDSLMRSVSRVFKFIDMPTEEHRPTHPAKNKDISGVLIIENQHV
KREKNWPSGGQMTVQDLTAKYLDGGPAILDNISFSISSGQRVGLLGRTGSGKSTLLFAFL
RLLNTEGDIRIDGISWDAVPVQQWRKAFGVIPQKVFIFSGSFRKNLDPYGQWTDQELWKV
AEEVGLKSVIEQFPGQLDFVLIDGGYVLSHGHRQLMCLARSVLSKAKILLLDEPSAHLDP
ITYQVIRKTLKQAFTNCTVILSEHRIEAMLECQRFLVIEENKVRQYESIQKLLNEKSVFK
QAISHSDKMKLFPIHRRNSSKRLSRPKITALQEETEEEVQDTRL
NT seq
4455 nt
NT seq
+upstream
nt +downstream
nt
atgcagagatcaccgctggagcgagccaacctcttctccaaacttttcttcagctggacg
aaaccgattttgaagaaaggatatagacaacatctggaattgtccgacatatatcaaatt
cccaccgctgattcagctgacaacctatctgaaaaactagaaagggaatgggacagagag
ctggcttccaagaagaaccccaaactcattaatgcccttcgacgatgcttcttctggaga
ttcatgttctatggactcttgctgtatttaggggaggtgaccaaggcagtgcagcctctc
ctcctggggcgaatcattgcctcctatgacccagacaacgctcacgaacgctctatcgcg
tactacctgggcatcggcctgtgtcttctctttattgtgcgcaccctgttgctgcaccct
gccgtttttggcctccatcacatcggaatgcagatgaggatcgccctgttcagtctgatt
tacaaaaagactttaaaattgtcaagccgagtcctggataaaataagcaccggacagctc
gttagccttctttcaaacaacttgaacaaatttgatgaaggtctggcgctggcccatttt
gtgtggatcgcgcctctccaggtgatgctgctgatggggctgctgtgggatctgttgcag
gcctccgccttctgcggcttggcagtcctcgtcgtccttgtcctcttccaagcctggctg
gggcacaggatgatgaagtacagagacagaagagccggaaagataaatgagagacttgtg
atcaccgcagaaattattgagaatatccaatccgttaaagcctactgttgggaggaagca
atggaaaacatgattgaaagcctcagagaaacggaactgaagctgacccgaaaggctgct
tatatgaggtacttcaatagctcagccttcttcttctcggggttcttcgtggtgttcctg
tcggtgctaccctccatgctgaccaagggaattgtcctccgcaagatattcaccaccatc
tcgttctgcattgtactgcggatggcggtcacccggcagttcccctgggccgtgcagatg
tggtacgactccatcggagcgatttacaagatacaggatttccttcaaaaagaagagtac
aagacattggaatacaacttaacaactacagatgttgtgatggaaaacgtaacagctttc
tgggacgagggattcggggaattgctcgtcaaagcaaagcaaaatgacagtagccgaaaa
gtctccagtgatgacaaaaacctcatctttagtaacatctcgctcctcggtccccctgtc
ctcaaagacatcagtttcaagatagaaaaaggacagttgttggctgtagctggatctact
ggggcaggcaagacctcactgctgatgatgatcatgggtgagctggagcctttggaaggc
aaaatcaagcacagcggaaggatctccttctctccccaattctcgtggatcatgccagga
accatcaaggagaacatcgtcttcggggtttctttcgatgagtaccgatacaggagtgtc
atcaaggcctgccaattggaggaggaaatctccaagtttgcagaaaaagataatacagtc
ctgggggaaggtggcatcaccttgagtggaggtcagcgggccagaatttcattagccaga
gcagtgtacaaagatgctgacttatatctcctagactctccttttggctacttggatgtg
cttacggaaaaggaaatatttgaaagctgtgtctgcaagcttatggccaataaaacgagg
atcctcgtcacttccaaaatggaacacttgaagaaagccgacaaaatcttaattctgcac
gaaggcagttgctatttctacggcgcgttttcagaacttcagaacctgcggccagacttc
agctccaagctcatgggctacgactccttcgaccagttcagcgccgaaaggagaaactcc
atcctgacggaaaccctgcggcgtttctccctggacggcgatgccgccggctcctggaat
