KEGG   Odobenus rosmarus divergens (Pacific walrus): 101382558
Entry
101382558         CDS       T05148                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro01522  Endocrine resistance
oro04010  MAPK signaling pathway
oro04015  Rap1 signaling pathway
oro04068  FoxO signaling pathway
oro04071  Sphingolipid signaling pathway
oro04114  Oocyte meiosis
oro04148  Efferocytosis
oro04218  Cellular senescence
oro04261  Adrenergic signaling in cardiomyocytes
oro04370  VEGF signaling pathway
oro04380  Osteoclast differentiation
oro04550  Signaling pathways regulating pluripotency of stem cells
oro04611  Platelet activation
oro04613  Neutrophil extracellular trap formation
oro04620  Toll-like receptor signaling pathway
oro04621  NOD-like receptor signaling pathway
oro04622  RIG-I-like receptor signaling pathway
oro04625  C-type lectin receptor signaling pathway
oro04657  IL-17 signaling pathway
oro04658  Th1 and Th2 cell differentiation
oro04659  Th17 cell differentiation
oro04660  T cell receptor signaling pathway
oro04664  Fc epsilon RI signaling pathway
oro04668  TNF signaling pathway
oro04670  Leukocyte transendothelial migration
oro04714  Thermogenesis
oro04722  Neurotrophin signaling pathway
oro04723  Retrograde endocannabinoid signaling
oro04728  Dopaminergic synapse
oro04750  Inflammatory mediator regulation of TRP channels
oro04912  GnRH signaling pathway
oro04914  Progesterone-mediated oocyte maturation
oro04917  Prolactin signaling pathway
oro04926  Relaxin signaling pathway
oro04932  Non-alcoholic fatty liver disease
oro04933  AGE-RAGE signaling pathway in diabetic complications
oro04935  Growth hormone synthesis, secretion and action
oro04936  Alcoholic liver disease
oro05014  Amyotrophic lateral sclerosis
oro05020  Prion disease
oro05022  Pathways of neurodegeneration - multiple diseases
oro05132  Salmonella infection
oro05133  Pertussis
oro05135  Yersinia infection
oro05140  Leishmaniasis
oro05142  Chagas disease
oro05145  Toxoplasmosis
oro05152  Tuberculosis
oro05161  Hepatitis B
oro05163  Human cytomegalovirus infection
oro05167  Kaposi sarcoma-associated herpesvirus infection
oro05169  Epstein-Barr virus infection
oro05170  Human immunodeficiency virus 1 infection
oro05171  Coronavirus disease - COVID-19
oro05205  Proteoglycans in cancer
oro05208  Chemical carcinogenesis - reactive oxygen species
oro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
oro05415  Diabetic cardiomyopathy
oro05417  Lipid and atherosclerosis
oro05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101382558 (MAPK12)
   04015 Rap1 signaling pathway
    101382558 (MAPK12)
   04370 VEGF signaling pathway
    101382558 (MAPK12)
   04668 TNF signaling pathway
    101382558 (MAPK12)
   04068 FoxO signaling pathway
    101382558 (MAPK12)
   04071 Sphingolipid signaling pathway
    101382558 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101382558 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    101382558 (MAPK12)
   04218 Cellular senescence
    101382558 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101382558 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101382558 (MAPK12)
   04613 Neutrophil extracellular trap formation
    101382558 (MAPK12)
   04620 Toll-like receptor signaling pathway
    101382558 (MAPK12)
   04621 NOD-like receptor signaling pathway
    101382558 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    101382558 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    101382558 (MAPK12)
   04660 T cell receptor signaling pathway
    101382558 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    101382558 (MAPK12)
   04659 Th17 cell differentiation
    101382558 (MAPK12)
   04657 IL-17 signaling pathway
    101382558 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    101382558 (MAPK12)
   04670 Leukocyte transendothelial migration
    101382558 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101382558 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    101382558 (MAPK12)
   04917 Prolactin signaling pathway
    101382558 (MAPK12)
