REACTION: R08325
Entry
R08325 Reaction
Definition
Valproic acid + NADPH + H+ + Oxygen <=> 4-Hydroxyvalproic acid + NADP+ + H2O
Equation
C07185
+
C00005
+
C00080
+
C00007
<=>
C16649
+
C00006
+
C00001
Comment
CYP2C9, CYP2A6, CTP2B6
Reaction class
RC00001
C00005_C00006
RC01710
C07185_C16649
Enzyme
1.14.13.-
Pathway
rn00982
Drug metabolism - cytochrome P450
Orthology
K17683
cytochrome P450 family 2 subfamily A polypeptide 6 [EC:1.14.13.-]
K17709
cytochrome P450 family 2 subfamily B polypeptide 6 [EC:1.14.13.-]
K17719
cytochrome P450 family 2 subfamily C polypeptide 9 [EC:
1.14.13.48
1.14.13.49
1.14.13.80
1.14.13.-]
LinkDB
DBGET
integrated database retrieval system
