Rothia mucilaginosa: RMDY18_13540
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Entry
RMDY18_13540 CDS
T01144
Name
(GenBank) UDP-N-acetylmuramyl pentapeptide synthase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rmu
Rothia mucilaginosa
Pathway
rmu00300
Lysine biosynthesis
rmu00550
Peptidoglycan biosynthesis
rmu01100
Metabolic pathways
rmu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rmu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
RMDY18_13540
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
RMDY18_13540
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
RMDY18_13540
Enzymes [BR:
rmu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
RMDY18_13540
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAI65186
UniProt:
D2NU60
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All DBs
Position
complement(1520539..1522158)
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AA seq
539 aa
AA seq
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MIKLSAAQIIEATGGTAIGLEGREEQVYADFATTDSREVQTGTLFVAKPGAVTDGHRFIP
MAFERGATLALVEREVLDEQGMPYPSIQVPDVVLAMGDLARYSIEQMRAQGELTVIGITG
SAGKTTTKDLLAAIFAPEGPTVAPVGSYNSEVGVPLTVFRADESTRYLVIEMGADHVGNI
EYLANIAHPDHGAILKVGTAHAGEFGGVDNIERTKGELAEGVQPTGSLALNADDERVLRM
ASRSVAPITYFGVGEKTDANGQPYERYVAALNLRTTDAGCPEFTLRLPDGSEYEISSQLI
GEHHVHNLLAAATIAYNSGISGEKIARALNKAAAASKWRMARTDRADGVTVINDAYNANP
ESMAAALRTLAQLGRTVDPATGQPHRTWAVLGAMLELGDASVEEHDRIGRLVVRMNISKL
IAVGDETKPIYNAAHLEGSWGNEATWVKTPEEAEQILRAEVRPGDIVLFKSSNGAKLGIL
GDQVAFAEYTFGAEEEQAPTWLSAGDFVETTDLSDHLAAHLDGAANGDRTSTEQTTNEG
NT seq
1620 nt
NT seq
+upstream
nt +downstream
nt
atgattaagctcagcgccgcccagattattgaggcaaccggcggcaccgctatcggcctg
gagggccgtgaggagcaggtgtacgcagacttcgccaccaccgactcccgtgaggtgcag
accggtaccctgttcgtggcgaagcccggtgcggtcactgacggtcacaggttcatcccc
atggcgtttgagcggggcgcgaccctggcgctggtcgagcgcgaagtactcgacgagcag
ggcatgccctacccgagcatccaggtgcccgatgtggtgctggcgatgggtgatttggcg
cgctactccattgagcagatgcgcgctcagggtgagctgaccgttatcggtattaccggt
tccgccggtaagaccaccaccaaggaccttcttgccgccattttcgccccggagggcccg
accgttgcgccggttggttcctataacagtgaggtgggcgtgcccctgaccgttttccgt
gcggatgagtctacccgctacctggtcattgagatgggggccgaccacgtgggcaacatc
gagtacctggcgaatattgcgcaccccgatcacggtgcaatcctgaaggtcggtaccgcg
cacgctggcgagttcggcggcgtggacaatattgagcgcactaagggcgagctggctgag
ggtgttcagccgaccggttccctggcgctgaacgctgacgatgagcgcgtgctacgcatg
gcgtcgcgttcggttgcacccattacgtacttcggcgtgggcgagaagaccgacgcgaac
ggccagccctacgaacgctacgtggcggcgctgaacctgcgcaccaccgacgctggctgc
cccgagttcactctgcgcctgcccgacggtagcgagtacgagatttcctcgcagctgatc
ggtgagcaccacgtgcacaacctgctggctgctgcgacaatcgcctacaacagcggtatt
tcgggtgagaagattgctcgcgcgctcaacaaagcggcggcggcttcgaagtggcgtatg
gcgcgcaccgaccgcgctgacggcgtgaccgtcattaacgacgcctacaacgcgaacccc
gagtcgatggctgcggcactgcgcaccctggcgcagctgggtcgcaccgtcgacccggcg
accggtcagccgcaccgcacctgggctgttctgggtgccatgctggagctcggtgacgcc
tccgtggaggagcacgaccgcatcggtcgcctcgtggtgcgcatgaacatttccaagctg
attgctgtgggcgacgagacgaagcccatctacaatgctgctcatctggaaggctcctgg
ggtaatgaggcgacctgggtgaagaccccggaggaggcagagcagattctgcgcgccgag
gttcgccccggcgacattgtgcttttcaagtcctcgaacggggcgaagctgggcattctg
ggtgaccaggttgctttcgccgagtacactttcggcgctgaggaagagcaggcaccgact
tggctttctgccggtgactttgttgaaaccaccgatttgagcgaccaccttgccgctcac
ctggacggtgccgctaatggcgaccgtacttcgaccgaacagaccacgaacgaagggtag
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