gaaactaagaagcagtcgttcaagcagacgggagagtttggcgaaagaagaaagaactcc
atcctcaacccgctcaactccatccggaagttctccctggtccagaaggctccgctccag
atgaactgcatcgacgagaccctggacgagccgccggagcggaagctttccctggtaccc
gacagcgagccaggagaggccatcctcccccgcagcaacatgctaaaccctgggccggtg
ctccgagcccggaggaggcagtcggtcctgaatctgatgacccggccttccattcaccaa
ggctcgagcctttacaagaagggcagcgcctcggcccgcaagatgtccgtggcccctcag
tccaatatgtcggagatggatatctattcccggcgcctctcaaaagacagcggattggaa
atcagcgaggagattaacgaggaagatttaaaggagtgctttattgatgacatagagagc
acgacttctgtgaccacatggaatacatatctcagatacatgaccattcacaagaagttg
atttttgtgctaatgatgtgcctagtcatctttttgattgaggtggctgcgtctttggtt
gggctgtgtttattcaaagatggggcctcaagaatgaattccaccagtaatctaaaccac
acgagcacactcgattggttcgccgtgatcgtcaccaacacgagcacctattacatgttt
tatatttatgtgggggtagcagacaccttgcttgccctggggttcctccgtggactcccc
ctggtgcacagcctgatatccgtttccaaaattctccaccagaagatgctgcattcggtc
ctgcaggcgcccatgtcgactttcaacactttgaaaacaggtagcattctcaacagattc
tccaaagatatggccattttggatgaccttctgccacttacaatatttgacttcattcag
ctactgctgattgtgattggagccgtgacagtcgtgtcagctttacaaccctacatcttc
ctcgcctctgtgccagtggtaatagcctttgtattgttgagagcatactttctccgcaca
tcccagcaacttaaacaactggaatctgaagcccggagtccaatatttactcatcttatt
acaagcttaaaggggctatggacattgcgtgcatttggacgccaaacgtattttgaagcg
ctgttccacaaggctctgaatttacacaccgccaactggttcctgtatctgtccactctc
cgctggttccaaatgaggatagaaatggtatttgtcatcttcttcattctggtgaccttc
atctccattttaaccacaggtgatggagaagggaaagttggaattgttctaacattagcc
atgaacatcatgggtacattgcagtgggcagtaaacgcgagcattgatgtggacagtttg
atgcggtctgtgagcagagtatttaaattcatcgacatgccaaccgaggagcacaggccc
acccacccagcaaagaacaaagacatctctggagtcctgatcattgagaaccagcatgtg
aagagagagaagaactggccttcaggaggccaaatgaccgtccaggacctcacagccaag
tacctagatggaggtccggccatcttggacaatatctccttttcgataagttccggtcag
agggtgggcctgctgggaagaacgggctcagggaagagcactttattgttcgcctttttg
aggctgctgaacactgaaggagatatccggatcgatggcatatcctgggacgcagtacct
gtgcagcagtggaggaaggcgtttggagtaatacctcagaaagtattcatattttccgga
agttttcgaaagaacctggatccctatgggcagtggacagaccaggaactatggaaagtg
gcagaggaggttgggctgaaatcggtgatcgaacagttcccggggcagctggactttgtc
ctcatcgacggaggctacgtcctgagccacggccacaggcagctcatgtgcctggccagg
tcggttctcagcaaggcgaaaatcctgctcctcgacgaacccagtgcccacctggacccc
ataacataccaggtcattcgcaaaactctaaagcaagcatttaccaactgcacagtcatc
ctctcagaacacaggatagaagcaatgctcgagtgtcaacgctttctggtgatagaggag
aacaaggtccggcagtacgagtctatccagaagctgctgaatgagaagagcgtcttcaag
caggccatcagccactcggacaaaatgaagctgttccccattcaccgccggaactcgagc
aagcgcttgtccaggcccaaaatcacggccctccaggaggagacggaagaggaagtgcag
gacaccagactctag
DBGET
integrated database retrieval system
