KEGG   REACTION: R08724
Entry
R08724                      Reaction                               
Name
7alpha,27-dihydroxycholesterol:NAD+ 3-oxidoreductase
Definition
7alpha,27-Dihydroxycholesterol + NAD+ <=> 7alpha,26-Dihydroxy-4-cholesten-3-one + NADH + H+
Equation
C06341 + C00003 <=> C17336 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC01111  C06341_C17336
Enzyme
1.1.1.181
Pathway
rn00120  Primary bile acid biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.181
     R08724  7alpha,27-Dihydroxycholesterol + NAD+ <=> 7alpha,26-Dihydroxy-4-cholesten-3-one + NADH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.181
   R04263  7alpha-Hydroxycholesterol <=> 7alpha-Hydroxycholest-4-en-3-one
    R08724  7alpha,27-Dihydroxycholesterol <=> 7alpha,26-Dihydroxy-4-cholesten-3-one
Orthology
K12408  cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase [EC:1.1.1.181]
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