REACTION: R08391
Entry
R08391 Reaction
Definition
Retinoate + NADPH + H+ + Oxygen <=> all-trans-5,6-Epoxyretinoic acid + NADP+ + H2O
Equation
C00777
+
C00005
+
C00080
+
C00007
<=>
C16680
+
C00006
+
C00001
Comment
CYP2A6, CYP2B6, CYP3A4/5, CYP2S1, CYP26
Reaction class
RC00001
C00005_C00006
RC01624
C00777_C16680
Enzyme
1.14.13.-
1.14.14.1
Pathway
rn00830
Retinol metabolism
Orthology
K07411
cytochrome P450 family 2 subfamily A [EC:
1.14.14.1
]
K07412
cytochrome P450 family 2 subfamily B [EC:
1.14.14.1
]
K07420
cytochrome P450 family 2 subfamily S polypeptide 1 [EC:
1.14.14.1
]
K07424
cytochrome P450 family 3 subfamily A [EC:
1.14.14.1
]
K17683
cytochrome P450 family 2 subfamily A polypeptide 6 [EC:1.14.13.-]
K17689
cytochrome P450 family 3 subfamily A polypeptide 4 [EC:
1.14.13.32
1.14.13.67
1.14.13.97
1.14.13.157
1.14.13.-]
K17690
cytochrome P450 family 3 subfamily A polypeptide 5 [EC:
1.14.14.1
]
K17709
cytochrome P450 family 2 subfamily B polypeptide 6 [EC:1.14.13.-]
LinkDB
DBGET
integrated database retrieval system
