KEGG   Odobenus rosmarus divergens (Pacific walrus): 101373969Help
Entry
101373969         CDS       T05148                                 

Gene name
HK1
Definition
(RefSeq) hexokinase-1 isoform X2
  KO
K00844  
hexokinase [EC:2.7.1.1]
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
Glycolysis / Gluconeogenesis
Fructose and mannose metabolism
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Neomycin, kanamycin and gentamicin biosynthesis
Metabolic pathways
Carbon metabolism
HIF-1 signaling pathway
Insulin signaling pathway
Type II diabetes mellitus
Carbohydrate digestion and absorption
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:oro00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    101373969 (HK1)
   00051 Fructose and mannose metabolism
    101373969 (HK1)
   00052 Galactose metabolism
    101373969 (HK1)
   00500 Starch and sucrose metabolism
    101373969 (HK1)
   00520 Amino sugar and nucleotide sugar metabolism
    101373969 (HK1)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    101373969 (HK1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    101373969 (HK1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    101373969 (HK1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    101373969 (HK1)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    101373969 (HK1)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    101373969 (HK1)
Enzymes [BR:oro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     101373969 (HK1)
Membrane trafficking [BR:oro04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    101373969 (HK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
LinkDB All DBs
Position
Unknown
AA seq 917 aa AA seqDB search
MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFKKEMKNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEQNQNVHMESEIYDTPENIVH
GSGSQLFDHVAECLGDFMEKKKIKDKKLPVGFTFSFPCRQSKIDEGILITWTKKFKASGV
EGMDVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKESLLFEGRITPELLTRGKFKTSDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCISVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH
PQFSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFRLT
KDMLLEVKKRMRAEMDMGLRKQTHEKAVVKMLPSFVRSTPDGTEHGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPKMPLGF
TFSFPCKQTSLDAGILITWTKGFKATDCVGHDVATLLREAIKRREEFDLDVVAVVNDTVG
TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMLEGNDGRMCINMEWGAFGDNGCLDD
IRTIYDRLVDEYSLNAGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRG
IFQTKYLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAA
VVDKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMYQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLREETSS
NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt
atgatcgccgcgcagctcctggcctattacttcaccgagctgaaggatgaccaagtcaaa
aagattgacaagtatctctatgccatgcggctctccgatgaaactctgatagatatcatg
actcgtttcaagaaggagatgaagaatggcctctcccgggattttaatccaacagccaca
gtcaagatgttgccaacgtttgtaaggtccatccctgatggttcagaaaagggagatttc
attgccctggatcttggcgggtcttcctttcgaattctgagggtgcaagtgaatcatgag
caaaaccagaacgttcacatggagtccgagatttacgacaccccggagaacatcgtgcac
ggcagtggaagccagctttttgatcacgtggctgagtgcctgggagacttcatggagaaa
aaaaaaatcaaggacaagaaattacctgtgggattcacgttttctttcccttgtcggcag
tccaaaatagacgagggcatcctgatcacctggacaaagaaatttaaagcgagtggagtg
gagggaatggatgtggtgaagctgcttaacaaagccatcaaaaagcgcggggactacgat
gccaacattgtggccgtggtgaacgacacggtggggaccatgatgacctgtggctatgat
gaccagcagtgtgaagtcggcctcatcatcggcactggcaccaatgcctgctacatggag
gaactgaggcacattgacctggtggaaggcgatgaggggaggatgtgcatcaacacagaa
tggggggccttcggggacgacgggtccctggaagacatccgcaccgagttcgaccgagag
atagaccgcggctccctcaaccctgggaagcagctgtttgagaagatggtcagtggcatg
tacttgggggagctggtgcgactgatcctggtcaagatggccaaggagagcctcttattt
gaagggcggattaccccggagctgctcaccagggggaagttcaagaccagcgatgtgtca
gccattgagaagaataaggaaggcctccacaatgccaaagaaatcctgacccgcctggga
gtggagccatccgatgacgactgtatttcagtccagcacgtgtgtaccattgtctcattt
cgctctgccaacctggtggctgcaacgctgggcgccatcttgaaccgccttcgagataac
aagggcacacccaggctgcggaccacggttggtgtcgacgggtctctttacaagacgcac
ccacagttttcccggcgtttccacaagactctgaggcgcttggtgcccgactccgatgtg
cgtttcctcctctcggagagcggcagcggcaaaggggccgccatggtcaccgcggtggcc
taccgcctggcggagcagcaccgacagattgaggagaccctggcccacttccgcctcacc
aaggacatgctgctggaggtgaagaagagaatgcgggctgagatggatatgggcctgagg
aagcagacgcacgagaaggccgtggtcaagatgctgccctcctttgtccggagcactcca
gatgggaccgagcatggtgacttcttggcccttgatcttggaggaacaaatttccgtgtc
ctgctggtgaaaatccgcagtgggaaaaagagaacggtggaaatgcacaacaagatctat
gccattcccattgaaatcatgcagggcaccggggaagagctgtttgaccacatcgtctcc
tgcatctctgacttcctggactacatggggatcaaaggccccaaaatgcctctgggcttc
acgttctcattcccctgcaagcagacgagcctggatgcgggaatcttgatcacctggaca
aagggttttaaggcaactgactgcgtggggcacgatgtagcaacattactaagggaagca
ataaaaaggagagaggaatttgacctggatgtggtggctgtggtcaatgacacggtgggc
accatgatgacctgtgcttacgaggagcctacctgcgaggttggactcatcgtagggacc
ggcagcaatgcctgctacatggaagaaatgaagaatgtcgagatgctggaggggaatgat
gggcgcatgtgcatcaacatggagtggggtgcctttggggacaacgggtgtctagatgat
atcagaacaatctatgacagacttgtagatgaatattctctaaacgctgggaaacaaagg
tttgagaagatgattagcggtatgtacctgggtgagatcgtccgcaacatcttgattgac
ttcaccaagaaggggttcctcttccgagggcagatctctgagacgctgaagacccggggc
atctttcagaccaaatatctttcccagattgagagtgaccggttagcgctgctccaggtc
cgggccatcctccagcagctgggcctgaacagcacctgtgacgacagtatcctggtcaag
accgtgtgcggggtggtgtccaagagggctgcacagctgtgtggtgcgggcatggctgcc
gtggtggataagatccgcgagaacagagggctggaccatctcaatgtgactgtgggcgtg
gatggaacactctacaagcttcatccgcacttctccagaatcatgtaccaaaccgtgaag
gaactgtcccccaaatgtaacgtgtccttcctcctgtccgaagacggtagcggcaagggg
gctgctctcatcacggcagtgggcgtccggctccgggaagagacgagcagctaa

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