   04926 Relaxin signaling pathway
    101382558 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    101382558 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101382558 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    101382558 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    101382558 (MAPK12)
   04722 Neurotrophin signaling pathway
    101382558 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101382558 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101382558 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    101382558 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101382558 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    101382558 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101382558 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101382558 (MAPK12)
   05161 Hepatitis B
    101382558 (MAPK12)
   05171 Coronavirus disease - COVID-19
    101382558 (MAPK12)
   05163 Human cytomegalovirus infection
    101382558 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101382558 (MAPK12)
   05169 Epstein-Barr virus infection
    101382558 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101382558 (MAPK12)
   05135 Yersinia infection
    101382558 (MAPK12)
   05133 Pertussis
    101382558 (MAPK12)
   05152 Tuberculosis
    101382558 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101382558 (MAPK12)
   05140 Leishmaniasis
    101382558 (MAPK12)
   05142 Chagas disease
    101382558 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101382558 (MAPK12)
   05020 Prion disease
    101382558 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    101382558 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101382558 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    101382558 (MAPK12)
   05415 Diabetic cardiomyopathy
    101382558 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101382558 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    101382558 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101382558 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101382558 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oro01001]
    101382558 (MAPK12)
Enzymes [BR:oro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101382558 (MAPK12)
Protein kinases [BR:oro01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101382558 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Haspin_kinase
Other DBs
NCBI-GeneID: 101382558
NCBI-ProteinID: XP_004409721
UniProt: A0A2U3WLB3
LinkDB
Position
Unknown
AA seq 367 aa
MSSPPPARRGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRIQFLVYQMLKGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSAGCIMAEMITGKTLFKGSDHLDQLKEIMK
VTGTPPAEFVQRLQSADAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAERRV
TAAEALTHPYFESLQDTEDEPKAQKYDESFDDMDRTLDEWKRVTYKEVLSFKPPRQLGTK
VSKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctctccaccacccgcccgcaggggcttttaccgccaggaggtgaccaagacggct
tgggaggtgcgcgccgtgtaccaggacctgcagcccgtgggctccggcgcctacggcgcg
gtgtgctcggccgtggacagccgcactggcgccaaggtggccatcaagaaactgtaccgg
cccttccagtcggagctcttcgccaagcgcgcctaccgcgaactgcgcctcctcaagcac
atgcgccacgagaacgtcatcgggctgctggacgtgttcacccctgatgaaaccctggat
gatttcacagacttttacctggtgatgccgttcatggggactgacctgggcaagctcatg
aagcacgagaagctgagtgaggaccgaatccagttccttgtctaccagatgctgaagggg
ctaaagtacatccatgctgctggcatcatccatagggacctgaagcccggcaatctggca
gtgaatgaggactgtgagctgaagatcctggacttcggcctggcgaggcaggcagacagc
gagatgactgggtatgtggtgactcggtggtaccgggcacctgaggtcatcttgaattgg
atgcgctacacacagacagtggatatctggtcggcgggctgcatcatggcggagatgatt
acagggaagacgctgttcaagggcagtgaccacctggaccagctgaaggagatcatgaag
gtgacagggacgcctcccgctgagtttgtgcagaggctgcagagtgccgatgcgaagaac
tacatgaagggcctccccgagttggagaagaaggatttcgcatccatcctgactaatgca
agtcctctggctgtgaacctcctggagaaaatgcttgtgctagatgcagagcggcgggtg
actgcggccgaggcgctgacccacccctacttcgagtcactgcaggacacggaggatgaa
cccaaggcccagaagtacgacgagtcctttgatgatatggaccgcacgctggatgagtgg
aaacgtgtcacatataaagaagtgctcagcttcaagcctccccggcagctggggaccaag
gtctccaaggagacggccctgtga

DBGET integrated database retrieval system